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GlossaryFrontal Fibrosing Alopecia

scarring hair loss at the front hairline, often in postmenopausal women

Frontal Fibrosing Alopecia (FFA) is a type of scarring hair loss that primarily affects postmenopausal women, though it can occur in men and younger women. It is characterized by a progressive recession of the frontal hairline and often includes loss of eyebrows and other body hair. The condition is thought to be an autoimmune disorder, where the body's immune system mistakenly attacks hair follicles, leading to inflammation and permanent hair loss.

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community Concerned About Asymmetrical Frontal Hair Loss and Recent Finasteride Use, Seeking Experiences

in General 155 upvotes 3 months ago

The user is experiencing asymmetrical hair loss at the frontal hairline and is concerned about potential conditions like frontal fibrosing alopecia. They have started using finasteride and pumpkin seed oil to address the issue.

community Fibrosing alopecia in a pattern distribution

in Research/Science 14 upvotes 2 years ago

A user has been experiencing hair loss for 4 years, with treatments like minoxidil, finasteride, and various supplements proving ineffective. They were diagnosed with fibrosing alopecia in a pattern distribution, a condition that may require a combination of anti-inflammatory and hair growth treatments.

community Can topical tretinoin only applied to face (not hairline) exacerbate hair loss?

in Chat 7 upvotes 3 months ago

Topical tretinoin applied to the face may exacerbate hair loss in some individuals, potentially triggering conditions like frontal fibrosing alopecia. Experiences vary, with some users reporting no impact on hair, while others experience significant hair loss.

community Just an encouraging post for atypical alopecia sufferers

in Treatment 4 upvotes 4 years ago

The user experienced eyebrow hair loss and tried various treatments, including Minoxidil, a Capsaicin-based product, Latanoprost, Bimatoprost, Castor Oil, and Travoprost. Despite initial setbacks and a brutal shedding phase, they eventually saw positive results with Travoprost, encouraging others not to give up on treatments.

community scarring alopecia awareness in this community

in Chat 33 upvotes 3 years ago

Lichen Planopilaris (LPP), a form of permanent hair loss, which can be mistaken for seborrheic dermatitis and is characterized by scalp itching, burning, redness, and dandruff. Treatment options discussed include steroidal creams, finasteride, minoxidil, and RU58841.

community Opinions on Scalp fibrosis and DHT?

in Research/Science 9 upvotes 3 years ago

The conversation discusses the theory that scalp fibrosis contributes to male pattern baldness (MPB) by increasing DHT concentration, and mentions treatments like Minoxidil. The user seeks opinions on the theory and the effectiveness of scalp massages.

community My Theory Of Androgenic Alopecia

in Research/Science 20 upvotes 5 months ago

Hair loss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.

community DUPA/Retrograde might not be DHT based...GET A BIOPSY QUICK or permanent Hair Loss!

in Research/Science 41 upvotes 1 year ago

DUPA and retrograde alopecia may not be solely DHT-based, and a biopsy is crucial for accurate diagnosis and treatment. Treatments mentioned include dutasteride, oral minoxidil, pioglitazone, clobetasol, calcipotriol, ketoconazole, and doxycycline, depending on the specific condition.

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 1 year ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Hairloss all over body and head

in Treatment 2 upvotes 3 months ago

A 25-year-old experiencing hair thinning all over the body and head, despite using minoxidil and having low vitamin D levels, is advised to seek a second opinion from a dermatologist specializing in hair loss. The likely diagnosis is diffuse alopecia areata, which may require treatment with a JAK inhibitor.

community can someone help me identify these pls

in Treatment 5 months ago

The user is experiencing diffuse thinning and inflammation despite using 2.5mg dutasteride daily, ciclopirox, and ketoconazole shampoos. They are considering treatments like hydroxychloroquine and JAK inhibitors due to suspected scarring alopecia and have faced challenges in obtaining a scalp biopsy.

community Quote from Pelage (PP-405) Spokesperson...

in Research/Science 122 upvotes 6 months ago

Pelage is developing a topical hair follicle stem cell therapy, PP405, for non-scarring alopecias like androgenetic alopecia, with Phase III trials planned and a potential market launch by 2027. The treatment may not require continuous use after initial regrowth.

community almost 6 months of progress :)

in Progress Pictures 535 upvotes 1 year ago

The user shared their 6-month hair regrowth progress using finasteride, minoxidil, biotin, and iron supplements, along with occasional microneedling and specific shampoos. They reported minimal side effects and no retrograde alopecia, attributing their success to a combination of treatments.

community Totally confused by doctors opinions, would appreciate some clarity

in Treatment 1 upvotes 1 year ago

The user is experiencing hair loss and confusion over conflicting medical advice, with treatments including minoxidil, finasteride, and topical corticosteroids. They are unsure about the necessity of a biopsy and the timing of using minoxidil, while also considering the impact of potential androgenetic alopecia and telogen effluvium.

community Where to Begin with Microneedling?

in Treatment 15 upvotes 2 years ago

User is considering microneedling to enhance hair regrowth after limited response to minoxidil and better results with finasteride and ketoconazole shampoo. Recommendations include using a 1.5mm derma roller once a week, avoiding minoxidil on microneedling days, and disinfecting the roller with isopropyl alcohol.

community What about botox injections on the scalp?

in Research/Science 6 upvotes 3 years ago

Botox injections on the scalp may help with hair loss, as one small study showed improvement in 8 out of 10 subjects. Treatments mentioned include Minoxidil, finasteride, and RU58841.

community Exploring all options - Scalp tension theory

in Research/Science 15 upvotes 1 year ago

The conversation discusses the scalp tension theory as a potential factor in hair loss, alongside DHT, inflammation, and other mechanisms. Treatments mentioned include finasteride, minoxidil, and botox injections, with some users exploring additional methods due to varying effectiveness.

community Male pattern baldness is not cosmetic.

in Chat 222 upvotes 5 months ago

Male pattern baldness is linked to health risks and should be treated medically. Finasteride is effective and should be insurance-covered.

community Scalp tension and thickness of the galea aponeurotica, inflammation and potential treatment pathways

in Research/Science 4 years ago

Scalp tension potentially affecting hair loss, and potential treatments for male pattern baldness such as Minoxidil, Finasteride and RU58841. Evidence from a study was discussed which suggests that the cause of MPB lies within the follicle itself and is not dependent on its surrounding environment.

community M18 - 7 Months on topical fin + min Not working for me

in Finasteride/Dutasteride 92 upvotes 1 year ago

Topical finasteride and minoxidil are not effective for the user, who is considering switching to oral treatments like finasteride or dutasteride. Many suggest oral medications are more effective, and some recommend additional treatments like microneedling and other topical solutions.

community How essential is scalp biopsy when dealing with hair loss?

in Treatment 6 upvotes 1 year ago

The user experienced hair loss despite using Fin and Min for 12 years and switched to Dutasteride, RU58841, and Keto scalp serum, but shedding and itch persist. They are considering increasing Dutasteride to 2.5mg and questioning the necessity of a scalp biopsy, with mixed opinions on its usefulness.

community We Need A Solution For The Inflammatory Response related To AGA

in Research/Science 16 upvotes 1 year ago

The conversation is about finding a solution for scalp inflammation related to AGA, with the user expressing frustration that Minoxidil and Finasteride do not address inflammation. The user has researched glucocorticoids and topical NSAIDs for reducing inflammation and seeks advice from specialists.

community Finasteride not working isnt it MPB?

in Finasteride/Dutasteride 5 upvotes 2 years ago

A user is concerned that finasteride isn't working for their hair loss, questioning if it's due to male pattern baldness or low iron levels. They are advised to take finasteride daily and get blood work done.

community 1 and a half years on fin - hair is way worse.

in Finasteride/Dutasteride 9 upvotes 3 years ago

The user reported worsening hair loss after 1.5 years on finasteride, questioning if chronic iron deficiency could be a cause. They noted no side effects from finasteride.

community I’ve been on dutesteride and oral minoxidil for two years now and I’ve only lost ground… 25m What should I do?

in Treatment 33 upvotes 2 years ago

A user on dutasteride and oral minoxidil for two years has experienced worsening hair loss and an itchy scalp. Suggestions include increasing medication doses, trying other treatments like RU58841, getting a scalp biopsy, and addressing potential inflammation through diet and topical treatments.

community Using a SERM (Ralox) and oral fin at the same time - anyone with similar experiences?

in Finasteride 10 upvotes 6 years ago

The user experienced gynecomastia from finasteride, used raloxifene to treat it, and is now taking both without new gyno symptoms but also without hair regrowth. They are seeking others' experiences with this combination and its effects on hair.

community Interesting article links major MPB theories to western diet (and life-style)

in Research/Science 58 upvotes 1 year ago

Poor diet and lifestyle contribute to male pattern baldness. Treatments like Minoxidil, dietary changes, and lifestyle adjustments may help slow hair loss.

community Dutasteride Isn't Working? Get a Scalp Biopsy NOW

in Finasteride/Dutasteride 19 upvotes 1 year ago

Dutasteride may not be effective for everyone due to underlying issues, suggesting scalp biopsies for further diagnosis. Users discuss using higher doses of dutasteride, topical treatments, minoxidil, and pyrilutamide for hair loss management.

community I think I’ve finally found the reason for my hair loss

in Chat 98 upvotes 1 year ago

The user experienced hair loss since 2019 and tried finasteride, dutasteride, RU58841, and ketoconazole shampoo without success. A scalp biopsy showed scarring and inflammation from folliculitis, indicating chronic inflammation was affecting treatment effectiveness.

community Why do patients drop back to baseline/pre-treatment soon after quitting Finasteride?

in Research/Science 10 upvotes 5 months ago

Stopping finasteride often leads to rapid hair loss, returning to a genetic baseline, as the drug temporarily halts hair loss and promotes regrowth. The discussion explores the complexity of hair loss, suggesting that factors beyond DHT, such as genetics and scalp conditions, may play a role.