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    Did you mean Gamma-Aminobutyric Acid?
    GlossaryGamma-Aminobutyric Acid

    neurotransmitter that inhibits nerve activity, promoting relaxation

    Gamma-Aminobutyric Acid, commonly known as GABA, is a neurotransmitter in the brain that inhibits nerve transmission, helping to regulate nervous system activity and reduce neuronal excitability. It plays a crucial role in promoting relaxation and reducing stress, and imbalances in GABA levels are associated with conditions like anxiety, epilepsy, and insomnia.

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      community Finasteride does deplete important nuero-active steroids

      in Research/Science  9 upvotes 2 years ago
      Finasteride can reduce neuroactive steroids, causing side effects like depression, anxiety, and sexual dysfunction. Some users experience persistent symptoms after stopping finasteride, while others use alternative treatments like topical solutions.

      community Targeting multiple AGA mechanisms with commonly available substances

       4 upvotes 7 years ago
      The conversation discusses using a multimodal approach to treat androgenic alopecia, including substances like gamma-linolenic acid, DHA, sulforaphane, melatonin, cetirizine, astaxanthin, fisetin, apigenin, curcumin, limonene, genistein, and berberine. Users also mention using ketoconazole, minoxidil, and low-level laser therapy (LLLT) as part of their hair loss treatment regimens.
      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 1 year ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Has anyone here tried taking GLA supplements?

      in Treatment  1 upvotes 1 year ago
      GLA may help with hair loss due to its anti-inflammatory properties and 5ar enzyme inhibition. It's considered potentially more important than biotin, especially for those already using finasteride and dutasteride.

      community Can amino acids help with AGA

      in Chat  4 upvotes 2 years ago
      Amino acids like lysine, methionine, and cysteine may help with androgenetic alopecia when taken in high doses along with a DHT blocker. Users discuss combining these with treatments like Minoxidil, finasteride, and RU58841.

      community Helicobacter's concocted serum v1

       6 upvotes 7 years ago
      A custom-made serum based on double-blind studies for AGA, which includes natural ingredients such as rosemary oil, procyanidin B-2, saw palmetto extract, curcuma aeruginosa, pumpkin seed oil and castor oil. The user has updated their recipe to include apple poly procyanidin B-2 4% concentration and other ingredients before topping it off with Pura d'or serum.

      community Methionine? Glycine?

       6 upvotes 10 years ago
      The conversation discusses the potential benefits and risks of using Methionine and Glycine for hair loss, with concerns about cancer risk if not balanced properly. The user seeks opinions on these amino acids for hair health and overall benefits.

      community Can Whey Protein isolate make your AGA worse?

      in Product  9 upvotes 3 years ago
      Whey protein isolate may worsen androgenetic alopecia (AGA) due to its potential to increase DHT levels, but finasteride use has helped maintain hair. Some users suggest avoiding protein supplements due to possible contaminants and additives that could affect hair health.

      community You will lose hair if your prostaglandins aren't in balance

      in Research/Science  56 upvotes 1 year ago
      Prostaglandin balance affects hair loss, particularly in conditions like Lichen Planopilaris, where an imbalance can lead to hair follicle damage. Treatments mentioned include prostaglandin analogs and Pioglitazone HCL, with a focus on maintaining prostaglandin equilibrium for potential hair regrowth.

      community ASATONA AG and "Asatex"

       4 upvotes 7 years ago
      The conversation discusses Melatonin's potential benefits for AGA and a product called "Asatex" by ASATONA AG. The company was uncooperative when contacted for purchase inquiries.

      community Hair Loss & Lipids: Why you have sebderm, folliculitis, LPP, inflammation, etc...

      in Research/Science  132 upvotes 1 year ago
      Excess sebum rich in cholesterol and triglycerides can lead to hair loss through inflammation, with treatments like Ciclopirox shampoo, Benzoyl Peroxide shampoo, and Clindamycin gel recommended for managing conditions like seborrheic dermatitis and folliculitis. Pioglitazone is suggested for Lichen Planopilaris, while Omega-3s and reducing processed foods may improve sebum quality, though genetic factors play a significant role.

      community Tazarotene better than Tretinoin with minoxidil?

      in Chat  9 upvotes 1 year ago
      Switching from tretinoin to tazarotene with minoxidil led to new hair regrowth after years of maintenance. Tazarotene's selectivity and higher concentration might be more effective for hair growth.

      community The Worst Hair Loss Condition You (MAY) have: LPP

      in Research/Science  50 upvotes 1 year ago
      Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

      community CHECKLIST: Blood and other test before starting treatment

      in Treatment  4 upvotes 1 year ago
      Before starting hair loss treatment, it's suggested to undergo various blood and health tests to minimize side effects. The checklist includes tests for kidney function, liver enzymes, blood sugar, vitamins, hormones, and more.

      community Vitamin E

       18 upvotes 7 years ago
      Vitamin E was discussed as a treatment for hair shedding, with a specific form mentioned. A user shared a link to a study and started taking the Vitamin E variants used.

      community Alpha plus from Anagenica - 25%CB???

      in Product  2 upvotes 2 years ago
      A user ordered Alpha Plus from Anagenica, expecting it to contain specific percentages of Fin, Estradiol, Minoxidil, and CB0301. However, the received product's label showed different percentages, including a surprising 25% CB, leading the user to question its safety and accuracy.

      community GT20029 China Phase II Trial For AGA Reached Primary Endpoint

      in Research/Science  133 upvotes 2 years ago
      The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.

      community Baby hair growth from non existent to existing.

      in Progress Pictures  173 upvotes 8 months ago
      A user shared progress pictures showing hair regrowth after using minoxidil and finasteride for several months. Despite skepticism, the user reports noticeable improvement and aims to motivate others with hair loss.
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