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      community Just started DualGen-15 Plus ( w/Finasteride )

      in Finasteride  11 upvotes 7 years ago
      A user discusses their hair loss journey, starting with 5% minoxidil and nizoral, and now using DualGen-15 Plus with 15% minoxidil and 0.1% finasteride. They also use biotin, pumpkin seed oil, Pura D'or Professional shampoo, and derma rolling, noting some shedding and side effects.
      Compunded Oral Minoxidil, As Efficient As Tablet Variants?

      community Compunded Oral Minoxidil, As Efficient As Tablet Variants?

      in Minoxidil  146 upvotes 5 months ago
      The user discusses using compounded oral minoxidil due to the ineffectiveness and inconvenience of topical minoxidil for diffuse thinning. They question the efficacy of compounded minoxidil compared to original tablet forms and express concerns about the importance of excipients and binders.

      community Betamethasone dipropionate 0.05 (sernivo spray)

      in General  76 upvotes 1 year ago
      A user was prescribed betamethasone dipropionate spray for a receding hairline, which caused skin peeling and depigmentation. They stopped using it and are considering alternatives like BPC-157/TB-500 for healing.

      community Once daily topical Min, weekly 1.5 mm dermarolling

      in Progress Pictures  35 upvotes 2 years ago
      The user has been using 5% minoxidil once daily and microneedling with a 1.5 mm dermaroller weekly for three months, considering increasing minoxidil usage but avoiding finasteride due to libido concerns. Another person suggests considering other treatments like RU58841, alfatradiol, topical finasteride, clascoterone, or saw palmetto since not using a DHT blocker could be less effective.

      community 1 year on Dut + Oral Minoxidil

      in Progress Pictures  109 upvotes 3 weeks ago
      A 28-year-old male experienced significant hair regrowth using dutasteride 0.5 mg and 2.5 mg oral minoxidil after previous treatments with minoxidil and finasteride became less effective. He reported no major side effects, except for unwanted hair growth in certain areas.

      community 28M 0.5MG DUT 5MG MIN - PROGRESS PIC & THANKS

      in Progress Pictures  76 upvotes 1 week ago
      A 28-year-old male shares progress on hair loss treatment using 0.5mg dutasteride and 5mg minoxidil, experiencing initial shedding but encouraged by community support. He also uses ketoconazole occasionally based on scalp oiliness.

      community from fin to dut; from oral to topical minoxidil

      in Is this regrowth?  118 upvotes 1 year ago
      The user switched from finasteride to dutasteride and from oral to topical minoxidil, noticing better hair regrowth with the new regimen. They experienced no side effects from dutasteride and found topical minoxidil more effective than oral.

      community Redensyl Megathread !!!!

       46 upvotes 6 years ago
      Redensyl, which is a topical alternative to Minoxidil for hair loss. It may have advantages such as not making the hair greasy and lasting longer after discontinuing use than minoxidil. There are some positive reports from users, but also some negative ones, so it's unclear how effective this treatment will be in comparison to Minoxidil and other treatments like Finasteride or RU58841.

      community Minoxidil its giving me huge water retention

      in Minoxidil  128 upvotes 11 months ago
      Minoxidil caused water retention and gastrointestinal issues for the user, which improved after stopping the medication. The user is now using finasteride and topical minoxidil, experiencing excessive urination and concerns about systemic absorption.

      community topical fluridil/eucapil + dut to block all DHT+T from scalp?

      in Treatment  8 upvotes 3 years ago
      User experienced slow gains with topical fin+min, switched to topical dut+min, and considered adding Eucapil. Another user suggested DUT may be less effective topically due to high molar mass and mentioned Fluridil as a weak anti-androgen that could help.

      community Possibilities without Fin/Dut ?

      in Treatment  4 upvotes 1 month ago
      The user experiences severe side effects from finasteride and dutasteride, including low libido and anxiety, and is currently using oral minoxidil despite shortness of breath. They are seeking alternative treatments for hair loss, having tried pyrilutamide, fluridil, and RU58841 with no success, and are considering future treatments or a hair transplant.

      community I ended up in the ER due to oral Minoxodil.

      in Minoxidil  6 upvotes 3 years ago
      A user experienced severe side effects, including heart issues, after taking oral minoxidil without consulting a doctor. They are now considering alternatives like dutasteride, PRP, or laser treatments for hair loss.

      community Whats the deal with TDM-105795?

      in Research/Science  4 upvotes 1 month ago
      TDM-105795 is a potential hair growth stimulant that works differently from minoxidil and could be used alongside it for enhanced growth. It completed phase 2 trials in 2024, with a medium to high chance of release in 2026, but lacks recent updates or phase 3 trial information.

      community What are the alternatives to spironolactone for AGA?

      in Female  8 upvotes 1 year ago
      The user experienced side effects from spironolactone and is seeking alternatives for androgenetic alopecia (AGA), considering saw palmetto but unsure of its effectiveness. They are also exploring the possibility of using topical spironolactone, despite availability challenges.

      community Dut only? Had to drop oral minoxidil

      in Treatment  2 upvotes 9 months ago
      The user stopped oral minoxidil due to side effects and is now using dutasteride mesotherapy and plans to start oral dutasteride. They are concerned about potential hair shedding and wonder if dutasteride alone will be effective.
      Is Dut enough or should I add Min?

      community Is Dut enough or should I add Min?

      in Journals / Progress Pictures  92 upvotes 1 year ago
      The user is considering adding minoxidil to their current dutasteride treatment to recover lost hair, particularly in the temple areas. Other users suggest that minoxidil is necessary for better results, with one user sharing their positive experience using a combination of minoxidil, dutasteride, and other treatments.

      community Is there any new drug that looks promising ?

      in Research/Science  25 upvotes 2 years ago
      The conversation discusses GT20029, a drug in Phase II trials that targets androgen receptors with minimal systemic effects, and TDM-105795, a growth stimulant with a different mechanism than minoxidil that may revive papilla stem cells. Both are potential new treatments for hair loss.

      community Treatment with dutasteride, without minoxidil

      in Is this regrowth?  48 upvotes 5 months ago
      The conversation discusses the use of dutasteride for hair regrowth, with the user planning to add topical minoxidil. The user reports improved hair strand quality and beard growth with dutasteride, while noting some side effects compared to finasteride.

      community Diffuse thinning is so brutal.

      in Styling  71 upvotes 2 years ago
      A 25-year-old with AGA experienced hair thinning and dandruff, stabilized with topical finasteride and minoxidil but saw minimal regrowth. They seek advice on styling and consider oral minoxidil and microneedling for denser hair.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community Minoxidil alternate approaches

      in Treatment  2 upvotes 5 months ago
      The conversation discusses hair loss treatments, including the use of 2.5mg Dutasteride, 1mg Finasteride, and Minoxidil 5%, with concerns about side effects like water retention and facial changes. The user is considering alternative Minoxidil applications, such as microneedling and sublingual Minoxidil, to minimize side effects.

      community Creating an all-in one topical. Dumb idea?

      in Treatment 3 years ago
      The user is considering combining finasteride and minoxidil tablets into a topical solution that already includes Garnier Fructis stemoxydine and CB0103. They are seeking advice on whether this combination is effective and safe.

      community GT20029 Anageninc Market Availability

      in Research/Science  168 upvotes 3 years ago
      The conversation discusses the potential market release of a hair loss treatment called GT20029 by Anageninc, with users expressing interest and discussing the importance of safety and effectiveness. Some users plan to contact Anageninc to show demand for the product.

      community Oral minox + dut

      in Research/Science  8 upvotes 5 years ago
      The conversation discusses hair loss treatments using oral minoxidil, oral dutasteride, and mesotherapy dutasteride, showing impressive 6-month results. The user wishes these treatments were available in the U.S.

      community Female male-pattern AGA- seeking help

      in Female  1 upvotes 2 years ago
      A female with male-pattern hair loss (AGA) is seeking help after unsuccessful treatments with spironolactone and supplements, and is considering oral minoxidil and finasteride despite concerns about medication side effects. She has ruled out hormonal birth control and PRP/PRFM, and is looking into further medical advice due to abnormal lab results.

      community P-1075: a BETTER version of Minoxidil

      in Research/Science 5 months ago
      P-1075 is a more potent hair growth agent than Minoxidil, but it poses significant heart risks, making it unsafe for use. Despite promising results in macaques, concerns about its cardiotoxicity in rats have halted its development.