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690-720 / 1000+ resultscommunity Shower thought: at least this might be the last year we don't have Phase 2 results.
New hair loss treatments, including Breezula, VDPHL01, and PP405, are nearing Phase 3 trials, offering hope for effective solutions. Current treatments like finasteride and minoxidil remain effective, but early intervention is crucial.
community Topical finasteride (P-3074) inhibits scalp DHT up to 70%
Topical finasteride (P-3074) can inhibit scalp DHT by up to 70%, with some users experiencing systemic absorption similar to oral use. Users discuss varying application frequencies and concentrations, with some noticing side effects when overused.
community Thinking of crushing bicalutamide/spiro or any other test suppressant in my topical fin min mix. What do yall think?
The conversation is about adding crushed bicalutamide or spironolactone to a topical mix with finasteride and minoxidil to suppress testosterone in hair follicles, similar to what RU58841 does. The user cannot obtain RU58841 in their country and is seeking advice on this alternative approach for hair loss treatment.
community Anyone immediately lose hope for gt20029 when they realised it’s developed by kintor
The conversation discusses various hair loss treatments, including minoxidil, finasteride, dutasteride, pyrilutamide, alfatrodial, and nizoral, with a focus on the potential of new treatments like gt20029 and breezula. There is optimism about novel treatments that don't have systemic effects, although skepticism remains about the effectiveness of some new drugs.
community What About my 3 months treatment of dut, min and biot
community Topical melatonin shows some promise.
community RU58841 toxic to cats like minoxidil?
RU58841's potential toxicity to cats is uncertain, similar to minoxidil. Caution is advised to prevent accidental exposure to pets.
community Increased liver enzymes from hairloss medications.
Elevated liver enzymes were reported from taking finasteride and minoxidil. The doctor advised stopping oral minoxidil and taking finasteride every other day.
community Recipe for low-dose Topical Finasteride (without Minoxidil)
A user is seeking advice on creating a Minoxidil-free topical Finasteride solution due to side effects and concerns about pets. They plan to use Isopropanol alcohol, Propylene Glycol, and distilled water to make a 0.02% solution, starting with 1ml applications.
community Making topical finasteride (without minox)
community October 2025 $120M funding round for PP405 — hype justified or too early to celebrate?
Pelage secured $120 million for PP405, a non-hormonal topical hair loss treatment, sparking debate on its potential as a breakthrough. Concerns about finasteride's side effects persist, with some suggesting alternatives like topical finasteride or dutasteride.
community What can I use to prepare a lotion that doesn't irritate my scalp or make my hair sticky? (Want to experiment with metformin and Alpha Keto glutarate)
The conversation is about a user who tried dissolving a metformin pill in water for hair treatment but faced issues with hair sticking together. The user is seeking advice on preparing a non-irritating, non-sticky lotion at home, possibly experimenting with metformin and Alpha Keto glutarate.
community Xeljanz medication for alopecia universalis?
community Found a slide summary for PP405
PP405 shows promise in stimulating new terminal hair growth by activating dormant follicles, with no systemic adverse effects observed in a short-term trial. However, long-term efficacy remains unproven, and further trials are needed to confirm its potential as a hair loss treatment.
community concentration of my finasteride therapy
The conversation discusses a topical finasteride therapy with hydrocortisone butyrate, estrone base, and breviline. A user suggests oral finasteride as a superior option.
community Concerns About Combo Spray (Fin, Min, Ketoconazole) for Sensitive Scalp
The conversation is about concerns over using a combination spray containing finasteride, minoxidil, and ketoconazole for hair loss. The user is worried about potential scalp irritation and considers using separate products to better manage sensitivity.
community Latest news about pp405 (source: Christina Weng's Instagram channel)
A new hair loss treatment, pp405, may regrow hair better than finasteride and minoxidil, with potential availability by 2028. However, there is skepticism about its effectiveness and commercialization timeline.
community Does Apple cider vinegar interfere with oral minoxidil or finasteride?
Apple cider vinegar, when taken as 1 tablespoon diluted with water daily, does not interfere with the absorption of oral minoxidil or finasteride.
community Finasteride and Folic acid correlation?
Low folic acid may worsen side effects of finasteride. Consult a doctor for personalized advice.
community Is Stemoxydine and Minoxidil together in one solution ok ?
community I’m taking Veradermics VDPHL01 - AMA
A participant using Veradermics VDPHL01, an extended-release oral minoxidil, experienced significant hair regrowth from Norwood 6 to Norwood 3V without side effects. They plan to use dutasteride after the treatment to maintain results.
community New Latanoprost-Based Formula Used by Hollywood Celebrities
A new Latanoprost-based formula used by Hollywood celebrities to treat hair loss, with the formula containing minoxidil, tretinoin, melatonin, azelaic acid, zinc thymulin, vitamin B6, sandalore and methyl vanillate. It also mentions the potential of offering a combined sublingual minoxidil/oral dutasteride option in the future.
community Before Oral Minoxodil vs 3 months (2.5)
The user is using 2.5mg oral minoxidil and Nizoral shampoo for hair regrowth, noticing some improvement. They are considering increasing the dosage and exploring alternatives to topical minoxidil/finasteride due to concerns about toxicity to cats.
community tretinoin for hairloss and balding
community Kintor Pharma Announces Completion of Patient Enrollment in Phase II Clinical Trial of GT20029 for Treatment of Androgenetic Alopecia in China
Kintor Pharma completed patient enrollment for a Phase II trial in China for GT20029, a potential new treatment for hair loss. Some believe GT20029 could replace finasteride if effective, while others discuss finasteride's limited efficacy and potential underreported side effects.
community Alcohol-free minoxidil available in Europe
Alcohol-free minoxidil options in Europe, particularly from a German pharmacy, are recommended for those with seborrheic dermatitis. Users suggest alternatives like Alopexy and Doppelherz foam, and emphasize avoiding propylene glycol and alcohol to reduce irritation.
community What treatment should I take? and is it really bad?
OP is experiencing significant hair loss despite GFC and PRP treatments and has abnormal lab results. They are advised to consult a hair-focused dermatologist for further evaluation.
community I think I am recovering from Saw Palmetto side effects!!!
The user experienced negative side effects from saw palmetto, including low libido and energy, and found some improvement after using Maca and Acetyl L-Carnitine. They emphasize lifestyle changes and positivity for recovery, while expressing caution about saw palmetto's side effects.
community Steroid injections helped my hair loss but I have AGA?
A woman with AGA and CTE has been taking multiple hair loss treatments including spironolactone, dutasteride, finasteride, bicalutamide, birth control, and minoxidil without success. Steroid injections, however, dramatically and immediately stopped her hair loss, though the effect lasts less than a month.