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      community Anyone shift to dut gel cap after tablet didn't work?

      in Research/Science  1 upvotes 4 months ago
      The user experienced worsening hair loss despite using dutasteride tablets and is considering switching to dutasteride gel capsules due to concerns about tablet bioavailability. Another user mentioned that countries like Japan, Korea, and India use the tablet form, suggesting the form may not be the issue.

      community Charcoal / Ketoconazole / Caffeine shampoo

      in Treatment  4 upvotes 6 months ago
      Mixing charcoal, Ketoconazole, and caffeinated shampoo is questioned for potential interaction, specifically if charcoal inactivates other ingredients. Charcoal is used for seborrheic dermatitis, while caffeine is thought to improve scalp blood flow.

      community Fuzzy Feeling To Scalp?

      in General  60 upvotes 1 year ago
      The user has been taking oral finasteride for 2 months, experiencing more hair loss but noticing some fuzzy hair growth on the scalp. They are questioning if this new hair growth is significant.

      community tressless users after the first dose of finasteride

      in Satire  271 upvotes 2 years ago
      The conversation is a humorous take on someone's reaction after their first dose of finasteride for hair loss. Specific treatments mentioned include scalp massage and a protocol of manifestation twice daily.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community Thoughts on this 2-deoxy-D-ribose Topical?

      in Treatment  27 upvotes 1 year ago
      The post and conversation are about skepticism towards a new hair loss treatment containing 2-deoxy-D-ribose, copper peptides, and exosomes, with concerns about the legitimacy of the product and its website. The treatment's effectiveness and authenticity are questioned due to lack of testing and transparency.

      community Finasteride sleep related advice

      in Finasteride/Dutasteride  9 upvotes 4 months ago
      Finasteride can cause sleep disturbances, but these often improve over time. Some users experience side effects like reduced libido and brain fog, while others see hair regrowth and manage side effects by adjusting dosage or switching to topical treatments.

      community Openminded Creatine Discussion

      in Product  10 upvotes 9 months ago
      Creatine may cause hair shedding in some individuals, particularly those with genetic sensitivity to hair loss, but this is not universally experienced. Finasteride users report mixed results, with some experiencing resumed shedding when taking creatine.

      community Itchy/Sore scalp with hair loss M(28).

       3 upvotes 9 years ago
      A 28-year-old male is experiencing hair loss, itching, soreness, and numbness on the scalp, with symptoms including dry, brittle hair and scalp irritation. Treatments tried include Nizoral, salt water, various oils, and antihistamines, with limited success; a chemist suggested a possible fungal infection, while a doctor suspected male pattern baldness.

      community Why is no one pointing out dandruff as the number 1 evidence/symptom of MPB?

      in Chat  55 upvotes 2 years ago
      The post discusses the theory that persistent dandruff in areas prone to hair loss could be a sign of hair follicles dying due to DHT, indicating balding. The responses vary, with some users noting improvements in dandruff and hair loss with treatments like Dutasteride, while others experienced hair loss without dandruff.

      community My experience with Pyrilutamide

      in Update  43 upvotes 3 years ago
      Two different experiences of using Pyrilutamide, a hair loss treatment, which caused headaches that took around a week to subside in both cases. Other users offered insight into their own experiences with the treatment or suggested alternate treatments such as RU58841 and Minoxidil.

      community Hair feels like hay/brittle and slow growing some areas

      in General  138 upvotes 1 year ago
      The user is experiencing hair thinning and brittleness, possibly due to Telogen Effluvium, which affects body hair and may be linked to stress or nutrition. They are considering using finasteride for treatment but are unsure if it will address their symptoms.

      community Looks like fin nuked my hair 1mg ED

      in Progress Pictures  47 upvotes 2 months ago
      Finasteride can cause initial hair shedding, which may indicate effectiveness, with improvements seen after 12-24 months. Some users enhance results by combining it with minoxidil and dermarolling.

      community What's the deal with verteporfin?

      in Research/Science  23 upvotes 2 years ago
      The conversation discusses verteporfin as a potential hair loss treatment and questions why more precise methods aren't used to test its effectiveness in regrowing hair. Some users believe verteporfin is promising and should receive more attention, while others are skeptical about the testing methods.

      community What is your stack and what is your protocol for it?

      in Chat  18 upvotes 2 years ago
      A user maintains NW2 hair with 1mg finasteride, 2.5mg oral minoxidil, and 5% topical minoxidil twice daily, along with ketoconazole shampoo and derma stamping. They seek advice on more aggressive treatments to achieve NW1.
      Do you think i catch it in time?

      community Do you think i catch it in time?

      in Journals / Progress Pictures  70 upvotes 1 year ago
      A 25-year-old noticed thinning hair at the temples and started using finasteride (1mg/day) for two months, along with keto shampoo twice a week and vitamins like vitamin D, biotin, and zinc. They are seeing some results and are hopeful about regaining lost hair.

      community Any long term RU55841 / CB-03-01 / Eucapil users here?

      in Research/Science  9 upvotes 5 years ago
      Hair loss treatments RU55841, CB-03-01, and Eucapil were discussed, with concerns about needing increased dosages over time and potential side effects. A user suggested that CB's results could be due to various factors and that combining it with finasteride might slow down any upregulation.

      community Has anyone used Magnesium L-Threonate ?

       70 upvotes 7 years ago
      Magnesium L-Threonate may help treat balding by reducing DKK-1 expression without affecting DHT. Users discuss its potential effectiveness and application methods, with some considering trying it topically.

      community How is verteporfin doing in trials?

      in Chat  9 upvotes 2 years ago
      The conversation is about the progress of verteporfin in hair loss trials, with users expressing curiosity about its effectiveness and updates. Specific treatments mentioned include FUE (Follicular Unit Extraction) combined with verteporfin, with one reported case of donor area regrowth after a year, and three patients being monitored post-treatment by Dr. Bloxham with monthly updates on YouTube.

      community u/joaopassos4444 has zero education in endocrinology, human biology or science, it’s incredibly unlikely he good Will Hunting-ed a medical issue that stumped researchers for thousands of years, please stop buying random supplements based on layman speculation and temper your expectations

      in Research/Science  69 upvotes 5 years ago
      User questions credibility of a hair loss "cure" found by a non-expert and warns against wasting money on unproven supplements. Others discuss trying natural extracts and the importance of researching the enzyme 3ADH for potential hair growth benefits.