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      community The three stages of a man's life...

      in Satire  853 upvotes 2 years ago
      The conversation is about men discussing their experiences with hair loss and their acceptance or resistance to it, mentioning treatments like finasteride and hair transplants. Some users express hope to maintain their hair while young, while others have accepted baldness or found confidence after shaving their heads.

      community isoflavones to combat gyno?

      in Finasteride/Dutasteride  4 upvotes 5 years ago
      Isoflavones from soybeans may help limit estrogen's effects on the body, potentially preventing gyno. However, surgery is the only way to remove gland enlargement.

      community Is it possible to have low scalp vascularity??

      in Treatment  3 upvotes 1 year ago
      The user is using topical dutasteride, finasteride, minoxidil, and tretinoin but seeing no results or side effects. They also microneedle every two weeks but experience little bleeding, questioning if a thick scalp is preventing treatment effectiveness.

      community Unexpected Hair Growth

       6 upvotes 8 years ago
      A 24-year-old male experienced unexpected hair growth and improved skin and nails after adding daily vegetable juices, including carrot, spinach, celery, and beet, to his diet. He is not using any other treatments like minoxidil, finasteride, or RU58841.

      community any news about DUPA (Diffuse unpatterned alopecia)?

      in Research/Science  9 upvotes 3 years ago
      The conversation discusses diffuse unpatterned alopecia (DUPA) and its possible causes, including sensitivity to DHT, not being androgenic alopecia, being diffuse alopecia areata, or hormonal issues. Treatments mentioned include topical melatonin, Clobetasol Propionate for alopecia areata, and the lack of results from using finasteride, dutasteride, and minoxidil.

      community Anything stronger than DUT out there?

      in Finasteride/Dutasteride  14 upvotes 2 years ago
      The conversation discusses seeking a stronger treatment than Dutasteride (DUT) for hair loss. Suggestions include combining DUT with RU58841, increasing DUT dosage, and using transgender hormone replacement therapy or testosterone blockers, though some options may have feminizing side effects.

      community Topical Dutasteride Progress (2.5 months)

      in Is this regrowth?  3 upvotes 11 months ago
      A 21-year-old male is using a topical treatment for hair loss, including Dutasteride, Minoxidil, Tretinoin, Ketoconazole, and Hydrocortisone, along with derma rolling. He reports no side effects from the treatment and seeks feedback on its effectiveness for hair regrowth.

      community Side effects of topical azelaic acid?

      in Research/Science  5 upvotes 5 years ago
      Azelaic acid is considered a strong DHT inhibitor with no reported sexual side effects, making it a potential alternative for those who cannot use finasteride. It can be used with minoxidil, but may cause skin irritation.

      community 5 and months finasteride and microneedling

      in Progress Pictures  116 upvotes 3 years ago
      A 35 year old male who has seen good results from Finasteride and microneedling, with minimal side effects. Replies to the post ask about the device used for microneedling, discuss the progress made, and offer encouragement.

      community Targeting multiple AGA mechanisms with commonly available substances

       4 upvotes 7 years ago
      The conversation discusses using a multimodal approach to treat androgenic alopecia, including substances like gamma-linolenic acid, DHA, sulforaphane, melatonin, cetirizine, astaxanthin, fisetin, apigenin, curcumin, limonene, genistein, and berberine. Users also mention using ketoconazole, minoxidil, and low-level laser therapy (LLLT) as part of their hair loss treatment regimens.

      community Verteporfin (Visudyne) group buy 🌷

      in Treatment  28 upvotes 4 years ago
      User seeks participants for Verteporfin group buy. Verteporfin, FDA approved, may regenerate hair follicles and sweat glands through heavy microneedling.

      community Anyone else just waiting until the real pyrilutamide and then GT20029?

      in Chat  4 upvotes 2 years ago
      The user is hesitant to use finasteride due to potential hormonal side effects and is waiting for the release of pyrilutamide, a new hair loss treatment. Other users suggest trying finasteride, warning about potential regret if hair loss progresses in the meantime.

      community Atleast 30 character are requireded

      in Satire  470 upvotes 1 year ago
      The conversation humorously discusses hair loss treatments, including finasteride, minoxidil, and dermarolling, with users sharing personal experiences and side effects. Some users mention changes in hair and semen consistency, while others discuss male contraception methods.

      community What is this pigmentation around my follicles?

      in Chat  29 upvotes 1 year ago
      The conversation discusses potential causes of pigmentation around hair follicles, suggesting sebum buildup, autoimmune conditions, or dermatitis. Treatments mentioned include finasteride, dutasteride, and an anti-inflammatory diet, with a recommendation to consult a doctor for a proper diagnosis.

      community What are the alternatives to spironolactone for AGA?

      in Female  8 upvotes 1 year ago
      The user experienced side effects from spironolactone and is seeking alternatives for androgenetic alopecia (AGA), considering saw palmetto but unsure of its effectiveness. They are also exploring the possibility of using topical spironolactone, despite availability challenges.

      community Anagenic is trying to compound Gt20029

      in Treatment  57 upvotes 3 years ago
      The conversation discusses concerns that Anagenic's version of GT20029 might not be as effective or safe as Kintor's, with comparisons to issues faced by pyrilutamide. The chemical structure of the drug has been published.

      community Two of the most attractive girls I know are with NW7 guys

      in Chat  319 upvotes 10 months ago
      Bald men can still attract partners, as personality and confidence often outweigh hair loss. Treatments like finasteride and minoxidil are used, but self-acceptance and personal satisfaction are key.

      community Learn the difference between male pattern baldness and diffuse thinning, and see a doctor to diagnose which you have. Otherwise, you may waste money on HIMS 3-in-1 and risk heart or sexual side effects, just cuz a guy w/ probably biotin deficiency thinning got great results here...

      in Treatment 3 months ago
      Male pattern baldness and diffuse thinning can both be forms of androgenetic alopecia (AGA), and it's important to consult a doctor for proper diagnosis. Treatments like Minoxidil, Finasteride, and biotin are discussed, but their effectiveness varies, and side effects are a concern.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community Topical finasteride might be a lie

      in Research/Science 2 years ago
      The conversation discusses doubts about the effectiveness of topical finasteride for hair loss, suggesting that DHT could be produced elsewhere in the body and affect the scalp. It proposes that androgen receptor antagonists like spironolactone and clascoterone might be more effective as they could prevent this potential bypass mechanism.