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      Topical Dutasteride - Non-Hormonal, Side Effect Free 5ARI?

      community Topical Dutasteride - Non-Hormonal, Side Effect Free 5ARI?

      in Treatments  451 upvotes 1 year ago
      Topical dutasteride is suggested as a low side-effect treatment for hair loss, with a proposed dose of 0.025% 1ml/day. It is considered better than finasteride due to its even inhibition of DHT isoforms and lower systemic absorption.

      community What is the cause of "DHT itch"?

      in Research/Science  7 upvotes 11 months ago
      The conversation discusses the effects of using Tongkat ali and dioscorea to raise DHT levels, leading to increased body hair growth and an itchy scalp, without causing hair loss. The discussion also debates the role of DHT in male characteristics and its impact on sexual function, with differing opinions on its importance and effects.

      community [rant] being hairless is ruining all my self esteem

      in Chat  177 upvotes 1 week ago
      Hair loss is causing distress and self-esteem issues, with discussions on treatments like finasteride, minoxidil, and hair transplants. Some suggest topical treatments or lifestyle changes, while others stress the importance of confidence and self-acceptance.

      community New warning by FDA on topical finasteride

      in Research/Science  194 upvotes 11 months ago
      The FDA warned that topical finasteride can cause serious side effects like sexual dysfunction and brain fog, similar to oral finasteride. Compounded topical formulations pose additional risks due to lack of regulation.

      community stopping RU58841 while using Oral min+dut

      in Chat  1 upvotes 1 year ago
      The user is considering stopping RU58841 due to inconvenience and potential side effects, while continuing with oral minoxidil and dutasteride. Another user shared their experience of stopping RU58841 without significant hair shedding while on dutasteride and minoxidil.

      community Dutasteride at 21 years old. Is it safe?

      in Finasteride/Dutasteride  12 upvotes 2 years ago
      A 21-year-old individual questioning the safety and potential side effects of using Dutasteride for hair loss, after Finasteride and RU58841 had limited effect. The responses vary, with some users suggesting it's safe and others advising to check hormone levels before proceeding.

      community PYRILUTAMIDE PHASE 3 RESULTS : No statistical significance

      in Research/Science  126 upvotes 2 years ago
      The phase 3 trial results for Pyrilutamide showed no significant difference from the control treatment in increasing hair count, leading to the company halting its development. Users discussed their disappointment and skepticism about hair loss treatments, with some mentioning other treatments like Minoxidil, Finasteride, and RU58841.

      community Switching from Oral Minoxidil back to topical

      in Treatment  9 upvotes 1 year ago
      Switching from oral minoxidil back to topical due to heart issues and palpitations. Users discuss experiences with minoxidil and finasteride, with mixed results and concerns about side effects.

      community Dutasteride Mesotherapy or Oral Finasteride

      in Finasteride/Dutasteride  4 upvotes 5 years ago
      A user is considering dutasteride mesotherapy versus oral finasteride for hair loss, with concerns about side effects. Other users share experiences with both treatments, suggesting oral finasteride as more effective and cost-efficient, while also discussing the use of minoxidil, alfatradiol, and potential side effects like gynecomastia.

      community Topical Finasteride: 130 Day Update

      in Finasteride  9 upvotes 6 years ago
      The user tried a home-brew topical finasteride regimen for 120 days with initial benefits but no long-term improvement, leading to continued hair shedding. They switched to oral finasteride, experiencing mild testicle discomfort but no changes in libido or erections, and plan to continue this regimen for 120 days.

      community How to unocebo myself

      in Finasteride  49 upvotes 1 week ago
      The user took finasteride for a year with no issues until reading negative stories online, which led to experiencing side effects they believe are psychological. They stopped the medication and are seeking advice on recovering faster.

      community 1.25mg Finasteride (6times a week)

      in Finasteride/Dutasteride  3 upvotes 2 months ago
      A 25-year-old is using 1.25mg finasteride six times a week and 5% topical minoxidil daily for hair loss. They are experiencing reduced libido and erectile issues, possibly due to stress, and are questioning if the finasteride dosage is affecting DHT suppression.

      community Is anyone experiencing facial aging with Minoxidil.

      in Minoxidil  8 upvotes 3 years ago
      The post and conversation discuss whether Minoxidil causes facial aging, with some users reporting no side effects and attributing negative effects to possible allergic reactions. The original poster suggests more research is needed to confirm any connection between Minoxidil and facial aging.

      community Dutasteride absolutely nukes hair DHT

      in Finasteride/Dutasteride  486 upvotes 9 months ago
      Dutasteride significantly reduces DHT levels, potentially more effectively than finasteride, and is used to treat hair loss. Some users report side effects like reduced libido and mood changes, while others experience hair regrowth and increased testosterone.

      community Low dose spiro with 5ARI inhibitor

      in Chat  2 upvotes 1 year ago
      Spironolactone, finasteride, and dutasteride are discussed for hair maintenance, with concerns about testosterone and side effects like gynecomastia. Spironolactone is noted for use in both bodybuilding and hormone therapy, with low doses considered for minimizing side effects.

      community Minoxidil: How It Changes the Scalp Hormone Environment

      in Research/Science  80 upvotes 1 month ago
      Minoxidil increases blood supply to the scalp, strengthening dormant follicles and extending the growth phase, but may increase scalp activity that can be countered with DHT blockers. Women experiencing side effects from finasteride or dutasteride for hair loss might consider alternatives like estrogen, especially if on birth control.