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      community (Serious) News and discussion on potential treatments

      in Treatment  29 upvotes 1 year ago
      Current hair loss treatments include finasteride, dutasteride, minoxidil, and derma rolling. New treatments like TDM-105795, GT20029, and others show promise but require more testing and time before approval.

      community Found a slide summary for PP405

      in Research/Science  36 upvotes 3 weeks ago
      PP405 shows promise in stimulating new terminal hair growth by activating dormant follicles, with no systemic adverse effects observed in a short-term trial. However, long-term efficacy remains unproven, and further trials are needed to confirm its potential as a hair loss treatment.

      community A Technical Question About Pyrilutamide

      in Research/Science  5 upvotes 2 years ago
      Pyrilutamide is believed to be more effective than RU58841 and 1 mg finasteride in treating hair loss, with no systemic hormonal effects and the potential to block more than 31% of scalp DHT. It may also antagonize scalp testosterone due to its action as an androgen receptor antagonist.

      community My hair transplant journey at Eugenix.

      in Update  138 upvotes 4 weeks ago
      A user shared their positive experience with a hair transplant at Eugenix in India, noting the professionalism and natural results. They mentioned using 2815 grafts and discussed the clinic's controversial name, but did not mention using specific treatments like Minoxidil or finasteride.

      community Micro needling has made my hairline worse?

      in Microneedling  4 upvotes 1 year ago
      The user has been microneedling at 0.25mm once a week for 4 weeks and noticed further hairline recession. They are concerned about the impact of vitamin deficiencies, like biotin, on hair growth.

      community Has anybody tried RU58841 and pyrilutamide together?

      in Chat  9 upvotes 8 months ago
      RU58841 and pyrilutamide are being discussed as potential hair loss treatments, with some users reporting side effects. There is interest in these treatments as alternatives to 5ar inhibitors and oral minoxidil due to concerns about safety and side effects.

      community Does an increase in testosterone increase hairloss?

      in Chat  7 upvotes 2 years ago
      Finasteride and minoxidil are effective for hair growth, but increasing testosterone, even naturally with ashwagandha, may increase DHT, potentially affecting hair loss if predisposed to male pattern baldness. Testosterone replacement therapy (TRT) can be beneficial for energy and muscle gain but may expedite hair loss if already prone to it.

      community induce goosebumps to reverse hairloss

      in Satire  18 upvotes 8 months ago
      The conversation humorously discusses inducing goosebumps to potentially reverse hair loss, with mentions of using cold therapy and muscle exercises. It also references other unconventional ideas like removing a testicle to lower DHT.

      community Questions about dutasteride, minoxidil and nuclear option?

      in Minoxidil  4 upvotes 4 years ago
      The user discussed their experience with hair loss treatments, including finasteride, RU58841, Nizoral, supplements, dermarolling, and minoxidil, which caused significant edema. They also experimented with dutasteride, which led to increased hair loss, and found that Armodafinil reduced minoxidil-related water retention and hair shedding.

      community Maxogen-X progress log

      in Minoxidil  5 upvotes 5 years ago
      The user tried various hair loss treatments, including Maxogen-X, Dualgen15, minoxidil, finasteride, and dermarolling, but experienced limited regrowth and some side effects. They eventually switched to oral minoxidil, hoping for better results.

      community Genetics are so weird and unpredictable

      in Minoxidil  118 upvotes 1 year ago
      The user experienced male pattern baldness starting at 18, tried finasteride with no success, and switched to dutasteride, which halted hair loss. Minoxidil had no effect for them, while their brother, who didn't use AR inhibitors, maintained a juvenile hairline and successfully grew a beard with minoxidil, highlighting the unpredictable nature of genetics in hair loss and treatment response.

      community The Hormonal Profile of MPB/AGA

      in Research/Science  9 upvotes 4 years ago
      Men with early male pattern baldness (MPB) may have hormonal abnormalities similar to those in women with PCOS. Specific treatments mentioned include Minoxidil, Finasteride, and RU58841.

      community PP405 - A True Breakthrough or Another Disappointment?

      in Research/Science  34 upvotes 9 months ago
      PP405 shows potential for hair growth, with 31% of advanced balding men experiencing over 20% increase in hair density in 8 weeks. However, skepticism persists due to selective data presentation and lack of long-term results, with comparisons to treatments like minoxidil and finasteride.

      community Since there is so much hype for cosmeRNA and HMI-115...

      in Chat  47 upvotes 3 years ago
      Exploring different treatments for hair loss, such as cosmeRNA and HMI-115 which are small interference messenger RNA that inhibits the DHT receptor and an antibody that binds to the prolactin (PRL) receptor respectively; and researching mechanism and environment of hyperresponders.

      community Finasteride , creatine and muscle growth

      in Finasteride/Dutasteride  27 upvotes 1 year ago
      Finasteride does not significantly affect muscle gains and can slightly increase testosterone levels. Creatine is generally considered safe to use with finasteride, though some believe it may increase DHT levels, potentially affecting hair loss.

      community Anagenic replied on availability of gt20029

      in Product  19 upvotes 3 years ago
      The conversation is about the availability of gt20029 for hair loss treatment, indicating that it will not be available for purchase soon. No specific treatments were discussed.

      community When is GT20029 going to come out?

      in Research/Science  40 upvotes 1 year ago
      The conversation discusses the anticipation and skepticism around the release of GT20029 for hair loss treatment. The original poster has been using Finasteride and Minoxidil but is hopeful for GT20029, while others express doubts about its timely release and suggest alternatives like KX826 and hair transplants.

      community PP405 Hairloss Reversal and Hairline Restoration

      in Treatment  5 upvotes 2 months ago
      PP405 may induce new hair growth but cannot revive completely dead follicles, and its effectiveness on hairlines is uncertain. It is expected to be available by mid-2028, but users are advised to manage expectations and consider using other treatments like minoxidil and finasteride.

      community AGA evaluation and first steps - BEGINNER MEGAPOST

      in Chat  79 upvotes 1 year ago
      The conversation discusses androgenic alopecia (AGA) and its treatments, focusing on finasteride, minoxidil, and ketoconazole shampoo. Finasteride is recommended as essential for preventing further hair loss.