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community Pelage PP405: New Hair Growth from Inactive Follicular Units - Phase 2a results at AAD 2026

in Research/Science 1067 upvotes 2 months ago

PP405, a topical treatment, shows promise for hair growth by activating inactive follicles, with 66% of participants experiencing positive results. The treatment is well-tolerated and may proceed directly to Phase 3 trials, offering a potential alternative to minoxidil and finasteride.

community Increasing GH and IGF-1 for Increased Growth/Reduced Hair Loss?

in Research/Science 4 upvotes 2 years ago

Increasing IGF-1 may help hair growth, but it could also increase hair loss in people with high testosterone. Treatments discussed include l-arginine, glutamine, vanadium, Deer Antler Velvet, ATP, Cocarboxylase, l-carnitine, and Mk677.

community Anyone who used topical bicalutamide/estradiol/cyproterone acetate /spironolacton? (Need advice)

in Treatment 6 upvotes 1 year ago

A user is seeking advice on the efficacy and side effects of homemade topical solutions for hair loss, specifically bicalutamide, estradiol, cyproterone acetate, and spironolactone, as they cannot access RU58841 or pyrilutamide.

community Testosterone in Reference Range Doesn't Cause Hair Loss

in Research/Science 53 upvotes 2 years ago

Testosterone within the normal range does not significantly contribute to male pattern baldness (MPB); DHT is the main factor that can be controlled. Genetics play a crucial role in hair loss, and treatments like finasteride and dutasteride, which block DHT, can help despite potentially raising testosterone levels.

community Correlation between topical retinoids and diffuse hair loss

in Research/Science 6 upvotes 4 years ago

Excess Vitamin A and topical retinoids can cause diffuse hair shedding. The user suspects their chronic telogen effluvium may be linked to using adapalene, a topical retinoid.

community Pyrilutamide update number 1 - 1 week use

in Update 55 upvotes 3 years ago

A user who is using Pyrilutamide, Finasteride, and a homemade topical solution to treat their hair loss. Replies mentioned the potential of Pyrilutamide being a "cure" for hair loss and a reminder that results may not be credited solely to it.

community Can Whey Protein isolate make your AGA worse?

in Product 9 upvotes 3 years ago

Whey protein isolate may worsen androgenetic alopecia (AGA) due to its potential to increase DHT levels, but finasteride use has helped maintain hair. Some users suggest avoiding protein supplements due to possible contaminants and additives that could affect hair health.

community Prevent g thinning while promoting beard growth

in General 61 upvotes 1 year ago

A 25-year-old male experiencing hair shedding due to testosterone use is considering topical finasteride or RU58841 for scalp treatment while continuing minoxidil for beard growth. Topical finasteride is suggested to prevent scalp thinning without affecting beard growth.

community Has anyone got results from pyrilutamide?

in Research/Science 3 upvotes 6 months ago

The user maintained hair with minoxidil, alfatradiol, and fluridil after stopping finasteride due to erectile dysfunction. They recently added pyrilutamide and are seeking feedback on its effectiveness after six months of use.

community Betamethasone dipropionate 0.05 (sernivo spray)

in General 76 upvotes 1 year ago

A user was prescribed betamethasone dipropionate spray for a receding hairline, which caused skin peeling and depigmentation. They stopped using it and are considering alternatives like BPC-157/TB-500 for healing.

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