The conversation discusses hair loss treatments, specifically Minoxidil, finasteride, and RU58841. It also inquires about the timeline for the GT20029 phase 3 trial by Kintor.
Pyrilutamide and RU58841 are androgen receptor antagonists that block receptors without significantly reducing testosterone or DHT levels. Any indirect effect on androgen levels is likely negligible.
A 21-year-old is using oral minoxidil, rosemary oil, saw palmetto, and pumpkin seed oil for hair regrowth but is advised to use finasteride or dutasteride for better results. The user is hesitant to use DHT blockers due to cost and is seeking advice on whether their current regimen is effective.
The user reported noticeable hair regrowth after using dutasteride 0.5 mg, oral minoxidil 2.5 mg daily, and ketoconazole shampoo weekly for six months. They are considering adding RU58841 for further improvement.
A user asked about the difference between two brands of Dutasteride on Oxford Online Pharmacy. Replies indicated no difference besides the brand name, and one user found Dutasteride more effective than Finasteride.
A 36-year-old male using dutasteride and minoxidil has seen significant hair regrowth, confirmed by a dermatologist and supported by before-and-after photos. He plans to increase his oral minoxidil dosage and add dermapen to his routine.
The user is seeking alternatives to propylene glycol and glycerin for mixing with RU58841 due to allergies and greasiness. Suggestions include reducing glycerin and considering stemoxydine as a solvent.
The post expresses frustration over the unavailability of pure topical finasteride in India despite the developed pharma industry. The user seeks advice on making it at home and its effectiveness.
A user is considering starting spironolactone for hair loss without consulting a dermatologist, as previous dermatologists only recommended biotin, vitamins, or PRP. The user notes that spironolactone is affordable in their country.
Dr. Toyos is recruiting more participants for a larger trial on hair loss treatments. The discussion mentions Minoxidil, finasteride, and RU58841 as potential treatments.