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      community Chat is this real? Compound called clascoterone

      in Research/Science  588 upvotes 4 months ago
      Clascoterone shows promising results for hair regrowth in men with androgenetic alopecia, with potential FDA approval by 2026. It acts as a topical androgen receptor blocker, offering a new treatment option with minimal side effects compared to existing treatments like finasteride.

      community Possible natural pp405 solution

      in Research/Science  45 upvotes 7 months ago
      Rotenone, a natural plant extract, may promote hair growth by increasing LDH activity and blocking MPC in the scalp, but it carries risks due to its toxicity. The suggested formulation includes Barbasco extract, DMSO, propylene glycol or PEG-400, ethanol, and a carrier oil.

      community Regimen proposal (incl. dut meso) (event industry)

      in Finasteride/Dutasteride  1 upvotes 8 months ago
      A user in their early 20s is concerned about minor hair thinning and is considering a hair loss regimen involving PRP sessions, mesotherapy with dutasteride injections, and low-dose finasteride. They dislike minoxidil due to its greasiness and prefer a routine that is easy to maintain.

      community Musely's topical hair solution

      in Finasteride/Dutasteride  6 upvotes 3 years ago
      The conversation discusses a topical hair loss treatment containing 0.1% dutasteride, 6% minoxidil, tretinoin, and ketoconazole. The user is asking for opinions on the effectiveness of this solution.

      community Anageninc RU58841 is legit & my experience

      in Research/Science  7 upvotes 2 years ago
      The user experienced side effects from RU58841, including dry eyes and potential eyesight issues, and decided to stop using it. They confirmed the product's legitimacy but advised caution due to its experimental status and lack of safety data.

      community Question about RU58841 in minoxidil

      in Minoxidil  5 upvotes 5 years ago
      The user is considering adding RU58841 to liquid minoxidil without propylene glycol (PG) due to an allergy and is asking if this combination is effective and if PG is necessary. They have been using finasteride and minoxidil foam, plan to use RU58841 with liquid minoxidil in the evening, and continue finasteride.

      community Tretinoin absorption Minoxidil

      in Treatment  2 upvotes 1 year ago
      Tretinoin may help more minoxidil convert to its active form and could potentially increase its absorption, raising concerns about safety if too much enters the bloodstream. It's unclear if tretinoin affects finasteride absorption.

      community Earliest we can get legitimate pyrilutamide

      in Research/Science  48 upvotes 3 years ago
      Pyrilutamide, a drug in phase 3 trials in China, potentially becoming available in late 2023 or early 2024; Finasteride being used as a current treatment for hair loss; and the possibility of joining a group buy for black market versions of Pyrilutamide.

      community Tretinoin can make it worse!!!

      in Chat  7 upvotes 2 years ago
      Tretinoin may enhance minoxidil's effectiveness for those not responding to minoxidil alone, but it could reduce efficacy for some who are already responding to minoxidil. Tretinoin requires careful use, including skin moisturizing and sun protection due to increased sensitivity.

      community Using Topical Minoxidil And Pyrilutamide Together

      in Treatment  1 upvotes 1 year ago
      Mixing 1ml of topical Minoxidil and Pyrilutamide (2ml total) together in a container and applying immediately is being discussed. The concern is whether this method degrades or compromises the efficacy of either compound.

      community Fevipiprant 2019!

       15 upvotes 9 years ago
      The conversation discusses Fevipiprant, an asthma drug that may block CRTH2 and potentially stop male pattern baldness (MPB) without inhibiting DHT. It also mentions the use of finasteride and dutasteride for hair loss.

      community Topical tretinoin increases minoxidil absorption by 3x. Thoughts?

      in Minoxidil  37 upvotes 7 years ago
      Topical tretinoin can increase the absorption of minoxidil by three times, which may enhance its effectiveness for hair loss treatment. Tretinoin causes increased skin turnover, making the skin more permeable and potentially improving minoxidil's efficacy.

      community Pyrilutamide 4 Month Journey with progress Pics..!!!

      in Progress Pictures  21 upvotes 8 months ago
      The user reported significant hair regrowth and stopped hair loss after using Pyrilutamide and Minoxidil for four months. They found Pyrilutamide effective in blocking DHT locally without side effects, preferring a gray market version over Koshine's product.

      community Simple to add GHK-Cu to RU58841?

      in Product  1 upvotes 1 year ago
      The conversation is about a user seeking advice on adding GHK-Cu to RU58841 for hair loss treatment, while already using oral minoxidil, dutasteride, ketoconazole shampoo, and considering LLLT. They are unsure about the concentration and carrier solution for GHK-Cu.

      community Difference: GT20029 vs CosmeRNA

      in Treatment  9 upvotes 3 years ago
      GT20029 and CosmeRNA are both potential hair loss treatments; GT20029 breaks down the androgen receptor, while CosmeRNA prevents its production. Continuous use is needed, but less frequently than current treatments like Minoxidil and Finasteride.

      community CRAZY HIGH? 1% Fin 0.3% GHK-CU topical perscription

      in Treatment  2 upvotes 1 month ago
      The conversation discusses concerns about using a high concentration of 1% topical finasteride for hairline balding, with some users suggesting starting with a lower dose. It also mentions the use of GHK-CU peptide and the importance of considering the formulation to avoid excessive absorption.

      community MinoxidilMax just launched a 0.3% tretinoin topical. Would you try?

      in Treatment  14 upvotes 4 years ago
      The conversation discusses a new 0.3% tretinoin topical launched by MinoxidilMax for mixing with other solutions, with some users expressing concern about potential skin irritation compared to lower concentrations. MinoxidilMax has also released other products like topical Dutasteride and RU58841.

      community Best brand of topical melatonin?

      in Product  8 upvotes 3 years ago
      People are using topical melatonin for diffuse thinning and retrograde alopecia. They are discussing the best brands and application methods.

      community Formula 82M?

      in Question  4 upvotes 7 years ago
      Formula 82M, a minoxidil and retinol liquid, improved hair texture and filled in temples with baby hairs for the user, but its high cost and lack of reviews cause concern. Another user mentioned using a similar product, 82F, which has become less effective and expensive over time.

      community Do we have anything in the pipeline that is used as a replacement for minoxidil?

      in Minoxidil  17 upvotes 1 year ago
      The conversation discusses hair loss treatments, focusing on alternatives to Minoxidil, such as Bimatoprost and Latanoprost, and the use of Finasteride, Dutasteride, RU58841, and microneedling. The user plans to add Latanoprost to their regimen, which already includes oral and topical Minoxidil and Finasteride, Ketoconazole shampoo, and microneedling.

      community Proposed new pathogenesis model for androgenetic alopecia (AGA)

      in Research/Science  6 upvotes 2 years ago
      The conversation discusses a new model for understanding androgenetic alopecia (AGA), linking it to dietary and lifestyle factors similar to PCOS, and highlighting the role of DHT, vascular damage, and inflammation. Treatments mentioned include Minoxidil, finasteride, and RU58841.

      community My experience with Pyrilutamide

      in Update  43 upvotes 3 years ago
      Two different experiences of using Pyrilutamide, a hair loss treatment, which caused headaches that took around a week to subside in both cases. Other users offered insight into their own experiences with the treatment or suggested alternate treatments such as RU58841 and Minoxidil.