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      community Why is there no feedback on pge2/setipiprant?

      in Question  5 upvotes 9 years ago
      The conversation questions the lack of feedback on the effectiveness of PGE2 and setipiprant for hair loss, despite their availability. The user is puzzled by the absence of reviews or results, whether positive or negative.

      community Take licorice to lower testosterone?

      in Question  1 upvotes 9 years ago
      Licorice is not recommended for hair loss as it inhibits hair growth and is a non-selective testosterone inhibitor. Alternatives like spironolactone are suggested for those considering hormonal treatments for hair loss.

      community Is regrowth normally painfully slow?

      in Treatment  5 upvotes 2 years ago
      The user is experiencing slow but solid hair regrowth using topical finasteride, oral minoxidil, keto shampoo, microneedling, RU58841, and rosemary oil. Another user suggests being grateful for the dense coverage.

      community Going to start the sulforaphane experiment

      in Treatment  17 upvotes 4 years ago
      A user shared their experience with hair loss treatments, including minoxidil and finasteride, and their negative side effects. They outlined a new treatment plan involving microneedling, various supplements, minoxidil foam, ketoconazole shampoo, and an anti-inflammatory diet, with plans to document progress over three months. Another user responded, indicating their own similar efforts were a waste of money.

      community Am I a Hyper Responder or is this Normal Growth

      in Is this regrowth?  40 upvotes 1 year ago
      The user experienced significant hair regrowth in 5 weeks using Minoxidil, Finasteride, Dutasteride, biotin, collagen, derma stamping, and a mixture of oils, leading others to label them a "hyper responder." Some users advised caution with microneedling frequency to avoid potential scarring.

      community Current regimen without fin/min

      in Treatment  5 upvotes 4 years ago
      The conversation discusses a hair loss regimen using natural oils like pumpkin seed, rosemary, peppermint, evening primrose, and sea buckthorn, along with microneedling, niacin, vitamin B complex, and astaxanthin. Some users criticize the effectiveness of this approach compared to treatments like finasteride and minoxidil, while others suggest adding saw palmetto and other supplements.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community Does the PG-free version of RU58841 have lower absorption compared to the PG version?

      in Chat  6 upvotes 10 months ago
      The conversation discusses the absorption and effectiveness of PG-free versus PG versions of RU58841, with some users believing PG improves efficacy while others see no difference. Concerns about RU58841's potential side effects on the endocrine system are also mentioned, with one user considering switching to pyrilutamide.

      community Hormone tests to decide on oral fin

      in Finasteride/Dutasteride  4 upvotes 1 year ago
      The conversation discusses starting low-dose oral finasteride for hair loss, considering hormone levels and potential side effects like gynecomastia. Suggestions include using DIM for estradiol, vitamin B6 for prolactin, and lifestyle changes to optimize hormone profiles before starting treatment.

      community Tretinoin 0.025% cream vs gel ?

      in Treatment  1 upvotes 1 year ago
      The conversation discusses the difficulty of applying tretinoin 0.025% cream on the scalp and considers switching to a gel for easier application. It also mentions that a liquid solution, ideally combined with minoxidil, may be more effective for hair treatment.

      community PG causing irritation when applying RU

      in Research/Science 3 years ago
      The user is experiencing irritation from using PG with RU58841 and is seeking alternative solutions like K&B in the UK. They report redness, itchiness, and flaky skin from the current treatment.

      community Experiment with Growth Factors and Microneedling

      in Microneedling  5 upvotes 10 months ago
      The conversation is about experimenting with microneedling and growth factor topicals for hair growth, avoiding Minoxidil due to shedding concerns. The treatment includes microneedling, growth factor topicals, finasteride, biotin, and a caffeine shampoo.

      community Haircafe on why microneedling is bad for hair growth

      in Microneedling  157 upvotes 2 years ago
      Microneedling combined with minoxidil and finasteride shows significant hair regrowth, though opinions on its effectiveness vary. Some users report substantial benefits, while others highlight the need for more research and consistency in application.

      community Treatment of Androgenetic Alopecia: Current Guidance and Unmet Needs

      in Research/Science  3 upvotes 3 years ago
      The review discusses traditional hair loss treatments like minoxidil and finasteride, and newer options like Low-Level Laser Therapy, microneedling, and platelet-rich plasma for androgenetic alopecia. It highlights the need for more high-quality trials to assess these treatments' effectiveness and standardized protocols for emerging therapies.

      community Two Month Progress // Happy New Year

      in Progress Pictures  86 upvotes 5 years ago
      The conversation is about a person's two-month hair regrowth progress using 1mg finasteride daily, minoxidil twice most days, biotin gummies, a normal diet, moderate exercise, and scalp massages, with plans to possibly use a derma roller next. They experienced minor side effects at the start but are now using a Keeps subscription without issues.

      community Please critique my regimen, gentle approach oral/topical

      in Treatment  1 upvotes 2 years ago
      The user is taking 0.5mg finasteride and 0.5mg Loniten orally daily, using Eucapil twice weekly, and Minoxidil foam once daily for hair loss. They believe Eucapil effectively stops hair loss despite side effects like breast growth.

      community Allergan recruiting for Setipiprant trial in the US

       13 upvotes 9 years ago
      The conversation discusses a clinical trial for Setipiprant in the US, starting June 29th, with eligibility excluding recent users of minoxidil or finasteride. It encourages informed decision-making before signing up.

      community Well well well some results in

      in Is this regrowth?  222 upvotes 3 months ago
      The user experienced significant hair regrowth using a regimen of 1 mg finasteride daily, minoxidil twice daily, ketoconazole shampoo weekly, dermastamping weekly, and tretinoin. They reported no side effects and emphasized the importance of committing to the treatment.

      community Tropical growth stimulants other than minoxidil

      in Treatment  11 upvotes 2 years ago
      The conversation discusses alternative hair growth treatments to minoxidil, including Stemoxydine, Tretinoin, adenosine, Baicalin, castor oil, Latanoprost/bimatoprost, and Redensyl. Users share their experiences and opinions on the efficacy of these treatments.