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      community Topical Finasteride in India??

      in Finasteride/Dutasteride  7 upvotes 2 years ago
      The post expresses frustration over the unavailability of pure topical finasteride in India despite the developed pharma industry. The user seeks advice on making it at home and its effectiveness.

      community Kintor pyrilutamide presentation?

      in Research/Science  12 upvotes 3 years ago
      The conversation is about whether the phase 2 results for pyrilutamide, a potential hair loss treatment, were presented at a dermatology convention and inquiries about the completion of phase 3 trials. Specific treatments mentioned include pyrilutamide.

      community Is this hierarchy of topical anti androgens accurate?

      in Ketoconazole  7 upvotes 4 years ago
      User on fin, minox, and ketoconazole seeks to add another topical anti-androgen. Hierarchy of effectiveness: 1. RU55841, 2. Fluridil - Eucapil, 3. CB-03-01 - Breezula, 4. Ketoconazole; alfatradiol suggested as addition.

      community Minxodil collegen synthesis decrease?

      in Minoxidil  3 upvotes 1 year ago
      Minoxidil may age skin by slowing collagen synthesis, but using collagen peptides and a basic skincare routine might counteract this. Foam minoxidil could reduce systemic absorption and avoid alcohol-related side effects.

      community RU55481

       4 upvotes 12 years ago
      The conversation discusses using RU58841, a research chemical, for hair loss treatment. The user plans to use it due to side effects from finasteride and minoxidil, despite skepticism about its effectiveness and lack of FDA approval.

      community The real stack, the only things you really need.

      in Treatment  1 upvotes 1 year ago
      The conversation discusses a hair loss prevention regimen using a custom topical treatment with Dutasteride, Minoxidil, Latanoprost, Cetirizine, Tretinoin, Vitamin D3, and caffeine, along with supplements like iron, selenium, vitamin D, and vitamin B. The user advises against expensive treatments like LLLT caps and unnecessary natural supplements.

      community Just topical min and fin, 6 months.

      in Is this regrowth?  222 upvotes 1 year ago
      The conversation is about using a topical spray containing minoxidil, finasteride, and tretinoin for hair regrowth over six months, with positive results and minimal side effects. The user also mentions using biotin and alpecin, and discusses the benefits of topical application over oral forms.

      community Unexpected temple hair growth from GHK-Cu

      in Update  23 upvotes 5 months ago
      GHK-Cu injections led to unexpected temple hair growth for someone who had been using minoxidil and finasteride for over a decade. The user plans to continue using GHK-Cu and experiment with a DIY AHK-Cu serum.

      community Can toppik fibers cause hair loss?

      in Chat  1 upvotes 3 years ago
      Toppik fibers causing hair loss is questioned. Applying it may pull out already shed hairs, and user experiences oral minoxidil shedding.

      community My Current Stack: Every Studied Natural at Maximum Concentration

      in Treatment  1 upvotes 9 months ago
      The conversation is about a hair loss treatment regimen using high concentrations of natural ingredients: pumpkin seed oil, saw palmetto, rosemary and peppermint essential oils, and caffeine. The user also practices microneedling, scalp massage, and takes Nutrafol.

      community A 100-day transformation of shedding

      in Progress Pictures  8 upvotes 10 months ago
      OP shared a 100-day progress on reducing hair shedding using Minoxidil and Dorpang scalp serum, noting healthier hair growth. Other users discussed their own treatments, including Minoxidil, ketoconazole, saw palmetto, and pumpkin seed oil, with some considering finasteride if needed.

      community Is RU58841 or pyrilutamide a stronger topical anti-androgen?

      in Treatment  3 upvotes 4 months ago
      The conversation discusses adding either RU58841 or pyrilutamide to a hair loss treatment regimen that already includes oral dutasteride and oral minoxidil. RU58841 is considered the stronger anti-androgen but may have more side effects.

      community 3 months of min/fin + ketoconazol 2% and derma stamp 0.75mm.

      in Progress Pictures  9 upvotes 1 year ago
      The conversation discusses hair loss treatments, specifically using topical minoxidil, oral finasteride, ketoconazole, and derma stamping. Users share their experiences, with one noting improved scalp health and slight regrowth, while another considers switching treatments due to lack of progress.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community Minoxidil: Sulfotransferase Enzyme booster AVAILABLE NOW

      in Minoxidil  7 upvotes 2 years ago
      A new product, Minoxidil booster, which enhances sulfotransferase enzyme activity in the scalp, is now available. The user has started using this product, applied before Minoxidil, to improve their hair loss treatment results.

      community Dutasteride 1mg or RU58841 8% or topical Dutasteride

      in Treatment  3 upvotes 1 year ago
      The discussion focuses on hair loss treatments, with suggestions to increase oral Dutasteride to 1 mg or more, as topical Dutasteride is less effective. Other treatments mentioned include RU58841, Minoxidil, and dermastamping, with some users recommending injectable mesotherapy and topical Finasteride.

      community Minoxidil Response Test - worth it?

      in Minoxidil  9 upvotes 1 year ago
      The conversation discusses the use of topical minoxidil for hair loss and the potential benefits of taking a Minoxidil Response Test to determine enzyme activity related to its effectiveness. Some users have considered or tried alternatives like oral minoxidil or tretinoin, with mixed experiences regarding side effects and effectiveness.

      community Growth stimulants worth a damn besides minox?

      in Minoxidil  3 upvotes 2 years ago
      The user experiences side effects from minoxidil and is considering alternatives like stemoxydine and adenosine for hair regrowth and density, but finds options like caffeine and various oils unreliable. They are also using a 5AR inhibitor (finasteride).

      community Trestolone (MENT) as a nuclear treatment

      in Treatment  99 upvotes 3 years ago
      Experimenting with trestolone as a treatment for hair loss in an attempt to avoid DHT-related treatments such as finasteride and dutasteride, and discussing the potential effects of its receptor selectivity on the androgen receptors in the scalp.

      community Kintor starts a new Phase 3 for Pyri... (1+ year)

      in Research/Science  16 upvotes 2 years ago
      The conversation discusses Kintor's initiation of a new Phase 3 trial to assess the long-term safety of Pyrilutamide (KX-826) for hair loss, which will last 52 weeks. Specific treatments mentioned include Pyrilutamide.

      community I mixed ru58841 with minoxidil, help

      in Treatment  4 upvotes 1 year ago
      OP mixed RU58841 with minoxidil and noticed undissolved particles. They are seeking advice on whether it matters or how to fully dissolve it.

      community KX-826: Long-Term Safety Results are out!

      in Research/Science  157 upvotes 1 year ago
      KX-826 initially improves hair growth but declines after 24 weeks, with mild itching as a side effect. Combining it with minoxidil and finasteride may improve results, but long-term effectiveness is uncertain.

      community How to mix ru-powder with European ingredients?

      in Product  1 upvotes 2 years ago
      A user seeks advice on mixing RU58841 serum using European ingredients, specifically struggling to find propylene glycol. They are looking for alternatives to American products commonly recommended in guides.

      community Anyone here use RU for hair loss?

      in Chat  4 upvotes 5 months ago
      The conversation is about using RU58841 for hair loss, with OP currently using topical finasteride. OP is seeking experiences and advice on RU58841.

      community I had claude create a protocol only using fda approved drugs.

      in Research/Science  4 upvotes 5 months ago
      A new hair loss protocol using FDA-approved topical treatments targets eight pathways, potentially improving results by 60-75% compared to the standard 40-50% from oral minoxidil and finasteride. The protocol includes minoxidil, finasteride, tacrolimus, cetirizine, bimatoprost, lithium gluconate, losartan, melatonin, NAC, caffeine, and tretinoin, with a monthly cost of $35-50 in Mexico and $80-150 in the US.