Amplifica starting clinical trials for new hair loss drug. SCUBE3 protein discovered, stimulates hairgrowth, could be alternative to Minoxidil and Finasteride.
PP405 is moving to late-stage trials, showing potential for hair regrowth, with 31% of male patients experiencing a 20% increase in hair density. Veradermics is developing an oral minoxidil version, and there is interest in combining treatments for better results.
ET-02, a new hair loss treatment, shows promising results with a 6-fold increase in hair count, potentially outperforming minoxidil by activating stem cells in hairfollicles. Further trials are ongoing to confirm its efficacy and safety, with potential market release in the future.
A user shared a beard growth protocol involving hydration toner, azelaic acid, tretinoin, moisturizer, 5% topical minoxidil, and SPF 30+ sunscreen. The regimen spans a year to a year and a half, with specific application schedules for different phases.
Hair loss treatments discussed include Propecia, Rogaine, Nizoral shampoo, and dermarolling. Users shared experiences and results, with some noticing improvements in hairgrowth and maintenance.
The conversation discusses positive initial trial results for GT20029, a topical compound for hair loss that degrades androgen receptors, potentially requiring only weekly application. Participants express hope for this treatment to be more effective and convenient than current options like Minoxidil, Finasteride, and RU58841.
A user's father, mostly bald for 20 years, is regrowing hair using a serum called "Skrzypovita Serum Pro" without minoxidil. The user is curious about which ingredients might be causing hairgrowth.
Finasteride is more effective for long-term hair maintenance by addressing the root cause of hair loss, while minoxidil acts as a growth stimulant with faster visible results. Combining both treatments is optimal, with oral minoxidil often showing better results for some individuals.
The user underwent a hair transplant with 3500 grafts and has been using Finasteride and Minoxidil for 5.5 months, seeing some growth. They plan to have a second transplant for the crown area and are seeking opinions on future results and density improvement.
Switching milk brands cleared scalp inflammation and other symptoms, but hair shedding continues. The user hopes shedding will stop as hair cycles progress.
Kintor Pharma completed patient enrollment for a Phase II trial in China for GT20029, a potential new treatment for hair loss. Some believe GT20029 could replace finasteride if effective, while others discuss finasteride's limited efficacy and potential underreported side effects.
Sodium dodecyl sulfate, oleic acid, and palmitoleic acid may promote hairgrowth, but their safety and effectiveness for humans are uncertain. Users consider trying these treatments cautiously, exploring alternatives like ostrich oil and microneedling.
PP405 shows potential for hairgrowth by increasing terminal hair and converting vellus hairs, but results are modest and more waiting is needed. It complements existing treatments like minoxidil and finasteride, but won't replace them.
Topical sodium valproate may promote hairgrowth by inhibiting GSK3β, allowing beta-catenin to proliferate, but it has potential side effects and requires more research. The conversation also mentions skepticism about a product called Vdphlo1, which includes sodium valproate and other ingredients.
Researching the effects of scalp trauma on hairgrowth, with some users suggesting experimenting with a soldering iron or derma pen, and others bringing up studies that suggest this may be an effective treatment.
BPC-157 may promote hairgrowth by increasing angiogenesis, similar to how Minoxidil works, though no direct research confirms this yet. Users report combining BPC-157 with Minoxidil and finasteride for better results, but concerns about long-term safety exist.
PP405 shows promising results for hairgrowth, potentially outperforming finasteride without side effects like erectile dysfunction. Users discuss using treatments like minoxidil, pyrilutamide, nizoral, and alfatradiol while waiting for PP405's availability.
Minoxidil can stimulate hairgrowth but does not prevent long-term hair loss, while finasteride or dutasteride is necessary to address DHT and maintain hair. Family hair history may not predict individual outcomes, and combining treatments like microneedling can enhance results.
The post discusses whether finasteride can maintain hairgrowth stimulated by minoxidil. The response indicates that finasteride cannot sustain minoxidil-grown hairs.
PP405 shows promise in activating dormant hairfollicles and increasing hair counts but lacks detailed efficacy data compared to minoxidil and finasteride. Opinions are mixed, with some optimism and skepticism about its effectiveness.
PP405 is a new hair loss treatment targeting dormant hairfollicles, with ongoing trials. Some users consider stopping finasteride and minoxidil to join trials, while others doubt its effectiveness.
RepliCel's potential hair loss treatment may cost around $1000 and aims to protect hairfollicles from DHT, possibly reversing some miniaturization. It is not considered a cure and may be most effective in early hair loss stages, with its main advantage over finasteride being the lack of sexual side effects.
The user reported significant hairgrowth after 8 months using a topical solution of 0.25% Finasteride and 8% Minoxidil, with no side effects. They also performed micro-needling and took multivitamins.
PP405 is discussed as a potential hairgrowth stimulant, possibly more effective than minoxidil, but not a cure for hair loss. There is skepticism about its ability to regrow "deadzones," and concerns about its impact on those with hair transplants.
PP405 is in phase 2 trials for hair loss, with discussions on its cost and effectiveness compared to minoxidil and finasteride. Users are skeptical about its efficacy and timeline, with hopes for market release by 2027.
The user reported hair thickening and new growth after using minoxidil and microneedling for over three months. They are considering finasteride but have not started it yet.
A user shared their hair regrowth progress after using 1mg of finasteride daily for six months, with a break of two weeks due to knee surgery. Some suggest adding minoxidil for better results, while others discuss finasteride's effectiveness in promoting hairgrowth, which can be slower but significant.
Research and science related to a minor improvement in hairgrowth caused by the use of verteporfin, as well as potential treatments such as Minoxidil, Finasteride, and RU58841.
A 24-year-old experienced improved hairgrowth using 5% minoxidil, 1 mg finasteride, and dermastamping, but faced side effects like low libido and mild erectile dysfunction. They plan to reduce finasteride dosage after full results and may consider a hair transplant if thinning recurs.