Hairgrowth can be induced without stopping DHT, as seen with Minoxidil. HMI115 may work by promoting follicle growth, not targeting the root cause of hair loss (DHT).
Clascoterone (Breezula) shows promising hairgrowth results, but skepticism remains due to past disappointments with new treatments. It may be a good alternative for those who can't tolerate finasteride or dutasteride, and can potentially be combined with them and minoxidil for better results.
VDPHL01 shows faster and stronger hairgrowth compared to standard minoxidil, with no major side effects reported. Users discuss combining it with other treatments like dutasteride and finasteride for better results, while expressing skepticism about the effectiveness of PP405.
The user is experiencing a second hair shedding phase after 7 months on finasteride, oral minoxidil, and ketoconazole, and is concerned about the sustainability of the treatment. Others encourage continuing the treatment, explaining that shedding is normal and should stabilize over time.
The user is experiencing positive hairgrowth after 3 months using 0.5mg dutasteride, 2.5mg oral minoxidil, topical minoxidil, dermastamping, and biotin shampoo, with some side effects like reduced libido and palpitations. They plan to continue treatment for a year before considering a hair transplant, as advised by another user who suggests waiting for full results from minoxidil and finasteride.
PP405 shows potential for hairgrowth, with 31% of advanced balding men experiencing over 20% increase in hair density in 8 weeks. However, skepticism persists due to selective data presentation and lack of long-term results, with comparisons to treatments like minoxidil and finasteride.
PP405 is in phase 2 trials for hair loss, with discussions on its cost and effectiveness compared to minoxidil and finasteride. Users are skeptical about its efficacy and timeline, with hopes for market release by 2027.
The user reported hair thickening and new growth after using minoxidil and microneedling for over three months. They are considering finasteride but have not started it yet.
KX-826 initially improves hairgrowth but declines after 24 weeks, with mild itching as a side effect. Combining it with minoxidil and finasteride may improve results, but long-term effectiveness is uncertain.
Chime Biologics and Hope Medicine are speeding up the launch of a first-in-class antibody drug, HMI-115, for endometriosis and androgenic alopecia. The treatment involves a series of subcutaneous injections, has shown promising results in phase 1, and continues to promote hair regrowth even after the treatment is stopped.
A user's progress with hairgrowth using oral minoxidil, oral dutasteride and Nizoral shampoo every once in a while. Replies indicate that the user has seen good results from this treatment, including thickening and darkening of their hair.
The user is experiencing gradual hairgrowth using 5% minoxidil, 0.01% finasteride, vitamins, capixyl serum, niacin, and weekly microneedling, with plans to increase finasteride dosage. Despite some side effects, they remain optimistic about hair transplant results, focusing on the crown and temples.
A user tried various hairgrowth treatments, including drinking topical minoxidil, using oral minoxidil and finasteride, and applying GHK-Cu, growth hormone peptides, and liposomal sulforaphane. They experienced thicker hair, while others discussed the risks and benefits of these methods.
Oral minoxidil can boost hairgrowth but may cause side effects like heart palpitations and increased body hair. Many prefer topical minoxidil due to fewer side effects.
The conversation discusses experiences with NMN supplementation for hairgrowth, with some users reporting increased hairgrowth activity and others seeing no significant changes. OP has been using dutasteride and oral minoxidil, and recently added NMN, noticing increased shedding, which they hope indicates new hairgrowth.
PP405 shows promise in stimulating new terminal hairgrowth by activating dormant follicles, with no systemic adverse effects observed in a short-term trial. However, long-term efficacy remains unproven, and further trials are needed to confirm its potential as a hair loss treatment.
A 24-year-old experienced improved hairgrowth using 5% minoxidil, 1 mg finasteride, and dermastamping, but faced side effects like low libido and mild erectile dysfunction. They plan to reduce finasteride dosage after full results and may consider a hair transplant if thinning recurs.
The user is pleased with their hairgrowth results after using oral minoxidil (2.5mg) for 3 months and finasteride (1mg) for 4 months, despite experiencing significant shedding initially. They prefer oral treatments over topical due to convenience and concerns about toxicity to pets.
Finasteride use resulted in increased hairgrowth but reduced libido for some, leading users to consider topical versions to lessen side effects. Opinions varied on the trade-off between hair benefits and sexual side effects.
Microneedling with minoxidil significantly boosts hairgrowth, even for non-responders to minoxidil alone. The routine includes a 1.5mm dermaroller weekly and minoxidil twice daily, with some users adding finasteride and tretinoin.
The user shared progress pictures showing hairgrowth after 9 months of using 1 mg oral finasteride, 2.5 mg oral minoxidil (recently increased to 5 mg), and 2% ketoconazole shampoo. Users discussed the effectiveness and side effects of these treatments, with some suggesting alternative methods and cautioning about minoxidil dosage.
PP405 is discussed as a potential hairgrowth stimulant, possibly more effective than minoxidil, but not a cure for hair loss. There is skepticism about its ability to regrow "deadzones," and concerns about its impact on those with hair transplants.
The user is experiencing a second hair shedding phase and increased flaking and itching while using minoxidil 5% nightly and microneedling every two weeks, with needle length increasing over time. Other users suggest the hair loss may continue without the use of finasteride.
User shared progress pictures showing hairgrowth from January to March using 1mg finasteride, topical minoxidil with peppermint oil, derma stamping twice a week, and biotin. Commenters are impressed with the quick and significant improvement.
The conversation discusses the effects of Pyrilutamide on hairgrowth after two months, with one person noting that while new hair regrowth isn't apparent, existing hair appears longer and thicker.
A 23-year-old male is seeing hairgrowth after two months using Minoxidil, Finasteride, derma rolling, and supplements like biotin and collagen. Commenters acknowledge the improvement and inquire about side effects and hair shedding.
Chlorine dioxide was discussed as a potential hairgrowth treatment, with a method involving spraying it on the scalp and covering it with a cap. Concerns were raised about its safety, comparing it to bleach.
Androgenetic alopecia is caused by DHT affecting hairgrowth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hairgrowth.
A gel of keratin microspheres promotes hair follicle growth, showing similar effectiveness to minoxidil in mice. The treatment activates hairgrowth pathways and reduces inflammation, with potential applications in drug delivery for hair-related disorders.