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      community IGF-1 and Peptides? Miracle molecule waiting to be found

      in Research/Science  10 upvotes 8 months ago
      The conversation discusses potential hair loss treatments focusing on stimulating IGF-1 at the follicle level using growth-factor cocktails and engineered peptides, such as Acetyl Tetrapeptide-3, Copper Tripeptide-1, Oligopeptide-20, Thymosin-β4, and Palmitoyl Tetrapeptide-7. It suggests that device-assisted delivery methods like microneedling may enhance effectiveness.

      community 3mm microneedling with derma-stamp?

      in Microneedling 8 months ago
      The conversation discusses experimenting with microneedling for hair loss, with OP considering using a 3mm derma-stamp. Other users advise against going beyond 1.5mm to avoid damage.

      community Estenove Transplant Review From NYC Guy Mid 20s

      in Transplants  1 upvotes 10 months ago
      The user had a hair transplant with Estenove, rating the overall experience 6/10 due to logistical issues, unmet expectations, and dissatisfaction with the results. They advise against pricier packages and express regret over the asymmetrical hairline, despite good customer service and post-op care.

      community PP405 Phase 2a press release with early results

      in Research/Science  697 upvotes 10 months ago
      PP405 shows promise in hair regrowth, with 31% of participants experiencing over 20% increase in hair density after 8 weeks. Phase 3 trials are expected in 2026, with potential market availability by 2029-2031.

      community Combining Stemoxydine + Topical Minoxidil

      in Minoxidil  2 upvotes 1 year ago
      Combining stemoxydine with topical minoxidil for hair loss treatment. Users discuss application order and effectiveness, with some skepticism about stemoxydine's benefits.

      community Why isn’t anyone talking about this?

      in Research/Science  29 upvotes 2 years ago
      Hair cloning is being developed by companies like Kangstem Biotech and Stemson, with potential availability in a few years. Initial costs are expected to be high, but prices may decrease over time.

      community Why is Kevin Mann (Haircafe) Hated?

      in Chat  62 upvotes 3 years ago
      Hair loss treatments, including microneedling, minoxidil, finasteride and RU58841; the efficacy of these treatments; criticisms of Kevin Mann's content related to his selective data presentation and biases towards certain treatments; and other topics such as DHT being labeled a "trash hormone" and critiques of other hairloss YouTubers.

      community The likely cost of HMI-115, when it comes out

      in Technology  13 upvotes 3 years ago
      A new potential hair loss treatment called HMI-115, and the cost of this treatment which may be expensive due to production costs but could be competitive with other treatments such as hair transplants.

      community Seriously confused about minoxidil's method of action

      in Minoxidil  6 upvotes 3 years ago
      The conversation discusses confusion about how Minoxidil promotes hair growth compared to other substances like Menthol, which have similar actions. The user mentions personal positive results with peppermint oil extract and is currently trying L-citrulline for its vasodilation effects.

      community Comprehensive Microneedling Guide

      in Microneedling  292 upvotes 3 years ago
      Microneedling for hair restoration involves daily use of a 0.3 mm device and weekly use of a 0.5 mm device. Combining microneedling with Minoxidil can enhance hair growth.

      community Dermarolling is a bit sad innit?

      in Microneedling  232 upvotes 4 years ago
      Hair loss treatments discussed include dermarolling, minoxidil, finasteride, and RU58841. Some users find dermarolling sad, while others mention the complexity of biological systems and limited research funding for hair loss.

      community Quick rant about fin/dut posts on this sub.

      in Finasteride/Dutasteride  175 upvotes 5 years ago
      Hair loss treatments Finasteride and Dutasteride are discussed, with emphasis on their safety and effectiveness. Users share frustration about fear-mongering and side effect discussions, suggesting trust in scientific studies and FDA approval.

      community Does caffeine inhibit 5-α-reductase?

      in Treatment  4 upvotes 6 years ago
      Caffeine may promote hair growth and potentially inhibit 5-α-reductase activity in hair follicles, but its effectiveness and systemic impact remain unclear. Users discuss using topical caffeine solutions, with some experiencing no side effects compared to finasteride.

      community Vitamin D and Thinning

       4 upvotes 6 years ago
      The conversation discusses hair thinning and potential treatments, focusing on vitamin D supplements and their effects. Other suggestions include zinc, a high-protein diet, and coconut oil for hair health.

      community Since there is so much hype for cosmeRNA and HMI-115...

      in Chat  46 upvotes 3 years ago
      Exploring different treatments for hair loss, such as cosmeRNA and HMI-115 which are small interference messenger RNA that inhibits the DHT receptor and an antibody that binds to the prolactin (PRL) receptor respectively; and researching mechanism and environment of hyperresponders.

      community Insane MTF recovery 18 months blocking androgens

      in Progress Pictures  145 upvotes 3 years ago
      Hair loss recovery using estrogen and anti-androgen treatment for 18 months showed significant improvement. However, results vary and alternative treatments like RU58841 and Dutasteride may work without systemic feminization.

      community Physician here AMA – 30M oral Fin 1-1.25 mg daily

      in Update  47 upvotes 3 years ago
      Hair loss treatments, specifically the use of finasteride, microneedling and potentially oral minoxidil. People discussed their experiences with finasteride, its effects on sexual behaviors, as well as potential solutions such as tadalafil or using other growth factor signal peptides for hope in curing male pattern baldness.