Akkermansia bacteria can improve hairgrowth inhibited by testosterone, and metformin may increase Akkermansia, which could help with hair loss related to aging, insulin resistance, and inflammation.
The post discusses the side effects of various drugs causing excess hairgrowth, questioning why only minoxidil is used in the hair loss industry. The conversation includes users sharing their experiences and concerns about potential side effects of these drugs, with some preferring baldness over potential health risks.
The conversation discusses hair loss treatments, specifically Brassica oleracea extract, glucosinolates, and sulforaphane, and their potential to promote hairgrowth. Users also mention minoxidil and finasteride as existing treatments.
Castor oil may help hairgrowth by targeting specific receptors and reducing certain scalp levels, with some users reporting thicker hair. Peppermint oil is suggested as an alternative to minoxidil, while opinions on the effectiveness of plant-based treatments for hair loss vary.
Clascoterone 5% solution shows strong potential for hairgrowth, offering a new treatment for alopecia with minimal side effects. It blocks androgen receptors locally and may be available by late 2026 or early 2027.
Ecklonia cava is suggested as an alternative to finasteride and dutasteride for hairgrowth, potentially offering benefits without their side effects. It is promoted for anti-aging, mood enhancement, and cognitive support.
PP405 is a new hair loss treatment in phase 2 trials that may promote hairgrowth by increasing lactate production and activating hair follicle stem cells. It could potentially replace hormone-disrupting treatments like Minoxidil and finasteride.
Cold shock therapy may promote hairgrowth by stimulating follicular muscles and affecting stem cells. The exact mechanisms and full range of elements involved are not yet fully understood.
NMN shows promise in promoting hairgrowth by reducing oxidative stress and weakening androgens. It may be a beneficial addition to hair loss treatments like Minoxidil and Finasteride.
Stemson Therapeutics announced a breakthrough in hairgrowth technology using stem cells. Users discussed the potential high cost and skepticism about the treatment's accessibility.
A novel hemp extract allegedly promotes better hairgrowth than minoxidil and finasteride, with minimal side effects, but the study's credibility is questioned due to potential bias and confounding factors like peppermint oil. Users express skepticism and suggest sticking with proven treatments like minoxidil and finasteride.
The conversation is about using GHK-CU peptide for hair regrowth. Minoxidil, finasteride, and RU58841 are also mentioned as potential treatments for hair loss.
The conversation discusses hair loss and specific treatments like Minoxidil, Finasteride, and RU58841. It also highlights Procyanidin B-2 as a secret ingredient for hairgrowth.
Increasing IGF-1 may help hairgrowth, but it could also increase hair loss in people with high testosterone. Treatments discussed include l-arginine, glutamine, vanadium, Deer Antler Velvet, ATP, Cocarboxylase, l-carnitine, and Mk677.
Sildenafil (Viagra) shows potential for hairgrowth by enhancing dermal papilla cell proliferation and stimulating perifollicular vessel formation. Users discuss the possibility of using Cialis (tadalafil) similarly, noting its benefits and side effects.
A topical serum made from monounsaturated fatty acids showed rapid hairgrowth in mice within 20 days, but it remains experimental for humans. Users humorously discussed the frequent success of hairgrowth treatments in mice and expressed skepticism about translating these results to humans.
Mallia Aesthetics has developed MAL-838, a hormone-free product derived from sCD83, which stimulates hairgrowth without disrupting the skin microbiome. sCD83 promotes hairgrowth by activating hair follicles and preventing cell death, offering a localized treatment without systemic side effects.
The user is asking if caffeine topicals are effective for hairgrowth, noting they already use Minoxidil and finasteride. They are unsure if caffeine topicals are beneficial or a waste of money.
Topical melatonin was found to significantly increase hair density and decrease scalp conditions like seborrheic dermatitis. The user is considering using it alongside finasteride and oral minoxidil for treating hair loss and scalp health.
Low-dose dutasteride (0.1 mg) is effective for hairgrowth, potentially more so than finasteride, with fewer side effects. East Asians may respond well to these treatments due to hair characteristics.
Oleic acid, microneedling, and emu oil are discussed as potential hairgrowth treatments, with some users expressing skepticism about their effectiveness. Minoxidil and finasteride are recommended as current reliable treatments until more proven solutions are available.
Han Bio plans to start Phase 1 clinical trials for a hairgrowth treatment in 2027 after successful results in mice. Many users express skepticism about the effectiveness of treatments that work on mice but not on humans, and discuss existing treatments like finasteride and minoxidil.
Long aerobic exercise (over 60 minutes) can reduce DHT levels and improve hair health. Some users discuss using Tadalafil (Cialis) to further reduce DHT after exercise, while others mention using treatments like Minoxidil, Finasteride, and RU58841 for hairgrowth.
Oral biotin combined with topical minoxidil may increase hairgrowth rate, though the study was limited to healthy subjects and did not measure hair density. Some users report personal benefits from biotin, such as faster nail growth and healthier hair, but concerns about acne and study quality were also mentioned.
A natural compound called C3A from Aronia Chokeberry can help prevent hair loss by counteracting the effects of DHT. The user has been taking 50 grams of dried organic Aronia Chokeberry daily for 30 days and will update with photos in 60 days.
Rosemary Oil may inhibit the activity of 5α-Reductase, potentially promoting hairgrowth. Specific treatments discussed include Minoxidil, Finasteride, and RU58841.
Creatine may affect hair loss by reducing PGE2 levels, which could influence hairgrowth. The discussion highlights the need for more research on this potential mechanism.