The potential effectiveness of homemade topical spironolactone in treating hair loss, with studies suggesting it is more effective than finasteride and even minoxidil when used as monotherapy. The conversation also mentions that other anti-androgens are being developed which may soon hit the market.
Hair loss treatments, specifically the use of finasteride, microneedling and potentially oral minoxidil. People discussed their experiences with finasteride, its effects on sexual behaviors, as well as potential solutions such as tadalafil or using other growth factor signal peptides for hope in curing male pattern baldness.
The user added melatonin to their 5% minoxidil solution for hairgrowth, using a concentration of 0.0033%, which equates to roughly 2mg for a 60ml bottle. They later reported no significant difference and planned to continue the treatment for a few more months before potentially stopping to observe any changes in shedding.
User xEternex tries hair regrowth with daily broccoli sprouts, apple extract containing procyanidin b2, and microneedling. Others discuss potential issues with the experiment and share their experiences with vegetable consumption and hairgrowth.
The conversation discusses the potential positive effects of melatonin on hairgrowth. The original poster plans to try both oral and topical melatonin and is seeking recommendations for a good source.
The conversation discusses using microneedling and peppermint oil as an alternative treatment for hair loss, with the original poster having previously experienced side effects from finasteride and minoxidil. Another user mentions mixing peppermint oil with jbco (Jamaican black castor oil) for hairgrowth and also experiencing side effects from minoxidil.
Microneedling may enhance hair regrowth by transferring stem cells to dormant follicles, improving the effects of minoxidil. Users discuss using microneedling with needle lengths around 1.5mm to stimulate hairgrowth.
Finasteride works by reducing DHT, which helps stop hair miniaturization. The user is on finasteride and believes it works due to its effect on growth factors and DHT reduction.
Treating hair loss with various remedies, such as Cetirizine and the Big3 complex (minoxidil, finasteride, and RU58841), which have properties like adipogenic, anti-fibrotic and anti-inflammatory. References to research studies are also included.
Stopping Minoxidil caused significant hair loss, which was mostly regained after resuming 1mg Finasteride and 3mg oral Minoxidil. Consistent use of both treatments is essential for maintaining hairgrowth.
Combining therapies like scyllo-inositol, alpha-ketoglutarate, and autophagy-inducing supplements may enhance hairgrowth and prevent hair loss. Reporting individual results can accelerate progress in hair loss treatments.
Follicopeptide (FOL005) by Coegin Pharma will launch as a cosmetic hairgrowth treatment by Q2 2025, showing similar efficacy to finasteride. Users discuss the benefits and skepticism of releasing hair loss treatments as cosmetics rather than drugs.
The effects of finasteride and dutasteride on beard growth, whether minoxidil would help with facial hair loss caused by DHT blockers, and anecdotal evidence from users who have experienced either decreased or increased facial hair density while using these treatments.
PP405 is the most promising future treatment for hair loss, aiming to reactivate dormant hair follicles. Clascoterone 5% is the most promising near-term drug, while current strategies include using finasteride or dutasteride to stabilize hair loss and minoxidil to stimulate growth.
Peptides are being discussed for potential hair loss treatments, but most are not proven effective for this purpose. Minoxidil and finasteride are mentioned as more reliable options for hairgrowth.
A user shared progress on hair regrowth using 5mg oral minoxidil and 0.5mg oral dutasteride daily, noting small hairgrowth and no significant side effects except bushier eyebrows. The conversation includes encouragement, personal experiences with hair loss treatments, and discussions on the effectiveness of microneedling.
The user shared their 5-year progress using finasteride and topical minoxidil for hairgrowth, noting initial success but recent thinning and side effects. They plan to switch to dutasteride and oral minoxidil, addressing low iron levels and monitoring potential side effects.
The user experienced significant hair regrowth using 0.5 mg Dutasteride and 5 mg Minoxidil daily for almost 8 months, with noticeable improvements despite initial shedding. They reported no side effects other than hairgrowth and plan to continue the treatment.
A user shared their 5-month hair loss treatment progress using oral finasteride, Regaine foam, 2DDR serum, and microneedling, noting improvements in hairgrowth at the crown and front. They are considering increasing microneedling frequency or adding a shampoo to their routine.
Moringa extract and oil are suggested to help with hair loss, with some users combining it with treatments like minoxidil, finasteride, and dutasteride. Moringa is claimed to improve hairgrowth and health, but evidence is mostly anecdotal.
The conversation discusses using minoxidil with microneedling and considering tretinoin to enhance hairgrowth, especially for those who are weak responders to minoxidil. It also explores the potential of using tazarotene, a stronger retinoid, to boost minoxidil's effectiveness and addresses purchasing tretinoin from Germany.
Cyperus rotundus oil is suggested as a natural treatment for androgenic alopecia, potentially inhibiting hairgrowth without affecting testosterone levels. The conversation questions its effectiveness and safety for scalp use.
The regimen for hair loss includes topical finasteride, clascoterone, tretinoin, minoxidil, oral saw palmetto, beta-sitosterol, vitamin D, microneedling, and anti-fungal shampoo. Expected benefits are increased hairgrowth and density, with considerations for potential skin irritation and interactions between treatments.
User had a hair transplant and used a finasteride and minoxidil spray for 6 months with no results. After adding finasteride tablets for 1 month, they saw significant hairgrowth improvement.
A user shared their experience with hair loss treatments, noting improvement after switching from minoxidil and finasteride to dutasteride. They observed new hairgrowth and reduced scalp inflammation, expressing hope for further progress.
The conversation discusses microneedling for hair loss, with one user trying 0.3mm daily without feeling pain and questioning its effectiveness. Another user suggests that 0.3mm is too shallow and recommends 0.5mm twice a week or 0.75mm once a week for hairgrowth.
Capronium Chloride and Trichoxidil are suggested as better alternatives to Minoxidil for hairgrowth without heart side effects. The Japanese Dermatological Association recommends topical Minoxidil over Capronium Chloride.
A user shared a 6-month hair loss treatment routine including Mexican finasteride (1.25mg every other day), daily minoxidil, bi-weekly dermarolling, and ketoconazole shampoo twice a week, noting significant crown growth and some frontal hairline improvement with initial side effects that have since subsided. They are seeking advice to improve results, particularly at the frontal hairline, without resorting to a hair transplant.
A user shared a 3-month hair regrowth transformation using Finasteride 1mg, Minoxidil, and occasional derma rolling. Some responders are skeptical of the rapid growth, while others suggest the user might be an exceptional responder to the treatment.