The user has been experiencing hair loss for over 5 years and is currently using a topical treatment of finasteride, minoxidil, and tretinoin, along with derma rolling and a hairgrowth oil. They have previously tried oral finasteride, pyrithione zinc, RU58841, and dutasteride, but are seeking advice on whether to retry dutasteride or find a more reliable source for RU58841 due to ongoing hair density loss.
The user "macroburstmedia" is asking if adding topical minoxidil to their current treatment of oral minoxidil and finasteride can improve hairgrowth. Some users have shared their experiences with using both oral and topical minoxidil, while others suggest increasing the oral minoxidil dose instead.
The effectiveness of microneedling as a hair loss treatment, with evidence from studies and anecdotal accounts from other users. It is suggested that combining microneedling with minoxidil or finasteride may be more effective than using microneedling alone, although some people have had success using only microneedling.
The conversation discusses making a topical melatonin solution for hair loss treatment, questioning if isopropyl alcohol can dissolve melatonin. Melatonin is soluble in lipids and alcohol, but it's unstable and should be mixed fresh regularly; it may help hairgrowth by affecting certain cellular signaling pathways and has anti-androgenic effects.
Procyanidin B2, a compound derived from Annurca apples, as a potential treatment for pattern hair loss. Several clinical studies were mentioned, which found that procyanidin B2 could increase hairgrowth, density, and keratin content. Other treatments such as Minoxidil, Finasteride, and RU58841 were not discussed.
Oral minoxidil and finasteride can lead to quick hairgrowth, with some users noticing changes in as little as 2-3 weeks, though head hair may take longer. Many prefer oral minoxidil over topical due to convenience, and some also use ketoconazole shampoo and other topical treatments.
A 28-year-old male experienced significant hair regrowth using dutasteride 0.5 mg and 2.5 mg oral minoxidil after previous treatments with minoxidil and finasteride became less effective. He reported no major side effects, except for unwanted hairgrowth in certain areas.
Minoxidil and finasteride work through different mechanisms; minoxidil-dependent hair requires continued use to maintain growth, while finasteride prevents further hair loss but cannot sustain minoxidil gains alone. Current treatments like minoxidil, finasteride, and others need indefinite use, as no permanent solution exists yet.
Methods of treating hair loss, such as using Minoxidil and Finasteride, as well as the potential use of RU58841. People have shared their experiences with these treatments, discussing the success of them in aiding hairgrowth.
The effects of finasteride and dutasteride on beard growth, whether minoxidil would help with facial hair loss caused by DHT blockers, and anecdotal evidence from users who have experienced either decreased or increased facial hair density while using these treatments.
A 30-year-old man with diffuse hair thinning shared his hair regrowth regimen, which includes increasing Vitamin D intake, taking oral castor oil, using a dermapen, and various supplements like Glycine, K2, Vitamin E, Vitamin C, Aspirin, Sodium Bicarbonate, and a multivitamin. He also mentioned inconsistent use of Minoxidil, Peppermint Oil, Zix, and topical Castor Oil, and negative side effects from Finasteride, RU58841, and Nizoral.
A 17-year-old is concerned about hair loss and is considering treatments like Minoxidil, finasteride, and RU58841. They feel uncertain about whether to start treatment.
A 27-year-old at Norwood 3 is starting a hair loss treatment journey using finasteride, dutasteride, minoxidil, biotin, scalp massages, and ketoconazole shampoo. The focus is on reducing DHT and stimulating growth, with finasteride emphasized as the key long-term solution.
The post discusses frustration over the limited and not always effective treatments for hair loss, mainly Minoxidil and Finasteride. The conversation includes mentions of potential new treatments like GT20029, HMI-115, CosmeRNA, KX-826, and microneedling, but also highlights the challenges of funding and prioritizing research in this area.
A user has been experiencing hair loss for 4 years, with treatments like minoxidil, finasteride, and various supplements proving ineffective. They were diagnosed with fibrosing alopecia in a pattern distribution, a condition that may require a combination of anti-inflammatory and hairgrowthtreatments.
A user shared progress on hair regrowth using 5mg oral minoxidil and 0.5mg oral dutasteride daily, noting small hairgrowth and no significant side effects except bushier eyebrows. The conversation includes encouragement, personal experiences with hair loss treatments, and discussions on the effectiveness of microneedling.
There is no imminent cure for hair loss, but treatments like Minoxidil, Finasteride, and new drugs such as KX-826, GT-20029, and PP405 are being explored. Current solutions focus on slowing hair loss and stimulating growth, with hopes for better options in the future.
The conversation discusses the synthesis and potential use of JXL069 and PP405 for hair loss treatment, with skepticism about their effectiveness and concerns about safety. Users mention that JXL069 has shown no results in hairgrowth, and there is confusion about its identity and effectiveness compared to PP405.
The user has been using minoxidil, finasteride, dermastamping, and Nizoral for hair loss with initial success but is considering adding PRP due to slowed progress. Concerns about PRP include potential ineffectiveness and whether it could harm existing hairgrowth or interfere with current treatments.
Pelage Pharmaceuticals is developing PP405, a topical treatment for hairgrowth, currently in Phase 2a trials. There is skepticism about the company's claims, and no fast-tracking approval timeline has been detailed.
The conversation is about finding a high-quality copper peptide powder for long-term hairgrowth, to be mixed with rosemary oil. It also suggests using finasteride for hair loss treatment.
After almost 9 months of taking 1mg Finasteride, the user started seeing good results with increased scalp coverage and new hairgrowth around the hairline. They advise others to be patient and stick with the treatment for about a year despite initial shedding and slow progress.
The user started using 5% topical Minoxidil in early November and noticed some hairgrowth, especially on the crown, and has just begun taking 1mg oral Finasteride. They plan to continue treatment and share progress updates.
A user discusses using latanoprost, a costly treatment that may extend the hairgrowth phase and improve hair quality, wondering why it's not more popular. They already use a combination of finasteride and minoxidil and plan to incorporate latanoprost into their routine.
SCUBE3, a protein linked to hairgrowth in moles, was discovered over 25 years ago and is being developed by Amplifica for potential hair loss treatment. Concerns exist about SCUBE3's association with cancer, as it is a protein that promotes cell growth, which could potentially trigger cancer development if used for hairgrowth therapy.
A user shared their hair regrowth progress after using oral minoxidil (3mg) and finasteride (1.1mg) for 11 weeks, noticing significant improvement and no bald spots, with the side effect of increased eyebrow and eyelash growth. They plan to update again in 6-9 months and have inspired friends to try the same treatment.
The user showed a one-year hair regrowth progress using finasteride only, after stopping minoxidil due to its toxicity to cats. They noticed hairgrowth around six or seven months into treatment.
A user shared their hair regrowth progress, attributing success to a consistent routine using finasteride, hairgrowth oil, Hims shampoo, a derma roller, and 5000 mcg biotin pills. They emphasized the importance of representation for people with similar hair types and encouraged others to stick with their treatment plans.