Collagen peptides are recommended for hair and skin benefits, with users noting improvements in hair and skin health. However, evidence on their effectiveness for hairgrowth is inconclusive.
Rob English, known for promoting scalp massages for hair regrowth, now sells his own brand of finasteride and minoxidil. Opinions are mixed, with some calling him a charlatan and others acknowledging his shift towards scientifically-backed treatments.
Pelage Pharmaceuticals' PP405 aims to treat hair loss by reactivating dormant hair follicle stem cells, showing promising results in early trials. The company plans to present their findings at the American Academy of Dermatology Annual Meeting in 2026.
KX-826 (Pyrilutamide) 0.5% and 1.0% solutions showed promising results in increasing hair count for male androgenetic alopecia, with the 0.5% dose slightly outperforming the 1% dose. The treatment was well-tolerated with no sexual side effects, but skepticism remains due to past inconsistencies in trial results.
Piroctone Olamine at 1% is recommended for reducing scalp inflammation and encouraging hairgrowth. The user seeks recommendations for UK shampoos/conditioners containing this ingredient.
Switching from finasteride to dutasteride led to hair density loss, prompting consideration of returning to finasteride. Consistency with dutasteride and adding RU58841 did not prevent the loss, and users suggest giving dutasteride more time or consulting a dermatologist.
A South Korean company, Therazyne, has developed a promisinghair loss treatment using a WNT chain surrogate that binds to Frizzled 7, with human follicle testing expected soon. Current treatments like minoxidil and finasteride are not seen as cures, and while optimism exists for future solutions like PP405, approval processes are lengthy.
The conversation discusses skepticism about a user's hair restoration progress, with accusations of the post being fake and promoting an AI app. Treatments mentioned include dutasteride and oral minoxidil, with some users discussing side effects and safety of minoxidil.
Hmi115, a prolactin receptor blocker, showed promise for hairgrowth, but results from Phase 2 trials have not been published. ABS-201, an AI-based analog, is expected to begin trials in December 2025, while commercialization of treatments like PP-405 is anticipated around 2027.
A naturally occurring sugar, 2-deoxy-D-ribose, may promote hairgrowth by forming new blood vessels. There is skepticism about its effectiveness and concerns about potential side effects, with some users comparing it to existing treatments like Minoxidil and finasteride.
Pelage Pharmaceutical raised $120 million to continue research on PP405, a promisinghair loss treatment that showed a 20% increase in hair density in 31% of men during a Phase 2a trial. The treatment was well-tolerated, with no systemic absorption, and Phase 3 trials are planned for 2026.
Nizoral shampoo effectively reduces scalp itchiness and dandruff, particularly for those using minoxidil, and may promote hairgrowth despite not being FDA-approved for this purpose. Users report significant improvements in scalp health and reduced itchiness with regular use.
The user "Top_Replacement_7777" shared their positive results with finasteride for hair loss. They asked about maintaining their hair with finasteride and the impact of vaping on hairgrowth. Another user reassured them that vaping wouldn't affect their progress.
A user is interested in Absci's AI-driven antibody platform, ABS-201, for treating androgenetic alopecia, which shows promising preclinical results and potential for hair regrowth and pigmentation restoration. However, concerns are raised about the drug's development timeline and its advantages compared to existing treatments.
Vitamins and minerals like vitamin E, zinc, and iron may aid hairgrowth, especially in cases of deficiency. Pumpkin seed oil, saw palmetto, horsetail, and AminoMar show some promise for improving hair health and count.
Treating androgenic alopecia with minoxidil, finasteride, and antiandrogens, alongside exercise, cryotherapy, and natural substances to stimulate cold receptors for better hairgrowth. The method focuses on enhancing treatment effectiveness by considering environmental and behavioral factors and the role of cold receptors and muscle stress.
RT1640, a combination of cyclosporin A, minoxidil, and RT175, is discussed as a potential treatment for hair regrowth and repigmentation. The unique formulation aims to enhance hair follicle growth and restore hair pigment without the negative side effects of immunosuppressants.
Hair loss treatments discussed include minoxidil, finasteride, and RU58841. Salon products and supplements generally don't work for hair regrowth unless there's a severe nutritional deficiency, while hormonal treatments like estrogen and spironolactone can be effective.
The conversation discusses the use of autologous exosomes for hair loss, questioning their effectiveness and seeking real user experiences. The user is skeptical about the treatment's legitimacy and is looking for honest feedback on its results.
The conversation is about a hair loss treatment plan involving finasteride, minoxidil, microneedling, GHK-CU injections, Nizoral shampoo, and RU58841. The user is advised to start with a simpler regimen to minimize side effects and assess effectiveness before adding more treatments.
Tretinoin's effectiveness for hair regrowth alone is questioned, with interest in its use with oral minoxidil. The discussion also considers whether finasteride or dutasteride is the better DHT blocker and if switching to dutasteride is advisable for those without side effects from finasteride.
Using ketoconazole shampoo can cause hair dryness, especially when combined with Minoxidil. Users suggest using conditioner, adding oils like rosemary and peppermint, or reducing shampoo frequency to mitigate dryness.
A user shared their positive experience with a hair transplant at Diamond Hair Clinic in Istanbul, performed by Dr. Mehmet Demircioglu, using the Sapphire FUE technique with 4500 grafts. They previously used minoxidil and finasteride, which helped slightly, and plan a follow-up surgery for further improvements.
A new hair loss treatment involving Keratin Microsphere Gel is discussed, with skepticism and jokes about its effectiveness and comparisons to other treatments. Users are doubtful and make light of the situation, referencing past disappointments and the study's focus on mice.
Hair loss treatments discussed include Minoxidil, Finasteride, and Spironolactone. One user shares success with Finasteride, Minoxidil, and low-dose Cyproterone Acetate, but warns against long-term use of oral anti-androgens.
Prostaglandin balance affects hair loss, particularly in conditions like Lichen Planopilaris, where an imbalance can lead to hair follicle damage. Treatments mentioned include prostaglandin analogs and Pioglitazone HCL, with a focus on maintaining prostaglandin equilibrium for potential hair regrowth.
The user is seeking advice on hair loss treatments, considering options like finasteride, dutasteride, minoxidil, or a hair transplant. They are concerned about how their mixed hair color might affect a transplant.
Fish oil may not significantly improve hair health, but it is beneficial for overall health, especially for those who don't consume fish. Some users report better skin and less frizzy hair with omega-3 supplements, but no clear evidence of hair improvement.
A 27-year-old actor shared his positive experience with two hair transplant surgeries, highlighting the importance of customization and detail for a natural look. He is taking finasteride to prevent future hair loss.
PP405 and hair cloning are discussed as potential treatments for reversing hair loss from Norwood 7 to Norwood 1. Hair cloning is seen as a more permanent solution, while PP405's effectiveness and long-term effects remain uncertain.