Astaxanthin may cause increased hair shedding, affecting even transplanted hair and eyebrows. The user has tried various treatments for androgenicalopecia, including minoxidil, finasteride, and RU58841.
GT20029 is a topical treatment that degrades androgen receptors to prevent hair thinning and loss, potentially offering fewer side effects than systemic treatments like finasteride. Concerns include its impact on hair texture and potential systemic effects, with market availability speculated in 3 to 5 years.
The conversation discusses topical androgen receptor blockers for hairloss, mentioning Clascoterone, Pyrilutamide, GT20029, and RU58841. Ketoconazole's effectiveness and application methods are also debated.
RU58841 is discussed as a topical anti-androgen for hairloss, but its effectiveness and safety are not well-documented, leading to mixed opinions and experiences among users. Some combine it with finasteride, but concerns about side effects and lack of FDA approval limit its popularity.
A hair journey of someone who started using Minoxidil, Finasteride and Dutasteride to treat their AndrogenicAlopecia. The user reported successful results with the medication, including compliments from strangers.
The conversation discusses whether creatine causes hairloss for those using finasteride or dutasteride, with some suggesting creatine might increase DHT or upregulate androgen receptors, potentially leading to hairloss. Others argue the evidence is not conclusive, citing limited studies and personal anecdotes, with some avoiding creatine as a precaution.
A Danish citizen warns against NordicHairGrowth.com, claiming it falsely advertises products for treating androgenicalopecia. The company's ingredients and claims are disputed, including a non-existent patented ingredient RP-24, and a non-verifiable clinical trial.
Lichen Planopilaris (LPP), a form of permanent hairloss, which can be mistaken for seborrheic dermatitis and is characterized by scalp itching, burning, redness, and dandruff. Treatment options discussed include steroidal creams, finasteride, minoxidil, and RU58841.
NMN shows promise in promoting hair growth by reducing oxidative stress and weakening androgens. It may be a beneficial addition to hairloss treatments like Minoxidil and Finasteride.
In this conversation, 4990 discussed various treatments for hairloss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.
Dutasteride may inhibit androgen receptors in addition to reducing DHT, potentially explaining its effectiveness over finasteride for hairloss. Concerns about its impact on muscle growth are debated, with some suggesting no significant effects.
Oral minoxidil is considered a safe and effective treatment for hairloss at low dosages, with minimal cardiac risks. Users report positive results, though some experience side effects like increased heart rate and skin changes, and consulting a doctor is advised.
A user's hair regrowth journey using biotin and minoxidil after initial treatments with Nizoral shampoo and Ketoconazole serum didn't work. The comments suggest the hairloss might not be male pattern baldness (MPB), but possibly Alopecia Areata, an autoimmune disorder, and recommend getting a second opinion and considering other treatments like corticosteroids.
Combining therapies like scyllo-inositol, alpha-ketoglutarate, and autophagy-inducing supplements may enhance hair growth and prevent hairloss. Reporting individual results can accelerate progress in hairloss treatments.
Clascoterone 5% solution shows strong potential for hair growth, offering a new treatment for alopecia with minimal side effects. It blocks androgen receptors locally and may be available by late 2026 or early 2027.
Minoxidil helped with hairline regrowth, but stopping it led to hairloss, suggesting circulation issues. Dermarolling, collagen peptides, and oils like castor and rosemary are recommended for improving hair health.
A user shared their positive experience with a hair transplant of 3500 grafts, showing significant improvement in appearance after 5 months. They underwent the procedure at Heva Clinic in Istanbul for $2,300 USD, which included aftercare, and attributed their hairloss to both genetics and traction alopecia from tight hairstyles.
The user has been using oral dutasteride and minoxidil for over a year without regrowth or stability, and hairloss continues. Suggestions include checking for inflammation, considering a scalp biopsy, and trying microneedling, topical anti-androgens, or a hair transplant.
Excess sebum rich in cholesterol and triglycerides can lead to hairloss through inflammation, with treatments like Ciclopirox shampoo, Benzoyl Peroxide shampoo, and Clindamycin gel recommended for managing conditions like seborrheic dermatitis and folliculitis. Pioglitazone is suggested for Lichen Planopilaris, while Omega-3s and reducing processed foods may improve sebum quality, though genetic factors play a significant role.
Evidence-based treatments for androgenicalopecia, such as minoxidil, finasteride, low-level laser light therapy, dutasteride, platelet-rich plasma, and topical ketoconazole. It discusses the efficacy, safety, and mechanism of action of these treatments, as well as future developments in understanding this polygenic condition.
Dutasteride can slow hairloss and potentially stabilize it, but results vary by individual. Minoxidil and dutasteride may lose effectiveness over time, and hairloss might continue despite treatment.
Hairloss may be linked to the TRPS1 gene and protein, not just DHT. Amplifica's AMP-303 targets mesenchymal stem cells and shows promise in treating hairloss, unlike Pelage's PP405.
A woman with androgeneticalopecia uses Dutasteride and Bicalutamide but feels devastated due to increased sensitivity to DHT. She considers wigs, Minoxidil, and seeks advice on options like spironolactone, hair transplants, and therapy.
The user is experiencing diffuse androgenicalopecia and is trying various treatments, including 5mg finasteride, loniten, and Formula 82D, which contains dutasteride, a steroid, and tretinoin. They report potential regrowth with Formula 82D, despite previous treatments being ineffective.
A new hairloss treatment involving Keratin Microsphere Gel is discussed, with skepticism and jokes about its effectiveness and comparisons to other treatments. Users are doubtful and make light of the situation, referencing past disappointments and the study's focus on mice.
The conclusion of the conversation is that the user should consider using treatments such as finasteride, minoxidil, and RU58841 to potentially reverse their hairloss. Other suggestions include using hairloss concealers and maintaining a healthy diet.
Hairloss is often misunderstood by those not affected, leading to frustration for those who research treatments like Minoxidil, finasteride, and hair transplants. Many people offer well-meaning but uninformed advice, while those knowledgeable about hairloss focus on proven treatments.
Hairloss involves more than just DHT, with genetic factors like TRPS affecting hair follicles. Treatments such as Amplifica's AMP-601 and AMP-303 target stem cells for potential hair growth solutions.
Hairloss treatments include topical and oral minoxidil, low-level laser light therapy, and peptide serums. Bryan Johnson avoids finasteride and dutasteride due to potential side effects, focusing instead on his own protocol with these treatments.
Hairloss after telogen effluvium (TE) with thinning and possible scarring, treated with 5 mg oral minoxidil. Concerns about scarring alopecia and lack of regrowth, with suggestions to consider finasteride for better results.