Users discuss using pyrilutamide for hairloss, seeking alternatives to 5AR inhibitors. They mention using minoxidil, ketoconazole shampoo, and RU58841.
The conversation discusses preferences for hairloss treatments, specifically finasteride over dutasteride. Users share personal experiences, cost considerations, FDA approval status, and potential side effects, with some switching between treatments to find what works best for them.
Finasteride is believed to slow down hairloss significantly, but may not completely stop it for everyone. Effectiveness and duration vary by individual, with some users experiencing positive results for over 10 years, while others see less benefit.
Stopping creatine led to reduced hairloss for some, despite no proven link between creatine and hairloss. Users shared experiences, with some using minoxidil and finasteride to manage hairloss.
The conversation compares Finasteride and Dutasteride for hairloss treatment, discussing their effectiveness and side effects. Users share personal results and consider combining treatments like Dutasteride with RU58841.
The conversation discusses DIY cosmetic procedures like PRP, mesotherapy, and micro-needling, with some users experimenting with Minoxidil, finasteride, and RU58841 for hairloss. It highlights a community of mostly older women performing these treatments themselves.
The conversation is about the lack of improvement in hairloss after using Pyrilutamide for 14 weeks, with the original poster unable to use Finasteride due to depression. Replies suggest that Pyrilutamide, like RU58841, may not work for everyone, and a more potent drug is being developed by Kintor.
Understanding that the importance of hairloss should not be overstated and encouraging self-love and confidence regardless of physical appearance. People discussed how they were feeling about their own hairloss and shared tips on treatments like Minoxidil, Finasteride and RU58841.
A user's experience with the hairloss treatment Pyrilutamide KX-826, which has resulted in some side effects and shedding. The conversation also includes advice for baseline pictures and trying treatments for at least 6 months.
A potential new treatment for hairloss, Pyrilutamide, and the discussion of whether or not people should still be taking traditional treatments like Minoxidil and Finasteride with it.
Kintor's Pyrilutamide results for hairloss treatment will be released soon. The treatment may replace current treatments like finasteride and minoxidil without systemic side effects.
The conversation discusses the lack of significant advancements in hairloss treatments since the introduction of finasteride 22 years ago, with many expressing frustration over the failure of new projects and skepticism about future developments. Some users mention hair transplants and other potential alternatives like Alfatradiol and Fluridil, but acknowledge finasteride's dominance in the market due to its effectiveness and affordability.
A user who was able to regrow hairloss with 1mg of finasteride daily over 3 years, the effectiveness of finasteride for different races, and potential side effects associated with taking finasteride.
PP405 is the most promising future treatment for hairloss, aiming to reactivate dormant hair follicles. Clascoterone 5% is the most promising near-term drug, while current strategies include using finasteride or dutasteride to stabilize hairloss and minoxidil to stimulate growth.
A 35-year-old man with 10 years of hairloss at NRW7 started using topical Minoxidil and noticed some hair regrowth. He plans to continue with Minoxidil, add microneedling, and possibly try topical treatments like finasteride or dutasteride.
The user shares a positive experience with Dutasteride for hairloss, noting increased hair density and minimal side effects after switching from Finasteride. They prefer oral Dutasteride and avoid Minoxidil due to its inconvenience and potential risks.
Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hairloss by blocking DHT and promoting hair growth.
The conversation discusses using estradiol and its derivatives for hairloss without causing feminization. Users mention alternatives like alfatradiol, topical 17b-Estradiol, and DIM (Diindolylmethane).
RU58841, a potential hairloss treatment, was not commercialized due to marketability issues and lack of long-term safety data. Concerns about its formulation and delivery methods further complicate its use.
A user shared their positive experience with finasteride and minoxidil for hairloss, noting significant improvement and regrowth after 1.5 years of treatment, despite initial side effects. They are now happy with their hair and personal life.
The conversation discusses the role of NADPH in hairloss and the potential impact of creatine and B complex vitamins on hair shedding. The user theorizes that increasing NAD levels with B complex vitamins may reduce hair shedding, despite using finasteride and minoxidil for 9 months.
The user "Zealousideal-Pack340" shared their 5-month results on a natural hairloss treatment protocol, which included massages, vitamins, green tea, and pumpkin seeds. Some users suggested using medications like finasteride and minoxidil for better results, while others criticized the effectiveness of natural remedies. Overall, there was no clear consensus on the progress of the user's hair regrowth.
The conversation is about using a 1mm derma roller for hairloss treatment, including cleaning the scalp with isopropyl alcohol and using castor oil mixed with coconut or olive oil afterward. The user seeks advice on the routine and mentions expected gains.
The post discusses using Sandalore as a potential hairloss treatment, emphasizing precise measurements and safe handling. The user compares Sandalore's effects to Minoxidil and mentions preparing a solution with ethanol and DMSO.
Finasteride and minoxidil are recommended as first-line treatments for hairloss, with dutasteride and oral minoxidil as stronger options if needed. Hair transplants should only be considered after achieving stability with medication, and non-surgical options are suggested if medications are ineffective.
Dutasteride is seen as more effective than finasteride for hairloss but may have more side effects and a longer half-life. Some start with finasteride for fewer side effects, while others switch to dutasteride for better results.
The conversation discusses the potential impact of creatine on hairloss, with some users sharing personal experiences of increased shedding while others argue there's no scientific evidence linking creatine to hairloss. The original poster switched from finasteride to dutasteride and is considering resuming creatine after monitoring its effects on hairloss.
RU58841 is a strong non-steroidal antiandrogen for hairloss but may cause cardiovascular issues in some users. Alternatives like Pyrilutamide and Breezula are suggested due to better safety profiles and lower systemic risks.
A 22-year-old is using 1mg finasteride daily for hairloss, noting some scalp thickening but still experiencing visible thinning. They are considering oral minoxidil due to concerns about topical application with cats at home, and others in the conversation share positive experiences with oral minoxidil, reporting no side effects and significant hair regrowth.