Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hairloss by blocking DHT and promoting hair growth.
The conversation discusses using estradiol and its derivatives for hairloss without causing feminization. Users mention alternatives like alfatradiol, topical 17b-Estradiol, and DIM (Diindolylmethane).
RU58841, a potential hairloss treatment, was not commercialized due to marketability issues and lack of long-term safety data. Concerns about its formulation and delivery methods further complicate its use.
A user shared their positive experience with finasteride and minoxidil for hairloss, noting significant improvement and regrowth after 1.5 years of treatment, despite initial side effects. They are now happy with their hair and personal life.
The conversation discusses the role of NADPH in hairloss and the potential impact of creatine and B complex vitamins on hair shedding. The user theorizes that increasing NAD levels with B complex vitamins may reduce hair shedding, despite using finasteride and minoxidil for 9 months.
The user "Zealousideal-Pack340" shared their 5-month results on a natural hairloss treatment protocol, which included massages, vitamins, green tea, and pumpkin seeds. Some users suggested using medications like finasteride and minoxidil for better results, while others criticized the effectiveness of natural remedies. Overall, there was no clear consensus on the progress of the user's hair regrowth.
The conversation is about using a 1mm derma roller for hairloss treatment, including cleaning the scalp with isopropyl alcohol and using castor oil mixed with coconut or olive oil afterward. The user seeks advice on the routine and mentions expected gains.
The post discusses using Sandalore as a potential hairloss treatment, emphasizing precise measurements and safe handling. The user compares Sandalore's effects to Minoxidil and mentions preparing a solution with ethanol and DMSO.
Finasteride and minoxidil are recommended as first-line treatments for hairloss, with dutasteride and oral minoxidil as stronger options if needed. Hair transplants should only be considered after achieving stability with medication, and non-surgical options are suggested if medications are ineffective.
Dutasteride is seen as more effective than finasteride for hairloss but may have more side effects and a longer half-life. Some start with finasteride for fewer side effects, while others switch to dutasteride for better results.
The conversation discusses the potential impact of creatine on hairloss, with some users sharing personal experiences of increased shedding while others argue there's no scientific evidence linking creatine to hairloss. The original poster switched from finasteride to dutasteride and is considering resuming creatine after monitoring its effects on hairloss.
RU58841 is a strong non-steroidal antiandrogen for hairloss but may cause cardiovascular issues in some users. Alternatives like Pyrilutamide and Breezula are suggested due to better safety profiles and lower systemic risks.
A 22-year-old is using 1mg finasteride daily for hairloss, noting some scalp thickening but still experiencing visible thinning. They are considering oral minoxidil due to concerns about topical application with cats at home, and others in the conversation share positive experiences with oral minoxidil, reporting no side effects and significant hair regrowth.
Some individuals do not respond to oral minoxidil for hairloss, despite it generally working by improving blood flow to hair follicles. Factors like metabolism, drug interactions, and individual variations in the drug's activation may influence its effectiveness.
The post is about a user's progress pictures of their hairloss over a span of 4.5 years. They did not use finasteride or minoxidil for their hairloss treatment.
Scalp tension from the occipitalis muscle is theorized to contribute to hairloss, but most believe DHT and genetics are the main causes. Treatments like finasteride and minoxidil are considered more effective than addressing scalp tension.
PP405, a potential hairloss treatment, is facing delays in releasing Phase 2 results, causing frustration among users who compare it to past failed treatments. Despite skepticism, some remain hopeful about PP405's future, while others discuss alternative treatments like Clascoterone and its expected market release.
Finasteride and minoxidil significantly improved a user's hairloss, starting at age 17, leading to a full head of hair by age 19 without side effects. The user prefers oral minoxidil over topical due to better results and less hassle.
Finasteride is generally seen as more successful for hairloss than Dutasteride, with fewer negative experiences reported. Dutasteride is considered more effective but often leads to more complaints, possibly due to higher expectations or improper use.
Finasteride, dutasteride, and minoxidil are discussed as effective hairloss treatments, with mixed opinions on their use and side effects. The conversation highlights a divide between supporting medical treatments and accepting baldness.
UCLA's PP405 shows promise in reactivating dormant hair follicles for hairloss treatment but is still in clinical trials. Minoxidil and finasteride remain common treatments until PP405 becomes available.
The conversation discusses the effectiveness and safety of hairloss treatments, specifically RU58841 and Pyrilutimide (Pyril), with users sharing that Pyril was no more effective than a placebo and expressing concerns about the safety of RU58841 based on personal experiences and the lack of pharmaceutical interest.
A user is organizing a group buy for various compounds aimed at reversing hairloss and gray hair, and improving brain health and fat loss. The user has developed a treatment plan based on extensive research and is inviting others to participate, with the option to choose only the compounds they need.
A user's experience with taking dutasteride and minoxidil for hairloss, with other users providing advice to continue treatment for at least 12 months and including dermarolling as well as dietary changes.
A user who has tried multiple treatments for hairloss, including oral and topical finasteride and liposomal finasteride, but experienced severe side effects in each case; the user is considering trying RU58841 or aromatise inhibitors as alternatives.
People discussing their experiences with natural treatments for hairloss, such as essential oils, deep scalp massages, anti-inflammatory measures, and supplements. Most of the replies suggest that these treatments are not effective and recommend medication such as minoxidil or finasteride instead.
The conversation discusses using retinol to enhance minoxidil's effectiveness for hairloss, with a user considering The Ordinary's 0.5% retinol and seeking advice on azelaic acid concentration. Other users suggest using tretinoin instead and consider pre-formulated products combining minoxidil, tretinoin, and azelaic acid, but the original poster has not seen improvement from dermarolling.
An 18-year-old has been using minoxidil and finasteride for hairloss since age 15, recently adding dutasteride and GHK-Cu, but sees no significant improvement and is considering a hair transplant. Concerns are raised about using hormone suppressors at a young age, with suggestions to explore other treatments like dermarolling, diet changes, and checking for deficiencies.
The conversation discusses the use of dutasteride and minoxidil for hairloss treatment, with concerns about potential side effects and the effectiveness of dutasteride compared to finasteride. The user is advised to monitor for side effects and consult with a doctor, while also considering the differences between the medications.