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Pelage is moving to Phase III clinical trials for PP405, a hair loss treatment, with results to be presented at a medical meeting. Users express skepticism and hope, comparing it to existing treatments like Minoxidil and finasteride, while discussing the potential for new hair growth in previously bald areas.

A 31-year-old Australian had a successful hair transplant in Turkey for $10,000 AUD, using minoxidil and finasteride to combat hair loss. He now has a full head of hair, increased confidence, and continues using finasteride with occasional minoxidil.

Pelage received $120 million for phase 3 of PP405, a potential hair loss treatment, but there is skepticism about its success. Some users believe any improvement over finasteride is a win, while others expect full hair regrowth.

The conversation discusses the potential for developing a biologic "DHT sponge" to neutralize DHT in the bloodstream as a treatment for hair loss, suggesting it could be more targeted and have fewer side effects than current treatments like finasteride and dutasteride. Concerns include the complexity, cost, and potential side effects of such a treatment, as well as skepticism about its feasibility and market interest.

A user shared progress pictures after one year of using 2.5mg Minoxidil and 1.25mg Finasteride for hair loss. The discussion includes suggestions for additional treatments like dermastamping, dutasteride, and increasing Minoxidil dosage, with mixed opinions on the effectiveness of current treatments.

A 21-year-old shared a 7-month update on using 1mg finasteride and minoxidil for hair loss, reporting positive results with no side effects except watery semen. The user initially stopped minoxidil due to inconvenience but resumed it after shedding, and is satisfied with the progress despite some thinning at the crown.

Follicopeptide (FOL005) by Coegin Pharma will launch as a cosmetic hair growth treatment by Q2 2025, showing similar efficacy to finasteride. Users discuss the benefits and skepticism of releasing hair loss treatments as cosmetics rather than drugs.

A user asked if applying oil (olive, coconut, etc.) to the scalp for dryness and hair loss is effective, as recommended by a dermatologist. They expressed doubt about the advice and sought opinions on its usefulness.

A user shared a 60-day progress update on hair regrowth using only 5% Minoxidil foam once daily. Others suggested adding finasteride to address the underlying cause of hair loss and maintain long-term results.

A 30-year-old uses Dutasteride, Minoxidil, biotin, dermarolling, Anaphase+ shampoo, and Nizoral for hair loss. Some commenters question the need for such extensive treatment given the minimal hair loss.

The conversation is about using natural DHT blockers like pumpkin seed oil and saw palmetto extract for hair loss. The user has been using minoxidil, derma rolling, vitamin D, and biotin but is considering finasteride next.

A 29-year-old woman is experiencing gradual hair thinning since age 15, suspects Androgenic Alopecia, and has tried 5% minoxidil with little success. She has purchased various hair loss treatments including minoxidil, dutasteride, finasteride, and spironolactone, but is cautious about starting them due to potential interactions with her ADHD medication.

The post and conversation are about HMI-115, a potential treatment for hair loss. The conclusion is that HMI-115 is not a 5ar-inhibitor and is instead a prolactin receptor inhibitor. Some users are skeptical about its effectiveness and believe that baldness will still be a problem in the future.

User shared progress of two years using 1mg daily Finasteride and 2x weekly microneedling for hair loss. Many users praised the results and discussed their own experiences with microneedling and Finasteride.

The user's experience taking Pyrilutamide, a drug for hair loss treatment, and their use of it in combination with other treatments such as Minoxidil, Finasteride and RU58841. They have experienced positive results so far with no major side effects.

The potential of verteporfin to heal wounds without scarring; however, despite its promising preclinical trials and coverage from a major media outlet, there is still no official clinical trial result and the drug has only garnered attention from hair loss communities.

Pyrilutamide, a new drug being tested to combat hair loss that has been found to perform comparably or better than finasteride and dutasteride in the initial 6 months of treatment with minimal reported side effects.

Vitamin C mixed with shampoo stopped shedding and promoted hair regrowth after 1.5 years. Both the person and their wife experienced significant hair loss reduction with this method.

The conversation discusses expectations for the release of Breezula, a new hair loss treatment, and compares it to existing treatments like finasteride. Some believe Breezula could be a game-changer due to fewer side effects, while others await more permanent solutions like hair follicle cloning.

The conversation discusses GT20029, a new topical drug for hair loss and acne without notable side effects, which has been accepted for investigational use in China. Some users express skepticism about the legitimacy of the company and the potential for other drugs like RU58841 to be developed due to patent expiration and lack of profitability.

The user experiences severe anxiety and physical symptoms after taking finasteride and is seeking alternative hair loss treatments since dutasteride is unavailable. They suspect an allergic reaction to finasteride and have stopped using it.

The conversation discusses the availability of GT20029, a new topical hair loss treatment with fewer side effects than Minoxidil or finasteride. Users suggest using finasteride to preserve hair until GT20029 becomes available.

The user experienced concerning side effects like throat irritation, shortness of breath, chest pain, and testicle pain after using RU58841 for hair loss, despite also using finasteride and minoxidil. Other users shared mixed experiences, with one advising to stop using RU58841 due to similar side effects, while another reported significant hair loss reduction without side effects.

A user shared their successful hair regrowth routine, which includes finasteride, derma rolling, minoxidil (Rogaine), biotin pills, and vitamin D supplementation, and saw noticeable results in 3 months. They suggest this routine as a variation of the "Big 3" hair loss treatments and have created a website to sell the products they used.

A 36-year-old is concerned about early hairline recession despite no family history of hair loss. They are considering treatments like finasteride, minoxidil, and ketoconazole shampoo but are worried about potential side effects and are seeking natural alternatives.

PP405, a potential treatment for male pattern baldness, shows promise with some participants experiencing hair regrowth in early trials. However, it is not yet considered a cure and may be used alongside existing treatments like minoxidil and finasteride.

The conversation is about the delay in receiving updates on the HMI-115 phase 1 trial for hair loss. No specific treatments are mentioned in the conversation.

Many users criticize advice on forums that suggest shaving heads instead of trying treatments like finasteride for hair loss. They argue that maintaining hair is important for self-esteem and dating success, and that baldness often requires compensating with other attributes.

A drug that regrows body parts, but not hair, sparking debate on hair loss treatments. Discussions include the use of finasteride, dutasteride, and the potential for new methods to restore hair.

PP405 may not need daily use like minoxidil, but finasteride might still be needed to maintain hair regrowth. PP405 reawakens dormant hair follicles, potentially offering a long-term solution, though not a permanent cure.