A user has been using dutasteride, RU58841, minoxidil, and ketoconazole for 2 years with no progress and worsening hair recession. They seek advice on how to proceed.
Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.
A user is documenting their natural approach to treating a receding hairline using a dermastamp, essential oils (rosemary oil at 3% dilution with pumpkin seed oil), a multivitamin with vitamin D, and daily collagen shakes. They acknowledge the common recommendations of minoxidil and finasteride but prefer to test natural methods and share their results.
Oral minoxidil can cause severe side effects, including heart issues, even at low doses. Users suggest starting with a lower dose or using topical treatments to minimize risks.
The user noticed new baby hairs after using sulforaphane but is still experiencing shedding. They are seeking a supplement to stop shedding, possibly grape seed extract.
A 43-year-old experienced gynecomastia after 20 years of taking dutasteride and 7.5mg oral minoxidil. Suggestions include consulting an endocrinologist, checking hormones, and considering Nolvadex or DIM supplements.
Using a blunt tip syringe is an effective method for applying liquid topicals like minoxidil and RU58841, especially for those with thick or long hair experiencing diffuse thinning. The user found significant hair regrowth and increased density after using these topicals for less than three months.
A user experienced significant hair regrowth and stopped hairloss after taking 0.5mg of dutasteride daily for a month, without using minoxidil. They reported no side effects and were pleased with the results.
A 25-year-old is struggling with hairloss despite using treatments like oral Minoxidil, oral and topical Finasteride, Dutasteride, and PRP sessions. They feel frustrated with inconsistent treatment strategies and are seeking advice on managing thin hair and regaining confidence.
A user reported that after experiencing hair thinning, they started using finasteride in 2024 and later began GHK-Cu peptide injections in March 2026, which they believe stopped their hairloss and made their hair feel thicker. The user shared their experience despite receiving criticism for not solely endorsing finasteride.
The user has been using oral minoxidil for 4 years and durum wheat 3 days a week for 7 months, but is experiencing increased hairloss when washing hair. They suspect it might be due to decreased DHT levels and are seeking similar experiences from others.
Hairloss significantly impacts self-perception and attractiveness, with treatments like finasteride, minoxidil, and hair transplants suggested. The conversation highlights the emotional struggle and societal perceptions tied to hairloss.
A 20-year-old is experiencing hairloss and is using finasteride, ketoconazole, and topical minoxidil. They suspect retrograde alopecia due to hairloss on the sides and nape, despite noticing some hair thickening on top.
Hairloss treatments include topical and oral minoxidil, low-level laser light therapy, and peptide serums. Bryan Johnson avoids finasteride and dutasteride due to potential side effects, focusing instead on his own protocol with these treatments.
A 31-year-old man feels depressed due to hairloss, using topical finasteride and previously tried minoxidil. Others suggest treatments like finasteride, minoxidil, hair transplants, or embracing baldness, highlighting the importance of mental health and self-acceptance.
Hairloss treatments like Breezula and PP405 are delayed, with approvals taking years, while existing treatments like minoxidil and finasteride remain popular. New treatments like Clascoterone and Veradermics are in trials, but high costs and lengthy approval processes slow their release.
Hairloss treatments like Minoxidil, finasteride, and potential mRNA therapies are discussed. There is skepticism about targeting specific genes due to the complex genetic nature of hairloss.
Hairloss treatments are being tested on mice, with methods like minoxidil and stem cell therapy showing promising results. However, human trials are still years away, leading to humorous frustration about mice benefiting first.
Hairloss changes are typically noticed over months or years, not days, and treatments like finasteride, dutasteride, and minoxidil require time to show effects. People often overreact to daily shedding, but realistic expectations and patience are necessary for hair regrowth treatments.
Hairloss may be linked to the TRPS1 gene and protein, not just DHT. Amplifica's AMP-303 targets mesenchymal stem cells and shows promise in treating hairloss, unlike Pelage's PP405.
Hairloss returned after 8 months of using a treatment with .3% Dutasteride and 8% Minoxidil. The user suspects a marketing strategy as the company offers a more expensive product with additional ingredients like biotin and finasteride.
Hairloss involves more than just DHT, with genetic factors like TRPS affecting hair follicles. Treatments such as Amplifica's AMP-601 and AMP-303 target stem cells for potential hair growth solutions.
Hairloss has slowed or stopped after 5 months of daily oral minoxidil and finasteride treatment, with ketoconazole shampoo used twice a week. Noticeable thickening is observed, especially on the mid scalp.
Finasteride and Dutasteride do not cause depression or mood disorders; hairloss itself may be a more significant factor. Some users experience side effects from Finasteride, but it is generally well-tolerated.
Lowering DHT can improve skin quality and reduce scalp issues. Finasteride is effective for hair regrowth and improving skin texture, while dutasteride may increase oiliness and shedding for some users.
Hairloss requires proper diagnosis as it can have various causes, and treatments like finasteride, minoxidil, and dutasteride are often used. Many people express frustration with dermatologists and turn to self-research and alternative sources for treatment.
Hairloss is linked to a higher rate of body dysmorphic disorder (BDD), OCD, and depression. Finasteride and dutasteride are not linked to increased suicidal risk, though some users report mental health side effects.
Hair growth relies on mechanical forces, not just chemicals, with tissue acting like a motor. Minoxidil and finasteride help, but maintaining tissue elasticity and addressing mechanical issues are essential.