Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hairloss by blocking DHT and promoting hair growth.
Hair regrowth using estradiol, spironolactone, minoxidil, and finasteride, showing significant improvement over four years. HRT is not advised for cis men solely for hairloss due to feminizing effects.
Koshine 826 (Pyrilutamide) is being used by several users to address hairloss, with mixed results on shedding and side effects. Some users report reduced shedding and no side effects, while others experience increased shedding and potential issues with libido and erectile dysfunction.
A user is excited to start using Pyriltamide for hairloss after experiencing side effects from topical finasteride. Other users discuss the potential and skepticism of Pyriltamide compared to older treatments like finasteride and RU58841.
The user has been using finasteride daily since 2020, dutasteride twice weekly since September, 2.5 mg oral minoxidil daily, microneedling monthly, and ketoconazole semi-often. They are feeling lost about their hairloss progress after one year on this regimen.
The post and conversation discuss KX-826 (pyrilutamide) for hairloss treatment, with positive remarks about its advertising and authenticity in China. The user changed their perspective after further research and seeing genuine advertising.
A user is considering using ketoconazole shampoo for hairloss and is seeking feedback on its effectiveness. They are asking for before and after photos or success stories.
The post discusses a user's 2-month progress in treating hairloss using topical Du once a week, microneedling, and red light therapy. The user notes that red light therapy is primarily for face and body inflammation but also applies it to the scalp.
The conversation discusses topical androgen receptor blockers for hairloss, mentioning Clascoterone, Pyrilutamide, GT20029, and RU58841. Ketoconazole's effectiveness and application methods are also debated.
The conversation is about someone's progress with hairloss treatment using Minoxidil, Finasteride, Ketoconazole, and oils. They shared progress pictures to show the results.
The user is using topical finasteride and minoxidil for hairloss and is considering adding rosemary oil, castor oil, and stemoxydine to their routine. They are asking if anyone has experience with this combination or a similar one.
A user started taking finasteride three months ago to treat hairloss and unexpectedly cleared their acne, which they had been struggling with since age 12. The conversation includes others sharing their experiences with finasteride, its effects on acne and hairloss, and mentions a related treatment, clascoterone, for acne and hairloss.
The conversation discusses the effectiveness and safety of hairloss treatments, specifically RU58841 and Pyrilutimide (Pyril), with users sharing that Pyril was no more effective than a placebo and expressing concerns about the safety of RU58841 based on personal experiences and the lack of pharmaceutical interest.
The user started using 0.05% topical finasteride and minoxidil for hairloss treatment on December 15, also incorporating dermarolling and rosemary oil, and is satisfied with the visible improvement in their receding hairline. Another user inquired about where to obtain topical finasteride.
The user has been using finasteride for five years and minoxidil foam for 1.5 years to combat hairloss, experiencing significant regrowth after an initial shedding phase with minoxidil. They shared progress pictures and discussed treatment experiences, including the addition of minoxidil to their regimen after noticing reduced efficacy with finasteride alone.
Users discussed the convenience and effectiveness of Hims Fin+Min chewable tablets for hairloss. Some believe it's overpriced compared to traditional oral finasteride and minoxidil, while others find it more convenient and potentially more effective.
User GreatCanuck experienced hair regrowth after using finasteride for a year, reducing anxiety about hairloss. Others in the conversation shared similar positive experiences and discussed family members using the treatment.
User tried topical and oral finasteride and oral minoxidil for hairloss without success. ButterscotchSea3159 suggests using Dutasteride, oral minoxidil, ketoconazole shampoo, microneedling, and possibly RU for better results.
Low-Butterscotch-608's progress in treating their hairloss with finasteride and minoxidil over the course of two years, as well as opinions on whether they should consider a hair transplant to address further receding. Replies included advice about adding microneedling to the protocol.
The conversation discusses the effectiveness of anti-androgens for hairloss, with a preference for topical treatments like RU58841 over oral options due to better scalp concentration and fewer side effects. Topical finasteride at 0.1% may provide some results, especially when combined with a topical androgen receptor antagonist like RU58841.
Pyrilutamide, a potentially effective hairloss treatment; other topical treatments like RU58841 and CB-03-01 that may have fewer side effects than Pyrilutamide; and the Phase 3 clinical trials of Pyrilutamide, which is likely to be approved by the FDA soon.
A user's 10-month progress update using finasteride and minoxidil to treat hairloss, with other users offering congratulations, jokes, advice, and questions.
A user had a bad reaction to Finasteride, experiencing anxiety and fatigue, and is seeking alternative hairloss treatments since they can't use Finasteride or Minoxidil. Suggestions include trying low doses of Finasteride, making a topical version, or using other treatments like Alfatradiol, but the user is hesitant to use Finasteride again and is considering a hair transplant.
The conversation is about seeking alternatives to finasteride for hairloss treatment due to concerns about sexual side effects, with pyrilutamide mentioned as a potential alternative.
This user has conducted data scraping of 365 Reddit posts on the hairloss drug Pyrilutamide over the last year to analyse efficacy and side effects. The findings, which are available in a 19 page report with graphs, suggest that 22% of Pyrilutamide users experience positive results while 63% experience symptoms. A larger analytics project is proposed for other drugs with enough demand.
Pyrilutamide, a potential hairloss treatment that is currently in development and may be available soon; an androgen receptor degrader which is also being developed as a potential treatment for hairloss; and the comparison between Pyrilutamide, finasteride, minoxidil, and RU58841.
The conversation discusses the potential of a new hairloss treatment, GT20029, which targets androgen receptors in the scalp and is in phase 1 trials in China. Users express hope that this treatment will be more effective than current options like Minoxidil and Finasteride.
A user who has had positive results from using finasteride, minoxidil and microneedling for hairloss over the past two years. Replies to this post congratulated the user on their progress and praised them for their success.
KX-826 (Pyrilutamide) being tested in the US for hairloss treatment and that they have found enough people to participate in phase II clinical trials. Other treatments discussed are Minoxidil, finasteride, and RU58841.