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CBD in an emu and lanolin oil preparation showed a 100% increase in hair growth, but the effectiveness may partly come from the oils. Users discussed proper CBD dosage, preparation methods, and skepticism about the study's quality.

The conversation concludes that finasteride, a 5α-Reductase inhibitor used for hair loss, does not impair cognition either short-term or long-term. It suggests "brain fog" is not caused by the medication.

The conversation is about creating a higher concentration of the newly FDA-approved hair loss treatment, Clascoterone (Winlevi), through compounding pharmacies and possibly organizing group purchases. Some users are unfamiliar with Winlevi and are asking for an explanation of the drug.

Whether using both Fluridil and Alfatradiol together could be more effective than either one alone as a hair loss treatment, given their different mechanisms of action.

A user applied a homemade topical finasteride solution daily for 35 days, reducing hair shedding significantly with minimal side effects. They plan to continue for 90 days and will provide further updates.

The user has been using finasteride and minoxidil for over three years, switched to oral minoxidil, and recently started dutasteride and dermarolling but still experiences thin hair. They are seeking suggestions for improving their hair condition.

Despite using treatments like Dutasteride, Minoxidil, RU58841, and GHK-Cu injections, the individual continues to experience aggressive hair thinning and is seeking a specialist for further help. Suggestions include trying finasteride, dermarolling, or another hair transplant.

A 26-year-old is considering embracing baldness after mixed results and side effects from using dutasteride, minoxidil, and finasteride for hair loss. Suggestions include trying new hairstyles, considering a hair transplant, or focusing on self-acceptance.

Taking 5mg oral minoxidil at night instead of splitting 2.5mg doses, with the rationale that a single larger dose may provide a stronger activation for hair follicles and reduce peak-related side effects. Some users report sleep issues with nighttime dosing, while others find it beneficial; opinions on effectiveness and side effects vary.

The user started finasteride and minoxidil in 2023 and added other treatments like ketoconazole shampoo and a Theradome helmet, noting some improvement but also experiencing fluctuations in hair density. They are considering adding low-dose dutasteride to their regimen and are seeking advice on distinguishing between normal hair changes and actual hair loss progression.

A user shared their 75-day progress using oral minoxidil, finasteride, ketoconazole shampoo, and dermastamping for retrograde alopecia, reporting significant improvement and increased body hair without side effects. They also discussed quitting smoking and the potential correlation between early beard growth and male pattern baldness.

A 24-year-old male has been using oral Minoxidil (2.5mg daily) and daily Dutasteride for hair loss, noticing slight thickening but no major regrowth. Users suggest increasing Minoxidil dosage to 5mg and maintaining consistency, with some recommending additional treatments like topical Minoxidil or considering a hair transplant in the future.

Switching from finasteride to dutasteride can lead to varied results, with some experiencing better hair regrowth and fewer side effects, while others continue to lose hair. Dutasteride is generally seen as more effective but has a longer half-life, potentially extending side effects.

A 43-year-old male has been using oral minoxidil, finasteride, and dutasteride for hair loss, with some stabilization and thin hair growth but no significant cosmetic improvement. He is considering increasing microneedling frequency and exploring other options, as he is concerned about the lack of terminal hair growth.

The user has high DHT levels despite using dutasteride, which may not be effective due to potential damage or spoilage. They are considering a hair transplant if DHT levels don't decrease after two years.

A 26-year-old male shares his progress using 0.5mg finasteride and 5% topical minoxidil for hair loss, considering transitioning to 3mg oral minoxidil. He is also contemplating using a hair system to boost confidence while continuing treatment.

A 24-year-old male is using topical Minoxidil and Finasteride, along with microneedling, to address hair loss and is seeing some improvement, though it's early in the treatment process. The user is advised to continue the regimen for at least 12 months for a clearer assessment, with some recovery possibly due to resolving telogen effluvium from a previous caloric deficit.

Clascoterone 5% topical solution is effective and safe for long-term use in treating male pattern hair loss. Cosmo Pharma aims for EU and US approval, with a potential US release in late 2027 or early 2028.

The user has been using minoxidil and finasteride for nearly two years, seeing some prevention of further hair loss and possible regrowth. Many suggest trying dutasteride or considering a hair transplant as the next step.

A user shared progress after 5 months on oral finasteride (1mg) and minoxidil (2.5mg), noting improvements despite minimal temple growth. They experienced shedding initially but reported no side effects, and others shared similar experiences and additional treatments like hair serums.

A user shared a DIY recipe for a NutraKos-style amino acid mix as a cost-effective alternative to the expensive product, suggesting it as a complementary supplement for hair loss. Another user argued that proven treatments like finasteride and minoxidil are more reliable, questioning the efficacy of the amino acid mix.

A 31-year-old has been using 1mg finasteride, 5mg minoxidil, minoxidil spray, a dermaroller, and Nizoral shampoo for hair regrowth. The treatments have resulted in thick, healthy hair, and the user has been on finasteride since 2022, switching from lotion to pills in 2025.

A user is anxious about shedding after starting oral finasteride and topical minoxidil, noting about 250 hairs lost after washing. Responses suggest that shedding is common with these treatments, especially with curly hair, and that it often peaks around 8-10 weeks before improving.

The user has been using finasteride for six years and minoxidil for three years with no noticeable hair regrowth. Suggestions include switching to dutasteride, considering a hair transplant, and trying microneedling.

Pelage plans to conduct two Phase 3 trials for PP405, a new hair loss treatment, which may take about a year to complete. Users discuss various hair loss treatments, including pyrilutamide, minoxidil, finasteride, and clascoterone, with some expressing impatience over the lengthy trial process compared to faster drug approvals like the COVID vaccine.

Finasteride is preferred for its shorter half-life and FDA approval, while dutasteride is seen as more effective but not FDA-approved for hair loss. Many combine these with minoxidil for improved results, though side effects and effectiveness vary.

The conversation discusses the potential for developing a biologic "DHT sponge" to neutralize DHT in the bloodstream as a treatment for hair loss, suggesting it could be more targeted and have fewer side effects than current treatments like finasteride and dutasteride. Concerns include the complexity, cost, and potential side effects of such a treatment, as well as skepticism about its feasibility and market interest.

Topical dutasteride, particularly at 0.05%, shows greater hair density improvement than oral finasteride over 24 weeks, though hair thickness gains are similar. Some users report side effects with topical treatments, but others find them effective for maintaining hair without significant systemic absorption.

PP405 and ABS-201 are promising treatments for male pattern baldness. PP405 shows rapid hair growth in human trials, while ABS-201 shows significant regrowth in animal studies but is still in early human trials.

The user has been taking 1mg of finasteride daily for a year, maintaining hair density without regrowth. They are considering oral minoxidil for regrowth, avoiding topical minoxidil due to its toxicity to cats, despite concerns about heart side effects.