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GlossaryHair Shaft Production

process of forming and growing hair from follicles

Hair Shaft Production refers to the process by which hair is formed and grows from the hair follicle. This involves the division and differentiation of cells in the hair bulb, which is located at the base of the follicle. These cells produce keratin, a protein that makes up the hair shaft, which then extends out through the skin. This process is regulated by various genetic, hormonal, and environmental factors.

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Tracking 154 products like 278 Mane Regain - RU58841 5% Solution, 285 Multi-Peptide Serum for Hair Density, 286 Hair Growth Actives 18% Hair Serum, 287 iRESTORE Scalp Serum and 289 Hair Loss Conditioner for Men from by companies like Amazon. View all 154 products »

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community SCUBE3 and GT20029 could be the closet thing to a cure: Hair Follicle Regeneration and Protection Against DHT

in Research/Science 14 upvotes 2 years ago

SCUBE3 and GT20029 are potential treatments for hair loss, with SCUBE3 stimulating hair growth and GT20029 protecting against DHT. A combined approach using SCUBE3, finasteride or dutasteride, and later GT20029 could provide a comprehensive treatment for androgenetic alopecia.

community The Health Benefits of Head Hair

in Research/Science 19 upvotes 6 months ago

Hair provides protection against head trauma, reduces skin cancer risk, helps remove heavy metals, and aids in wound healing. The conversation emphasizes the health benefits of maintaining head hair beyond cosmetic reasons.

community Sebum production even on dutasteride, and its relation to MPB.

in Finasteride/Dutasteride 6 upvotes 4 months ago

The conversation discusses managing hair loss and scalp issues, with users sharing experiences using treatments like dutasteride, finasteride, ketoconazole, sulfur soap, and topical anti-androgens. Suggestions include trying sulfur soap, scalp massages, spironolactone, and dietary changes to reduce sebum production and dandruff.

community Very agressive protection / regrowth stack on steroids

in Journals / Progress Pictures 223 upvotes 3 months ago

A 24-year-old with hair thinning is using a regimen including dutasteride, RU58841, HGH, GHK-cu, and other compounds to protect and regrow hair. They are also incorporating a mild cutting cycle with testosterone propionate, anavar, and tirzepatide.

community RU58841 to stop excessive oil production?

in Research/Science 7 upvotes 1 year ago

The user discusses using Minoxidil for hair loss and is considering RU58841 to reduce excessive oil production. They seek advice on RU58841's effectiveness in blocking sebum production.

community Explanation for "dutasteride destroyed my hair"

in Finasteride/Dutasteride 9 upvotes 1 year ago

Dutasteride can drastically reduce sebum production, leading to dryer hair and shedding. Alternating shampoos and periodic silica supplementation can improve hair quality and thickness.

community Prediction: Scube3 is never coming out

in Research/Science 6 upvotes 2 years ago

Scube3, a potential hair loss treatment, is unlikely to be released because it was given to a startup company, Amplifica, which may go bankrupt and fail to bring the treatment to market. Amplifica is prioritizing other treatments over Scube3, which could lead to financial loss and the end of Scube3's development.

community Oral minoxidil and collagen production- does anybody else believe there’s a real link?

in Minoxidil 7 upvotes 2 years ago

The conversation discusses the user's experience with oral minoxidil for hair loss and a possible increase in facial wrinkles, leading to a plan to ask for a tretinoin prescription. Specific treatments mentioned are oral minoxidil and the intention to use tretinoin.

community Hair Multiplication Projects in China - Promising clinical trial results on Mice

in Technology 35 upvotes 10 months ago

A breakthrough in hair follicle cultivation using induced pluripotent stem cells (iPSCs) has been achieved, producing large hair follicles suitable for transplantation. Clinical trials for this hair multiplication technology are planned in partnership with Yinguan Biotechnology.

community possible treatment of AGA and change in sebaceous gland condition and oil production using sulfur soap

in Research/Science 4 upvotes 6 months ago

Sulfur soap may help with hair thickening and reducing scalp inflammation, but it can cause dryness. Nizoral, containing ketoconazole, is noted for its potential to reduce seborrheic dermatitis but may also cause scalp dryness and hair loss.

community The day they make a pill that only targets DHT production in the scalp

in Finasteride/Dutasteride 29 upvotes 1 year ago

Reducing DHT in the scalp is ideal for hair retention, with topical finasteride and dutasteride being common treatments. Some users report side effects like reduced libido, while others experiment with higher doses for regrowth.

community Update: A New Therapeutic Channel - Hair Follicle Glucose Metabolism

in Research/Science 10 upvotes 3 years ago

Hair loss can be treated by correcting glucose metabolism in hair follicles and using equol as a safer DHT blocker. Production of these treatments is starting soon, and a Discord channel is available for more information.

community 5 alpha reductase type 1 is in brain tissue producing the main endogenous gabaergic allopregnanolone, not 2. How can finasteride as a 5ar2 lower that?

in Finasteride/Dutasteride 29 upvotes 1 year ago

Finasteride and dutasteride are discussed for hair loss, with concerns about their effects on neurosteroids and potential side effects like depression. Alternatives like topical estrogen and lifestyle changes are considered, with varying opinions on mental health and hair regrowth.

community PP405: The Ultimate Hair Loss Drug for Complete Hair Growth

in Research/Science 211 upvotes 1 year ago

PP405 is a new hair loss treatment in phase 2 trials that may promote hair growth by increasing lactate production and activating hair follicle stem cells. It could potentially replace hormone-disrupting treatments like Minoxidil and finasteride.

community Hypothetically, if estradiol has been a "cure" for hair loss, could one apply estradiol topically and just take an estrogen blocker and/or testosterone to offset the systematic effects?

in Research/Science 7 upvotes 1 year ago

Topical estradiol may help with hair loss but can have systemic effects, like reduced testosterone production. Using estrogen blockers can have negative side effects, such as joint pain and reduced sex drive.

community Dutasteride and my semen production

in Finasteride/Dutasteride 74 upvotes 1 year ago

A user experienced sexual side effects, including reduced semen production and numbness, after switching from finasteride to dutasteride for hair loss. They decided to stop dutasteride to prioritize their sexual health and may return to finasteride if issues resolve.

community When will Chinese manufacturers start producing Clascoterone 5%?

in Treatment 5 upvotes 3 months ago

The conversation discusses the anticipation of Chinese manufacturers producing Clascoterone 5% before its full approval in 2027. It also mentions treatments like Minoxidil, finasteride, and RU58841 for hair loss.

community Couple of questions for hair fiber users

in Product 6 upvotes 4 years ago

User plans to use hair fibers regularly and asks about re-application, consistency, rain protection, and Boldify vs Toppik. Others provide advice and share experiences.

community Why does Finasteride make my hair not get greasy fast anymore?

in Finasteride/Dutasteride 31 upvotes 1 year ago

Finasteride, a hair loss treatment, was observed to reduce scalp oiliness in users. Anti-androgens like Finasteride are known to decrease the activity of oil-producing glands.

community I have not seen a single person who claims dutasteride destroyed their hair post a picture of the before/after

in Finasteride/Dutasteride 123 upvotes 1 year ago

The conversation discusses skepticism around claims that dutasteride worsens hair loss, with some users suggesting misinformation or panic during shedding as reasons for such claims. One user shared their negative experience with dutasteride, including increased sebum production and hair loss, and is now considering a higher dose of oral minoxidil after stopping dutasteride.

community My brain absorbing the assorted off label drugs I put near it on a daily basis just for maximum keratin production

in Satire 25 upvotes 1 year ago

The conversation humorously discusses using off-label drugs like Minoxidil, finasteride, and RU58841 for hair growth. It jokes about the brain absorbing these treatments for maximum keratin production.

community Claim: Insulin resistance increases the enzyme that creates DHT and affects the liver's ability to control hormones

in Research/Science 4 upvotes 5 months ago

Insulin resistance may increase DHT production, contributing to hair loss, and addressing it through diet, nutrients, and natural DHT blockers like saw palmetto and pumpkin seed oil could help reverse hair loss. Some users prefer medications like finasteride for more effective results.

community microneedling, do the gains go away?

in Microneedling 23 upvotes 3 years ago

Microneedling promotes hair growth by increasing circulation and collagen production, with gains potentially lasting longer than those from minoxidil. Some users report sustained results after stopping microneedling, unlike with minoxidil and finasteride.

community how about progesterone cream?

in Research/Science 22 upvotes 1 year ago

Progesterone cream might help with hair loss by inhibiting DHT production and suppressing prolactin, which can increase DHT. Some dermatologists have used progesterone for hair loss treatment, and it has been effective, sometimes combined with minoxidil, finasteride, and hydrocortisone.

community Finasteride, Dutasteride, Pyrilutamide, RU58841 all accomplish the same thing in your body. Why skip around?

in Treatment 2 years ago

Hair loss treatments Finasteride, Dutasteride, Pyrilutamide, and RU58841 have different mechanisms of action. They can be used individually or stacked for better protection against hair loss.

community HMI-115 question about potential earliest access

in Research/Science 8 upvotes 3 years ago

Hair loss treatments discussed include Minoxidil, Finasteride, and RU58841. HMI-115, a monoclonal antibody drug, is in phase 1 and 2 trials for different conditions, but its availability on the gray market is unlikely due to high production costs.

community Progress update: 4 months 10days of using topical minoxidil.

in Is this regrowth? 46 upvotes 9 months ago

The user experienced hair regrowth after using 5% topical minoxidil for over four months, despite initial shedding. They apply it once daily but occasionally skip days due to concerns about collagen production interference.

community is my multi vitamin a high dose ?

in Finasteride/Dutasteride 5 upvotes 1 year ago

User experienced hair loss after weight loss and started using finasteride 1mg and a multivitamin called HAIRGRO. They noticed increased oily skin and sebum production and are unsure if they should continue the multivitamin.

community My experience with Pyrilutamide

in Update 3 upvotes 2 years ago

The user experienced a slight decrease in hair shedding and scalp itch, and reduced sebum production using Pyrilutamide, but stopped due to chest pain, breathing difficulties, and heart issues. They felt normal a week after discontinuing and doubted FDA approval for the drug.

community Microneedling protocol and supplements

in Microneedling 2 years ago

Microneedling for hair loss should avoid anti-inflammatory supplements like garlic, Vitamin E, fish oil, turmeric, and NSAIDs for 3 days before and 5 days after the procedure to enhance collagen production. Completely abstaining from these supplements may be unnecessary, but caution is advised around the procedure time.