PP405 is a topical gel being tested for hairregrowth in adults with androgenetic alopecia. Volunteers aged 18-55 are needed for a 16-week trial in several US locations.
The user shared progress pictures showing hairregrowth using Minoxidil, finasteride, rosemary mint oil, biotin, and vitamins. Responses praised the results, though one user doubted the effectiveness of rosemary and biotin.
A user is frustrated with slow and thin hairregrowth at the temples despite using Minoxidil for six months, along with dermastamping, oiling, vitamins, and exercise. They are seeking advice on why vellus hairs are not thickening.
A user shared a 3.5-month hairregrowth progress using Minoxidil, ketoconazole, and dermarolling, and has started taking oral finasteride to maintain gains. There was a significant initial hair shed, which is normal for these treatments.
A user shared their successful hairregrowth using a combination of derma stamping, Retinol, Minoxidil, Dutasteride, and RU58841, with no side effects. Others discussed their varied experiences with these treatments, including concerns about potential side effects like heart issues and sexual dysfunction.
Finasteride may cause hair shedding as part of the regrowth process, but there are no controlled trials confirming this. The shedding idea is mostly based on anecdotal reports and comparisons to how minoxidil works.
The user added microneedling to their routine of minoxidil and finasteride, resulting in noticeable hairregrowth after three months. They shared photos showing significant improvement.
The user applied minoxidil and finasteride topically for hairregrowth, experiencing significant results but stopped finasteride due to side effects. They later added stevia to minoxidil, noticing potential improvement in hair density, particularly at the front.
Dutasteride is preferred over finasteride for hair loss due to fewer side effects. Combining dutasteride with minoxidil and RU58841 is effective for hairregrowth, even during steroid use.
The user experienced serious hair loss and started using finasteride, minoxidil, microneedling, and argan/rosemary oil. They are asking if they can maintain hairregrowth by stopping minoxidil and continuing only with finasteride and microneedling.
Vitamin C mixed with shampoo stopped shedding and promoted hairregrowth after 1.5 years. Both the person and their wife experienced significant hair loss reduction with this method.
Breezula protects hair follicles from both testosterone and DHT, unlike finasteride, which only protects against DHT. This could potentially lead to significant hairregrowth, similar to results seen in transgender individuals using hormone blockers.
The post and conversation are about a user's successful regrowth of hair using topical minoxidil and rosemary shampoo. Other users discuss the potential limitations of minoxidil and recommend using finasteride to maintain hair growth.
Dutasteride is often seen as more effective than finasteride for hairregrowth, but it may cause initial shedding and takes longer to work. Combining it with treatments like minoxidil can improve results, though experiences vary.
Oleic acid and microneedling are being explored for hairregrowth, but results are mixed. Addressing DHT and fibrosis is crucial, with treatments like finasteride, minoxidil, and scalp massage also discussed.
The conversation humorously suggests using immunosuppressants like ciclosporine and oral minoxidil for hairregrowth, with a satirical plan involving hair transplants from family members. It highlights the side effects and impracticality of such treatments, emphasizing the post's satirical nature.
Switching from finasteride to dutasteride may be more effective for hairregrowth due to dutasteride's stronger enzyme inhibition, but combining both drugs could enhance results. Some users report better outcomes with dutasteride, while others recommend a gradual transition to prevent potential hair loss.
Oleic acid and ethanol are being considered for hairregrowth, with some users planning to self-experiment. There is skepticism about their effectiveness, and ongoing use of treatments like finasteride and minoxidil is mentioned.
PP405 targets hair follicle stem cells differently than exercise-induced lactate, suggesting exercise alone may not replicate its benefits. Minoxidil and finasteride are recommended alongside exercise for hairregrowth, with additional suggestions like spicy food and infrared exposure.
Low-level laser therapy (LLLT) is debated for hairregrowth, with some users suggesting it should be combined with treatments like minoxidil and finasteride for effectiveness. Many users express skepticism about LLLT's efficacy and cost, emphasizing the need for the correct wavelength and quality devices.
The user experienced subtle hair growth improvements using finasteride, dutasteride, and minoxidil over nearly three years, with notable progress at the temples. The front hairline shows quicker regrowth cycles, but the vertex and crown remain unchanged.
The conversation is about people with advanced hair loss (Norwood 6 or 7) who have seen significant hairregrowth using treatments like finasteride, minoxidil, microneedling, and RU58841. Nine cases were collected to motivate others to try these treatments despite advanced hair loss.
User redh0t12 suggests using a derma pen for hairregrowth, as it helped them after using finasteride and minoxidil. Others discuss their experiences with various treatments, including derma rolling, oral and topical minoxidil, and finasteride, with mixed results.
A user shared their experience with DIY PRP scalp injections for hairregrowth, using an EZ Injector and other at-home equipment. Another user reported success with at-home PRP treatments for 1.5 years, noting thicker hair and a stable hairline.
Tretinoin can increase hair follicles and is used alongside minoxidil and finasteride for hair growth, though it may cause skin peeling. Users report varying results, with some experiencing regrowth and others questioning its efficacy for hair.
The DHT itch is linked to hair loss and persists despite finasteride use; switching to dutasteride helped alleviate the itch and promoted regrowth. Some users suggest seborrheic dermatitis as a cause and recommend treatments like medicated shampoos, vitamin D, and minoxidil.
Oral minoxidil is effective for hair loss and unlikely to significantly affect collagen synthesis, making it a safe option without causing premature skin aging. Users report positive hairregrowth without noticeable skin aging.
Minoxidil and finasteride can both cause initial hair shedding, but they work differently; minoxidil promotes hair growth, while finasteride improves the hormonal environment. Starting finasteride after minoxidil may trigger additional shedding, but it often leads to improved regrowth.
A 21-year-old started taking 1mg Finasteride daily for hair loss and considered adding Minoxidil for temple regrowth, questioning if stopping Minoxidil would cause hair loss despite continued Finasteride use. Responses suggest Minoxidil-induced hair requires ongoing use to maintain, while Finasteride alone may not sustain Minoxidil gains, with some recommending microneedling or topical applications to enhance results.
Finasteride prevents further hair loss by blocking DHT, while minoxidil stimulates hair growth by prolonging the active phase of hair follicles. Stopping minoxidil can lead to loss of regrown hair because finasteride does not address the same growth mechanism.