Oral minoxidil and dutasteride are used for hair loss with mixed results. Some users report new growth, while others suggest scalp inflammation may be an issue.
A user humorously suggested smoking minoxidil in a blunt as an alternative hairgrowth method, sparking a satirical discussion on unconventional and unsafe ways to use minoxidil. The conversation included various suggestions like oral pills, rectal administration, and other absurd methods, with some users warning against the dangers of such practices.
Moringa extract and oil are suggested to help with hair loss, with some users combining it with treatments like minoxidil, finasteride, and dutasteride. Moringa is claimed to improve hairgrowth and health, but evidence is mostly anecdotal.
User TopBack56 and friends tried pyrilutamide (KX-826) for hair loss without experiencing negative side effects. They observed fine vellus hairs but no thick hairgrowth yet, and plan to add GT20029 to their regime after safety trials.
The post and conversation are about the role of the enzyme 3alpha-hydroxysteroid reductase in hair loss and the potential of compounds like procyanidin B2 and sulforaphane to boost its activity for hair regrowth. Further research is needed to develop effective treatments based on this theory.
A user used oral finasteride and minoxidil for hair loss, seeing new hairgrowth under a microscope but no visible change. Commenters debated if the growth was real hair or fibers, and the user will update every 90 days.
The regimen for hair loss includes topical finasteride, clascoterone, tretinoin, minoxidil, oral saw palmetto, beta-sitosterol, vitamin D, microneedling, and anti-fungal shampoo. Expected benefits are increased hairgrowth and density, with considerations for potential skin irritation and interactions between treatments.
Capronium Chloride and Trichoxidil are suggested as better alternatives to Minoxidil for hairgrowth without heart side effects. The Japanese Dermatological Association recommends topical Minoxidil over Capronium Chloride.
User questions credibility of a hair loss "cure" found by a non-expert and warns against wasting money on unproven supplements. Others discuss trying natural extracts and the importance of researching the enzyme 3ADH for potential hairgrowth benefits.
Dr. Muñoz's discovery suggests that targeting potassium channels in fibroblasts could reactivate hairgrowth, offering new treatment possibilities for alopecia. Potential strategies include using minoxidil, diazoxide, and other potassium channel openers, as well as bioelectric devices and direct growth factor applications.
A user shared their 7-month progress on hair regrowth using a regimen of dutasteride, minoxidil, stemoxydine, microneedling, and keto shampoo. They noted significant improvement, particularly in vellus hairgrowth, and discussed the potential addition of RU58841, though they experienced side effects with it previously.
The conversation discusses the synthesis and potential use of JXL069 and PP405 for hair loss treatment, with skepticism about their effectiveness and concerns about safety. Users mention that JXL069 has shown no results in hairgrowth, and there is confusion about its identity and effectiveness compared to PP405.
A user discusses using latanoprost, a costly treatment that may extend the hairgrowth phase and improve hair quality, wondering why it's not more popular. They already use a combination of finasteride and minoxidil and plan to incorporate latanoprost into their routine.
The post and conversation are about a user's successful regrowth of hair using topical minoxidil and rosemary shampoo. Other users discuss the potential limitations of minoxidil and recommend using finasteride to maintain hairgrowth.
The conversation discusses the effectiveness of pumpkin seed oil for hair loss, with mixed opinions on its benefits. Some users mention studies showing potential hairgrowth benefits, while others consider it ineffective.
User shared 9-month progress using Minoxidil 5% (switched to 10% last 3 months) and Finasteride 1mg daily for hairgrowth. Experienced improvement in hair volume, but crown still not fully filled; considering transplant if no further progress.
PP405 and ABS-201 are promising treatments for male pattern baldness. PP405 shows rapid hairgrowth in human trials, while ABS-201 shows significant regrowth in animal studies but is still in early human trials.
Probiotics like L. reuteri ATCC PTA 6475 and B. longum BB536 may improve hairgrowth and density by reducing inflammation and reversing DHT damage. The user is trialing these probiotics personally, ordering them from the U.S. to Canada, and plans to continue if no adverse effects occur.
The GT20029 tincture, a topical androgen receptor degrader, showed significant hairgrowth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.
The user has been using oral minoxidil (3mg) and finasteride (1.2mg) for 3 months. Some users notice hairgrowth, especially at the temples and crown, while others see no difference.
The user added topical finasteride to their regimen of dutasteride and oral minoxidil, noticing a significant reduction in hair shedding after three weeks. They obtained the topical finasteride from a compounding pharmacy with a 0.25% concentration.
A user shared their 5-month progress using a topical treatment with finasteride, minoxidil, and retinoic acid, noting some hairgrowth but also shedding. Another user encouraged them, sharing their own experience of gradual improvement over 12 months and advising patience.
The conversation discusses buying minoxidil, finasteride, and other generic hair loss treatments at subsidized rates in India, and mentions that vitamins and minerals for hairgrowth are also available without a prescription. Some users view the post as an advertisement and note that these products can be purchased from other sources like alldaychemist without a prescription.
The conversation is about creating a higher concentration of the newly FDA-approved hair loss treatment, Clascoterone (Winlevi), through compounding pharmacies and possibly organizing group purchases. Some users are unfamiliar with Winlevi and are asking for an explanation of the drug.
GHK-Cu is discussed for its potential anti-aging and healing properties, with some users considering its effects on hairgrowth. One user mentions using Folligen Spray and topical finasteride, noting improved healing but uncertain hairgrowth results.
Baldness is difficult to cure because current treatments like finasteride, dutasteride, and minoxidil only prevent hair shedding, and new developments are mostly ineffective. Botox shows potential in aiding skin regeneration and hairgrowth, but maintenance therapy with treatments like dutasteride and minoxidil may still be necessary.
Pumpkin seed oil is not a substitute for minoxidil; it acts more like finasteride as a DHT blocker. Minoxidil is necessary for hairgrowth, and combining it with treatments like PRP or saw palmetto may be beneficial.
OP used finasteride 1mg and 2.5mg oral minoxidil since late April, showing hair improvement despite some initial libido issues. Users discussed side effects, costs, and alternative treatments, with OP noting increased facial hair but no significant body hairgrowth.
The conclusion of this conversation is that the user "DuckSeasonCamelSeasn" found that consuming grapefruit juice prior to taking finasteride or dutasteride helped them become a responder to the medications and regain hairgrowth. However, there are warnings about potential risks and interactions with other medications, so caution should be exercised.
Finasteride is prescribed at 1mg because it is FDA-approved and proven effective, despite evidence that 0.2mg may similarly reduce DHT. The 1mg dose is more effective for hairgrowth, and lower doses are less available.