Amplifica starting clinical trials for new hair loss drug. SCUBE3 protein discovered, stimulates hairgrowth, could be alternative to Minoxidil and Finasteride.
The conversation is about finding shampoos that add volume and promote healthy hairgrowth without harsh chemicals. The user from India uses an ayurvedic Aloe Vera shampoo and washes their hair once a week.
Amplifica's new injectable treatment for androgenetic alopecia shows a 15% increase in hair thickness and coarseness in 60 days. The treatment is in early human trials and offers a promising alternative to hormone-related hair loss treatments.
The conversation is a guide on treating hair loss, discussing finasteride and dutasteride to lower DHT, minoxidil for growth, ketoconazole shampoo for scalp health, and dermarolling for regeneration. RU58841 is mentioned as a DHT blocker but not recommended due to safety concerns.
User considers trying AAPE for hair restoration, costing $700 for 6 months. Others discuss its potential effectiveness and mention a study with promising results.
A 21-year-old male experiencing hair thinning started using Minoxidil, which stopped his shedding and led to the growth of vellus hairs on his temples. He is considering whether to add finasteride to his routine, which currently includes Minoxidil, derma rolling, ketoconazole shampoo, vitamin D3, zinc, and a rosemary and fenugreek lotion.
The conversation discusses the potential of long-chain unsaturated fatty acids, like oleic and linoleic acid, as an additional treatment for hair loss, which may inhibit the enzyme responsible for converting testosterone to DHT and promote hairgrowth. Users humorously suggest using oils topically and discuss other hair loss treatments, but the main focus is on the science behind fatty acids and their role in hair health.
Using spirulina and chlorella to boost ferritin and iron levels reduced hair shedding by more than half in a month. The user found these natural supplements more effective than regular iron tablets for hairgrowth.
Microneedling may risk scarring, potentially complicating future hair transplants. Alternatives like tretinoin with minoxidil are suggested for better hairgrowth.
Finasteride and oral minoxidil significantly improved hair texture and thickness over 8 months. The user also experienced increased hairgrowth on the beard and eyebrows.
A user's father, mostly bald for 20 years, is regrowing hair using a serum called "Skrzypovita Serum Pro" without minoxidil. The user is curious about which ingredients might be causing hairgrowth.
The user has been taking finasteride 1mg/day since 2021 and recently added oral minoxidil 2mg/day for 40 days. They are questioning if the observed hairgrowth is due to minoxidil.
The conversation discusses the possibility of transplanting leg and arm hair to the scalp for hair loss treatment. Minoxidil is mentioned as a potential aid for hairgrowth, but concerns about the effectiveness and appearance of body hair on the head are raised.
Switching from finasteride and topical minoxidil to oral minoxidil and dutasteride worsened hair condition, leading to frustration and heart issues, prompting a return to topical treatments and the addition of tretinoin. Patience and consistency are advised, as these treatments can take years to show results, and abrupt changes may cause shedding.
The user has been using finasteride, nizoral, microneedling, and recently added 3% peppermint oil to their hair loss treatment, experiencing regrowth similar to minoxidil. They suggest peppermint oil as a potentially effective, low-cost alternative or addition to minoxidil, with the added benefit of a pleasant smell and ease of use.
Caffeine may promote hairgrowth and potentially inhibit 5-α-reductase activity in hair follicles, but its effectiveness and systemic impact remain unclear. Users discuss using topical caffeine solutions, with some experiencing no side effects compared to finasteride.
PP405 shows some hairgrowth after 4 weeks, but results are debated and expectations should be tempered. Some users compare it to minoxidil or finasteride, questioning its effectiveness and commercialization timeline.
Estrogen injections significantly improved hairgrowth, particularly on the crown, after stopping finasteride. Monotherapy with estrogen led to hairline improvement, but also caused sterility and potential feminization effects.
Clascoterone has shown promising results in increasing hair density without systemic side effects, potentially offering benefits similar to finasteride. There is skepticism due to the lack of published photos despite the market interest.
Topical diazoxide may be a promisinghair regrowth treatment, especially for those who don't respond to minoxidil, as it activates potassium channels without needing sulfation. It appears safe for topical use, avoiding systemic effects seen in oral use.
The user reports promisinghair regrowth without using finasteride, focusing instead on microneedling, dermarolling, minoxidil, tretinoin, scalp massages, and red light therapy. They emphasize consistency and a healthier, side-effect-free approach.
Follica's preferred microneedling protocol for hairgrowth, which includes needle depth, frequency and movement parameters as well as the use of topical treatments such as minoxidil and finasteride.
Breezula shows promise in stabilizing hair loss and potentially promoting regrowth at the one-year mark, offering hope for those who can't tolerate 5AR inhibitors. Its local targeting of androgen receptors could be a significant advancement if it avoids systemic side effects.
PP405 is a promisinghair loss treatment that may outperform minoxidil and finasteride by reviving dormant follicles and promoting significant regrowth. Results from ongoing trials are awaited, with a potential market release between 2028-2030.
BPC-157 may promote hairgrowth by increasing angiogenesis, similar to how Minoxidil works, though no direct research confirms this yet. Users report combining BPC-157 with Minoxidil and finasteride for better results, but concerns about long-term safety exist.
Minoxidil helps hairgrowth on both scalp and face, but stopping it leads to hair loss on the scalp, not the face. The user questions why scalp hair can't be maintained with finasteride or androgen blockers after stopping minoxidil, despite these treatments reducing DHT damage.
Red light therapy has shown promising results in hair regrowth for the user, who avoids minoxidil and finasteride due to side effects. The user follows a healthy lifestyle with diet, exercise, and sauna use, and will continue monitoring the therapy's effectiveness.
The user shared impressive hairgrowth results after 100 days using finasteride, minoxidil, biotin, and saw palmetto, and plans to get a hair transplant. The conversation includes suggestions for additional treatments like ketoconazole and derma stamping, and discussions about potential side effects of finasteride.
The user reported significant hairgrowth after 8 months using a topical solution of 0.25% Finasteride and 8% Minoxidil, with no side effects. They also performed micro-needling and took multivitamins.
Microneedling can promote hairgrowth, but there is uncertainty about the best practices, including needle length, device, and session frequency. Users discuss using needle lengths between 0.5mm and 1.5mm, with some experiencing pinpoint bleeding, and emphasize the need for more reliable resources and guidelines.