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      community PYRILUTAMIDE PHASE 3 RESULTS : No statistical significance

      in Research/Science  126 upvotes 2 years ago
      The phase 3 trial results for Pyrilutamide showed no significant difference from the control treatment in increasing hair count, leading to the company halting its development. Users discussed their disappointment and skepticism about hair loss treatments, with some mentioning other treatments like Minoxidil, Finasteride, and RU58841.

      community New Treatments, and a Huge Group Buy with Lots of Research

      in Research/Science  109 upvotes 2 years ago
      A user is organizing a group buy for various compounds aimed at reversing hair loss and gray hair, and improving brain health and fat loss. The user has developed a treatment plan based on extensive research and is inviting others to participate, with the option to choose only the compounds they need.

      community 20M NW6 diffuse —> NW1 Fin/Dut

      in Progress Pictures  72 upvotes 1 year ago
      A user shared progress pictures showing improvement from NW6 diffuse to NW1 after 5 months of finasteride and 2 months of dutasteride. Another user asked if these treatments affected beard or body hair thickness.

      community Rob Holding hair transplant looks unbelievable

      in Transplants  600 upvotes 3 years ago
      Rob Holding's hair transplant, which looks great despite the edited image of it; many respondents discussed their opinions on the hairstyle, while others suggested treatment options like Minoxidil and Finasteride.

      community Summary of future treatments from 2020

      in Chat  54 upvotes 8 months ago
      Hair loss treatments include finasteride, minoxidil, microneedling, dutasteride, CB-03-01, RU-58841, and experimental options like KY-19382 and stem cell therapy. Some treatments are considered ineffective or risky, such as ketoconazole, PRP, and low-level laser therapy.

      community Should i start meds or see another dermatologist?

      in Is this regrowth?  4 upvotes 2 months ago
      The user is experiencing unexpected hair thinning and is considering starting finasteride and minoxidil after a dermatologist's brief assessment. They are hesitant and seeking opinions, with some users suggesting finasteride alone might be sufficient for mild hair loss.

      community 1 year vs 2 years on 1mg Finasteride [29M]

      in Progress Pictures  16 upvotes 2 months ago
      The user has been on 1mg finasteride daily for two years, experiencing initial shedding and some hairline recession, with limited regrowth. Suggestions include using oral minoxidil, switching to dutasteride, or considering a hair transplant for better results.

      community 19f is my hair loss due to deficiencies?

      in Female  4 upvotes 4 months ago
      The conversation is about a 19-year-old female experiencing hair loss, potentially due to deficiencies in iron, ferritin, and vitamin D. She is considering iron and vitamin D supplementation and exploring dietary changes, while also planning to consult a dermatologist when possible.

      community My Theory Of Androgenic Alopecia

      in Research/Science  18 upvotes 4 months ago
      Hair loss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.

      community Why Is No One Talking About Chromosome 20?

      in Chat  32 upvotes 6 months ago
      Some hair loss may be linked to chromosome 20, which isn't affected by DHT blockers like finasteride. Treatments like minoxidil, microneedling, and genetic testing are suggested, but their effectiveness for this type of hair loss is uncertain.

      community Yes your lifestyle and diet has its role in hair loss.

      in Chat  296 upvotes 7 months ago
      Diet and lifestyle changes can reduce hair shedding but won't regrow hair lost to genetic male pattern baldness. Treatments like finasteride and dutasteride are necessary for significant hair regrowth.

      community Sugar and Hair loss connections

      in Research/Science  41 upvotes 10 months ago
      High sugar diets may worsen hair loss by increasing 5α-reductase activity and androgen levels, especially in women with PCOS. A low sugar diet might reduce scalp DHT levels, similar to finasteride, but genetics also significantly influence hair loss.

      community Me on 5 milligrams of Finasteride, off label oral Min, a $3000 red light therapy cap, experimental Russian drugs, and three Turkish hair transplants watching a 60 year old homeless man with a perfect hairline smoke crack

      in Satire  2726 upvotes 1 year ago
      The conversation humorously discusses the unfairness of hair loss, highlighting various treatments like finasteride, minoxidil, red light therapy, and experimental drugs, while contrasting with people who have great hair despite unhealthy lifestyles. The original poster mentions experiencing side effects from switching to oral finasteride.

      community don't deny the truth you know in your heart of hearts

      in Satire  1981 upvotes 1 year ago
      Hair loss treatments like finasteride, minoxidil, and ketoconazole shampoo are discussed humorously, with skepticism about future cures. Users express frustration over the lack of a permanent solution and joke about investing in stocks or using time travel to solve baldness.

      community 5 months topical spiro + minox + micro

      in Progress Pictures  7 upvotes 1 year ago
      A 35-year-old male uses topical minoxidil, spironolactone, and microneedling for hair loss, with spironolactone prescribed based on a DNA test indicating poor response to finasteride and dutasteride. Despite concerns about the test's validity and spironolactone's side effects, he reports stable or improved hair condition and no low testosterone symptoms.

      community Breezula phase 3 results said to be released next month

      in Product  28 upvotes 1 year ago
      Breezula's phase 3 results are expected soon, with discussions on the effectiveness of androgen receptor antagonists like spironolactone and the potential of GT20029. Users express skepticism about new treatments and discuss the complexities of male pattern baldness, often relying on finasteride despite its side effects.

      community Why does finasteride stop working?

      in Finasteride/Dutasteride  26 upvotes 1 year ago
      Finasteride may seem less effective over time due to increased DHT sensitivity or aging, but it still suppresses DHT. Switching to dutasteride offers stronger DHT suppression but may increase estrogen levels.

      community A hill on which I will die: The DHT itch absolutely exists

      in Research/Science  210 upvotes 1 year ago
      The DHT itch is linked to hair loss and persists despite finasteride use; switching to dutasteride helped alleviate the itch and promoted regrowth. Some users suggest seborrheic dermatitis as a cause and recommend treatments like medicated shampoos, vitamin D, and minoxidil.

      community Let's talk about natural options and last resorts.

      in Chat  7 upvotes 1 year ago
      The user discusses their long struggle with hair loss, considering various treatments like hair transplants, hair systems, and natural methods such as micro-needling, vitamin supplements, and a healthy lifestyle. They express concerns about side effects from drugs like finasteride and ultimately lean towards using a hair system for better appearance and confidence.

      community How to know if shedding is from tren or minoxidil?

      in Minoxidil  5 upvotes 2 years ago
      The user started using trenbolone and minoxidil simultaneously and experienced increased hair shedding, unsure which is causing it. Replies suggest both drugs could cause hair loss, with one advising to stop trenbolone to protect hair and another indicating minoxidil is unlikely the cause due to the timing.

      community Why is it barely impossible to find balding South Korean men

      in Research/Science  251 upvotes 2 years ago
      The post discusses the rarity of baldness among South Korean men. Users suggest this could be due to early treatment, high beauty standards, accessibility of healthcare, and genetics. Treatments like finasteride and dutasteride are commonly used, and hair transplants are also popular.

      community NW5 at 19. How many grafts do I need?

      in Transplants  142 upvotes 2 years ago
      A 19-year-old with rapid hair loss since 16 is considering a hair transplant but refuses to take finasteride or any 5α-Reductase inhibitors. They are currently using minoxidil, tretinoin, and microneedling with a Derminator 2, and only want hair until age 27.