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      community Dutasteride only might be the best ROI

      in Finasteride/Dutasteride  176 upvotes 2 months ago
      Switching from finasteride to dutasteride can improve hair regrowth with fewer side effects for some users. Concerns about shedding, lack of improvement, and the long-term safety of oral minoxidil remain.

      community 3,5 months of only topical minoxidil

      in Minoxidil  778 upvotes 4 months ago
      A 24-year-old reported new hair growth on temples after 3.5 months of using topical minoxidil without shedding. They plan to add finasteride to maintain progress, as minoxidil alone may not be enough long-term.

      community What’s your views on clascoterone 5% topical solution by cosmo

      in Research/Science  23 upvotes 4 months ago
      Clascoterone 5% topical solution shows promise for treating male-pattern hair loss by blocking DHT at the follicle without systemic absorption, potentially offering fewer side effects than oral treatments like finasteride. While results are promising, long-term safety and effectiveness need further study, and it may serve as a starting point for developing more effective treatments.

      community Topical Dutasteride usage plan + build up prevention

      in Finasteride/Dutasteride  8 upvotes 5 months ago
      The conversation discusses using a 0.03% topical Dutasteride solution for hair loss, as it may be more effective than Finasteride with fewer systemic side effects. OP plans to apply it daily for 100 days, then reduce frequency, due to past negative cognitive effects from oral treatments.

      community Why you may be taking Dutasteride wrong

      in Finasteride/Dutasteride  63 upvotes 6 months ago
      Dutasteride is more effective than finasteride for hair loss, with optimal dosing at 0.5mg once or twice a week to minimize side effects. Topical application may further reduce side effects while effectively lowering scalp DHT.

      community Creatine is the opposite of minoxidil !

      in Research/Science  318 upvotes 6 months ago
      Creatine may counteract minoxidil's hair growth effects by closing potassium ATP channels, potentially leading to hair loss in predisposed individuals. Despite anecdotal reports, there is no conclusive evidence linking creatine to hair loss.

      community Quote from Pelage (PP-405) Spokesperson...

      in Research/Science  122 upvotes 6 months ago
      Pelage is developing a topical hair follicle stem cell therapy, PP405, for non-scarring alopecias like androgenetic alopecia, with Phase III trials planned and a potential market launch by 2027. The treatment may not require continuous use after initial regrowth.

      community Story time! The Great Unbalding (PP405)

      in Research/Science  233 upvotes 6 months ago
      PP405 is a promising new hair loss treatment that may reactivate dormant hair follicles without side effects. It could surpass traditional treatments like minoxidil and finasteride if successful in further trials.

      community 27M - look 2 months on Oral 3-in-1 - 1.1mg fin+5g min+ 1mg biotin

      in Progress Pictures  1398 upvotes 7 months ago
      A 27-year-old male experienced significant hair regrowth in two months using a daily oral 3-in-1 pill containing 1.1mg finasteride, 5mg minoxidil, and 1mg biotin from LockLab, with no side effects reported. The user also uses a derma-stamp twice a week to promote blood flow and stimulate growth.

      community Steam cells treatment research is promising

      in Research/Science  48 upvotes 7 months ago
      Stem cell treatment research shows promise in reversing hair loss in mice, but it's likely 10 years away and expensive. Current recommended treatments include minoxidil, finasteride, and hair transplants.

      community Why is scalp DHT suppression lower than systemic?

      in Finasteride/Dutasteride  11 upvotes 8 months ago
      Dutasteride reduces DHT more effectively in hair follicles than finasteride, but some individuals still experience hair loss despite treatment. Combining oral and topical finasteride may improve results, and some users experiment with topical dutasteride despite uncertainties about its absorption.

      community Is 20 too young for Dut (or fin)?

      in Finasteride/Dutasteride  18 upvotes 9 months ago
      A 20-year-old is considering starting dutasteride or finasteride for hair loss, with concerns about potential side effects and development. Users shared experiences with both treatments, noting that finasteride is often the first step, while dutasteride may be more effective for some, and emphasized consulting a healthcare provider.

      community How I'm becoming a saint by using Finasteride for 9 month

      in Satire  1126 upvotes 9 months ago
      Finasteride use resulted in increased hair growth but reduced libido for some, leading users to consider topical versions to lessen side effects. Opinions varied on the trade-off between hair benefits and sexual side effects.

      community Summary of Procapil video by Haircafe

      in Minoxidil  2 upvotes 9 months ago
      Procapil is marketed as a natural hair loss treatment but lacks strong evidence and is industry-biased. Minoxidil and Finasteride are the only FDA-approved treatments for androgenetic alopecia.

      community I think this is my stop, gentlepeople. So long and thanks for all the data 👋

      in Transgender  2262 upvotes 9 months ago
      A user shared their successful experience with hair regrowth and transitioning from male to female using minoxidil, finasteride, Nutrafol, microneedling, and hormone replacement therapy (HRT). They expressed gratitude for the results and encouraged others to explore treatments that align with their personal goals.

      community What do you think about this study?

      in Product  112 upvotes 9 months ago
      The conversation discusses skepticism about new hair loss treatments, with many users expressing doubt about the effectiveness and availability of future solutions. Current treatments like minoxidil, finasteride, and hair transplants are mentioned as reliable options.

      community Petition: Make PP405 available tomorrow instead of 2030

      in Satire  329 upvotes 10 months ago
      PP405, a promising hair loss treatment, is expected to be available by 2027, with faster trials due to its topical nature. Users are eager for its release, comparing it to existing treatments like minoxidil and finasteride, but remain cautious about its long-term effectiveness.

      community On the big 6 but very slow , needs acceleration

      in Is this regrowth?  30 upvotes 10 months ago
      The user is using a hair regrowth protocol including dutasteride, topical and oral minoxidil, dermarolling, ketoconazole shampoo, and tretinoin, but is experiencing slow progress and seeks advice for faster regrowth. Suggestions include quitting smoking, adjusting the regimen, and considering additional treatments like topical finasteride or RU58841.

      community Thoughts on new drug PP405? Already reached phase 2

      in Research/Science  28 upvotes 10 months ago
      PP405 is a new drug in Phase 2 trials for hair loss, generating cautious optimism among users. Some users are currently using finasteride and experiencing side effects, while others are skeptical about unapproved products being sold.

      community Efficacy and Systemic DHT Suppression of Topical Finasteride vs Dutasteride

      in General  122 upvotes 1 year ago
      Topical dutasteride may have limited absorption due to its higher molecular mass compared to finasteride, potentially affecting its efficacy in suppressing DHT locally. Microneedling might enhance dutasteride absorption, possibly offering stronger local DHT suppression with fewer systemic effects.

      community Dutasteride just FEELS better than finasteride

      in Finasteride/Dutasteride  172 upvotes 1 year ago
      Dutasteride is favored over finasteride by some for better hair loss reversal, improved skin, and fewer side effects, though individual responses vary. It may also help with dandruff and eczema but has a slightly higher risk of gynecomastia.

      community How far are we from a treatment better than finasteride?

      in Treatment  129 upvotes 1 year ago
      Dutasteride is more effective than finasteride for hair loss as it blocks more of the enzyme causing hair loss. New treatments like stem cell therapies and alternatives to minoxidil are being explored, but major advancements are still years away.