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      community Can this be salvaged with a second transplant?

      in Transplants  22 upvotes 1 month ago
      The user is considering a second hair transplant after previous treatments with finasteride and minoxidil failed to stop hair loss. Suggestions include trying dutasteride, oral minoxidil, scalp micropigmentation, or shaving the head.

      community 1.5 Year Hair Restoration Journey - Stem Cells, PRP, Minoxidil, Topical Finasteride

      in Progress Pictures  26 upvotes 2 years ago
      A user shared their 1.5-year hair restoration journey, successfully using mesenchymal stem cell therapy, Platelet Rich Plasma (PRP) injections, and a topical compound of finasteride and minoxidil, avoiding a hair transplant and oral finasteride. They experienced significant hair regrowth, particularly crediting the stem cell therapy for quick initial results.
      Smp density or 2nd hair transplant?

      community Smp density or 2nd hair transplant?

      in Hair Transplants  103 upvotes 11 months ago
      The user is considering a second hair transplant or scalp micropigmentation to address thinning in the crown area and hide scars from a previous transplant. They have been using finasteride and minoxidil for three years but are concerned about the appearance of their donor area and the effectiveness of scalp micropigmentation.

      community HLT Megathread on HMI-115 (key takeaways in comments)

      in Research/Science  39 upvotes 3 years ago
      HMI-115, a newly discovered hair loss treatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.

      community Good news for stem cells hair therapies - US federal judge: using patients' stem cells does NOT fall under FDA jurisdiction

      in Research/Science  26 upvotes 3 years ago
      A US federal judge ruled that using patients' stem cells for medical treatments is not under FDA jurisdiction, potentially speeding up development of stem cell-based hair loss therapies. Some users are optimistic about increased research and development, while others express skepticism about the ruling's impact on safety and efficacy standards.

      community Is my friend lying about getting a transplant?

      in Transplants 5 months ago
      A person suspects their friend had a hair transplant instead of stem-cell injections due to a noticeably straight hairline. The discussion includes opinions on hair transplants, societal perceptions, and suggestions like using finasteride to maintain hair.

      community Does DHT Cause Complete Baldness?

      in Research/Science  5 upvotes 9 months ago
      Hair cloning technology is advancing, with clinical trials for improved methods expected by 2028 and 2029, potentially offering a solution for hair loss if donor follicles remain. Organtech's expansion into other biotech areas may secure funding, but the effectiveness of cloning depends on the availability of androgen-resistant donor follicles.

      community How many grafts for second HT? Thinking of Turkey.

      in Treatment  1 upvotes 5 months ago
      The user had a hair transplant in 2021 with 1600 grafts and is currently using finasteride, minoxidil, biotin, and collagen. They are considering another transplant in Turkey to address a bald spot and improve coverage in the front and middle.

      community Is PP405 actually different, or does it fall into the same pattern as previous treatments?

      in Research/Science 3 months ago
      PP405 is being discussed as a potential new approach to hair loss by targeting follicle stem cells, suggesting a different mechanism from existing treatments like finasteride and minoxidil. However, there is skepticism about whether it will lead to meaningful long-term outcomes or follow the pattern of previous treatments that showed promise but lacked consistent results.

      community A Short Recap on PP405 and AAD 2026

      in Update 2 months ago
      PP405 is a promising experimental topical treatment for alopecia that reactivates dormant hair follicles by targeting cellular energy, with large-scale trials planned for 2026. While it shows potential, it cannot regenerate permanently destroyed follicles, making hair transplants the only guaranteed solution for advanced baldness currently.

      community Is it possible to transplant all of my hair to one spot on my head?

      in Satire  34 upvotes 2 years ago
      A user humorously discusses wanting to transplant all their hair into one dense circle on their scalp, leaving the rest of their head bald. Replies include a joke about performing the procedure and a story about someone using their hair to fight crime.

      community how much hair can you transplant into your scalp

      in Chat  7 upvotes 1 year ago
      A 20-year-old experiencing hair loss since age 16 is using finasteride and minoxidil and is considering future hair transplants. Discussions include the potential for multiple transplants, the use of body hair for coverage, and the importance of treatments like dutasteride and scalp micropigmentation for maintaining hair density.

      community Not responding to any treatment - is HT the only way?

      in Progress Pictures  4 upvotes 5 months ago
      The user has tried various treatments for hair loss, including finasteride, dutasteride, and oral minoxidil, but is considering a hair transplant due to insufficient progress. Some users suggest that the treatments have at least stabilized hair loss, and recommend consulting clinics for a potential hair transplant while continuing medication.
      PP405 Identity Research

      community PP405 Identity Research

      in Research  292 upvotes 10 months ago
      PP405 is a potential hair loss treatment that inhibits mitochondrial pyruvate carriers, increasing lactate dehydrogenase activity and stimulating hair follicle stem cells. In a phase 1 trial, 31% of participants showed over 20% hair density increase with PP405 treatment.

      community 5 years – Fin, Min, Microneedle and then HT

      in Transplants  223 upvotes 3 years ago
      A user's experience of using Fin, Min and Microneedle treatments to help thicken their hair before undergoing a Hair Transplant (HT) procedure. The conversation also includes discussion about the results post-HT, including pictures.

      community What do you guys think of stem cell hai restoration?

      in Chat  9 upvotes 5 months ago
      Stem cell hair restoration lacks scientific evidence and is often considered a scam. Effective hair loss treatments include hair transplants, Minoxidil, and Finasteride, but stem cell treatments are not proven.

      community Hyperbaric Oxygen Therapy (HBOT)

      in Research/Science  8 upvotes 4 years ago
      Hyperbaric Oxygen Therapy (HBOT) is discussed as a potential treatment for androgenic alopecia due to its ability to reverse hypoxia and promote angiogenesis. The conversation explores its potential benefits for hair loss, though no studies have been conducted on this application yet.