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3aHSD enzyme's role in hair loss and a crowdfund for research. Goal: explore new treatments, study RU58841, and develop natural topical product.

A user noticed wrinkling under one eye, possibly due to Minoxidil use. They seek advice on preventing or fixing this issue.

A user's 6 month hairline results from using dutasteride and microneedling, which resulted in successful regrowth of their thinning temples. Other users commented with similar experiences that were also achieved through the use of finasteride, dutasteride and minoxidil.

New potential hair loss treatment uses molecules from hairy moles to stimulate follicle growth. Topical solution requires less frequent application, like Botox injections a few times per year.

The conversation discusses a natural approach to hair loss treatment, including using natural shampoo, daily scalp massages, derma rolling, and dietary changes, with the goal of improving hair health. Some users express skepticism about natural methods, advocating for finasteride or minoxidil, while others share positive experiences with natural treatments like essential oils and derma rolling.

User RG737 considers hair system as last resort for hair loss, as finasteride and alternative remedies didn't work. Jeff-92 shares positive experience with hair system, suggesting to try it and push through initial doubts.

The conversation discusses using finasteride for hair loss, with iron supplements helping to slow shedding. The user emphasizes that shedding doesn't necessarily mean permanent hair loss.

User phoenixblue asked about hair fiber products like Toppik and if they cause hair loss by clogging pores. Replies suggested that Toppik is safe, but effectiveness varies; some users experienced no hair loss, while others had issues with color or sweating.

The conversation discusses how applying topical tretinoin for 5 days can convert 43% of individuals who initially do not respond to minoxidil into responders, enhancing the effect of minoxidil on hair growth. Specific treatments mentioned are minoxidil and tretinoin.

A user shared their 2-month results using Minoxidil 5%, dermarolling, ketoconazole shampoo, and castor oil for hair loss. They stopped using finasteride due to side effects.

The conversation discusses the completion of a Phase II trial recruitment for Breezula (CB-03-01), a potential treatment for androgenic alopecia. Specific treatments mentioned include Minoxidil, Finasteride, and RU58841.

Setipiprant and Fevipiprant are questioned for their effectiveness in hair maintenance, with skepticism due to lack of convincing results beyond vellus hair growth. The user is satisfied with Minoxidil and Finasteride but is curious about the potential of DP2 inhibitors.

A dermatologist recommended a new supplement containing annurca apple, which reportedly doubles hair density and increases keratin after 60 days, to be used with finasteride. Some users are skeptical, considering it potentially ineffective or a marketing ploy, while others are open to trying it if it proves effective and affordable.

Microneedling may risk scarring, potentially complicating future hair transplants. Alternatives like tretinoin with minoxidil are suggested for better hair growth.

Rob English, known for promoting scalp massages for hair regrowth, now sells his own brand of finasteride and minoxidil. Opinions are mixed, with some calling him a charlatan and others acknowledging his shift towards scientifically-backed treatments.

The conversation discusses using a 0.03% topical Dutasteride solution for hair loss, as it may be more effective than Finasteride with fewer systemic side effects. OP plans to apply it daily for 100 days, then reduce frequency, due to past negative cognitive effects from oral treatments.

This user has had success with Minoxidil foam, achieving significant hair growth in three months without using finasteride or derma rolling. They are considering incorporating a DHT reducing strategy such as finasteride in the future.

User redh0t12 suggests using a derma pen for hair regrowth, as it helped them after using finasteride and minoxidil. Others discuss their experiences with various treatments, including derma rolling, oral and topical minoxidil, and finasteride, with mixed results.

The conversation discusses hair loss treatments, focusing on insulin resistance, microneedling with topical melatonin, and stress reduction. Users express skepticism about the advice, preferring proven treatments like minoxidil and finasteride, while some mention alternative methods like dermal incisions and verteporfin for reducing fibrosis.

The user restored their hair using 5% minoxidil liquid, a 5 mg minoxidil pill, and dutasteride, experiencing no side effects. Others shared mixed experiences with dutasteride and finasteride, noting side effects like reduced libido and erection issues.

The user is experiencing hair loss despite using estradiol, bicalutamide, dutasteride, and topical minoxidil. They stopped minoxidil temporarily, which worsened their condition, and are considering oral minoxidil but are concerned about side effects and cost.

A permanent hair loss solution could involve reprogramming hair follicles to resist DHT using mRNA and siRNA. However, high costs, safety concerns, and the pharmaceutical industry's preference for ongoing treatments over one-time cures are major obstacles, with finasteride and minoxidil remaining standard treatments.

The user shared their 3-month progress using 5% topical minoxidil and microneedling with a 1mm dermaroller, noting significant hair growth without using finasteride. They applied minoxidil twice daily and used the dermaroller three times a week, experiencing a short shedding phase after 2-3 weeks.

Adding an LLLT laser cap to a routine of finasteride, minoxidil, and ketoconazole shampoo significantly reduced hair shedding from 200+ hairs a day to around 80, improving scalp health. The user attributes the laser cap as the key factor in stabilizing hair loss after two years of using other treatments.

A user in their 40s is using finasteride every other day and ketoconazole shampoo for hair loss, considering adding topical minoxidil for further regrowth, including on eyebrows. They are advised to continue with the current regimen for a few more months before reassessing and to be cautious with minoxidil due to its application challenges and potential risks to pets.

The user achieved significant hair regrowth using oral finasteride for 2 years, then switched to topical minoxidil with rosemary oil and biotin oil. They reported no side effects and found topical minoxidil more effective than oral minoxidil.

Dutasteride is considered a powerful treatment for hair loss, potentially effective for decades, but its success depends on individual genetics and response. Combining Dutasteride with other treatments like Minoxidil, Finasteride, and RU58841 may enhance results, but outcomes vary.

The user shared their positive experience with hair regrowth using finasteride, oral and topical minoxidil, and keto shampoo, noting gradual improvement and no side effects. They emphasized the importance of starting treatment early and maintaining consistency and patience.

A user experienced side effects from finasteride and switched to using GHK-Cu for hairline improvement, noticing some positive changes after three months. They used a 2mg daily dose via subcutaneous injections and reported increased hair density and baby hairs, though results were not dramatic.

Deoxyribose sugar gel may stimulate hair regrowth similarly to minoxidil by enhancing blood supply and follicle activity. Human trials are necessary, and current products have mixed results.