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      community PP405 is NOT gray market jxl069

      in Technology  26 upvotes 4 months ago
      PP405 is a safer alternative to JXL069 for hair loss treatment because it penetrates the skin effectively and degrades in the blood, avoiding systemic toxicity. JXL069, when forced into the body, can cause dangerous side effects like lactic acidosis due to its inability to degrade safely.

      community RU58841 is the only thing that worked for me, a DUPA sufferer

      in Treatment  1 upvotes 11 months ago
      RU58841 was the only treatment that slowed hair loss and reduced irritation for a DUPA sufferer after trying finasteride, minoxidil, and dutasteride with no success. The user continues using 6mg oral minoxidil, 0.5mg dutasteride, and an 8% RU58841 solution.

      community Dutasteride and Haircafe save lives

      in Progress Pictures  202 upvotes 6 months ago
      The user experienced significant hair improvement after 15 months of treatment, using finasteride initially, then switching to dutasteride, and recently adding topical minoxidil. They credit their progress to dutasteride and support from Haircafe, a YouTuber.

      community (17M) Hair loss and Cystic Acnes / Dutasteride

      in Finasteride  109 upvotes 6 months ago
      A 17-year-old is using Finasteride and Minoxidil for hair loss, experiencing hair shedding and cystic acne. They are considering Dutasteride for acne but are concerned about potential side effects on genital development.

      community Fevipiprant 2019!

       15 upvotes 9 years ago
      The conversation discusses Fevipiprant, an asthma drug that may block CRTH2 and potentially stop male pattern baldness (MPB) without inhibiting DHT. It also mentions the use of finasteride and dutasteride for hair loss.

      community Here to share my happiness bros! DHT blockers are magic

      in Progress Pictures  115 upvotes 10 months ago
      The user experienced significant hair regrowth using finasteride and dutasteride, with noticeable results after switching to dutasteride. Minoxidil was deemed unnecessary due to the restoration of the hairline and lack of hair follicles in bald spots.

      community My experience and a discourse on “DUPA”

      in Chat  46 upvotes 3 years ago
      How diffuse unpatterned alopecia (DUPA) is not an invitation to self-diagnose oneself with aggressive AGA and that seeking a specialized dermatologist may help people experiencing hair loss. Treatment options discussed include topical clobetasol propionate, oral minoxidil, and discontinuing finasteride.

      community Best Treatment In The Pipeline?

      in Chat  15 upvotes 1 year ago
      New treatments for AGA are emerging, including pyrilutumide, gt0029, scube3, kx-826, and pp405. Verteporfin is mentioned as a promising option.

      community M28 104 days on dut+min and cafune shampoo

      in Progress Pictures  156 upvotes 2 months ago
      A 28-year-old has been using oral dutasteride 0.5 mg, topical minoxidil 5%, and Cafune shampoo for 104 days with positive results and is considering adding microneedling. No side effects from dutasteride have been reported.

      community 7 month progress check-in (fin/min)

      in Is this regrowth?  9 upvotes 9 months ago
      A 19-year-old is using minoxidil, finasteride, tretinoin, caffeine, and oils for hair regrowth, with positive results and no side effects. They are considering increasing finasteride dosage and possibly switching to dutasteride in the future.

      community Dut for 8 months, getting crushed honestly

      in Update  43 upvotes 1 year ago
      The user has been using dutasteride, oral minoxidil, and vitamin D for 8 months with no improvement in hair loss. They are considering trying RU58841 or a hair transplant due to the ineffectiveness of current treatments.

      community 7 Months Minoxidil & Finasteride

      in Progress Pictures  1 upvotes 1 year ago
      The user shared progress on hair regrowth after 7 months using Minoxidil 5% twice daily, Finasteride 1mg once daily, vitamin D3, and Neurobion injections. They encouraged others to persist with their treatments, noting visible improvements and expecting further gains.

      community 7 month progress. From a slap head to a forehead. (32M)

      in Progress Pictures  53 upvotes 5 months ago
      A 32-year-old male shares his 7-month hair regrowth progress using 1 mg finasteride daily, 5% minoxidil twice daily, dermarolling every four days, 1.5% ketoconazole shampoo every three days, and zinc and vitamin D supplements initially. He applies minoxidil primarily to his temples and hairline, avoiding the crown, and reports significant improvement in diffusive thinning.

      community A Short Recap on PP405 and AAD 2026

      in Update 2 months ago
      PP405 is a promising experimental topical treatment for alopecia that reactivates dormant hair follicles by targeting cellular energy, with large-scale trials planned for 2026. While it shows potential, it cannot regenerate permanently destroyed follicles, making hair transplants the only guaranteed solution for advanced baldness currently.

      community Finally regrowth on the crown of my head after five years and switch to Dut!

      in Progress Pictures  25 upvotes 2 years ago
      After five years of no progress with hair regrowth using oral finasteride and topical minoxidil, a person switched to a combination of topical dutasteride, minoxidil, tretinoin, ketoconazole, and hydrocortisone in November 2023 and finally saw results. They had previously experienced side effects like gynecomastia from finasteride.

      community 5ARI (dutasteride) Associated with Adverse Metabolic Effects

       22 upvotes 8 years ago
      Dutasteride is associated with increased blood glucose, HbA1c, LDL cholesterol, and liver enzyme activity, potentially leading to diabetes, NAFLD, and liver metabolism changes. The conversation highlights concerns about these adverse effects and calls for more studies, including on finasteride.