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      community Debunking Androgenetic Theory (Hair Transplants)

      in Research/Science  25 upvotes 2 years ago
      The post discusses a theory that hair regrowth after transplant is due to the angiogenesis process (new blood vessels forming), not because the transplanted hair is unaffected by DHT. The responses highlight the established belief in 'donor dominance' (the importance of the hair's origin in transplantation) and skepticism about the new theory.

      community (MTF 35) Results of 18 Months of HRT

      in Transgender  783 upvotes 7 months ago
      A transgender woman experienced significant hair regrowth after 18 months of hormone replacement therapy (HRT) with estrogen and bicalutamide. The discussion notes HRT's effectiveness for hair regrowth but warns against its use for cisgender men due to feminizing effects.

      community hairloss in my 20s has ruined my life.

      in Research/Science  373 upvotes 1 year ago
      A person in their 20s is struggling with hair loss, using treatments like minoxidil and finasteride. Suggestions include self-improvement, therapy, hair transplants, and focusing on acceptance and confidence.

      community Going off Minoxidil then using oils

      in Minoxidil 2 years ago
      The conversation discusses stopping oral minoxidil after 2 years and using rosemary/peppermint oil instead, with the concern of losing hair gains. Replies suggest that switching to oils will result in losing all the hair gains achieved with minoxidil.

      community Personal experiment: tretinoin and diffuse thinning

      in Treatment  9 upvotes 3 years ago
      User experienced hair growth with finasteride and minoxidil, but after using tretinoin, faced aggressive thinning and hair loss. They plan to stop tretinoin for two months to see if the problem improves.

      community Libido on Finasteride

       4 upvotes 11 years ago
      The conversation discusses the effects of finasteride on libido, with the original poster experiencing a significant decrease in sexual desire after starting the medication. Other users share similar experiences and suggest potential remedies, including Vitamin E supplementation and lifestyle changes like avoiding pornography.

      community Male pattern baldness is not cosmetic.

      in Chat  223 upvotes 8 months ago
      Male pattern baldness is linked to health risks and should be treated medically. Finasteride is effective and should be insurance-covered.

      community My Delusional Hope - This page becomes irrelevant in 2030s

      in Chat  55 upvotes 9 months ago
      People are hopeful for a permanent hair loss solution by the 2030s, considering options like hair cloning and treatments like pp405. Synthetic hair transplants have been attempted but are not effective long-term.

      community What product does David Dobrik use

      in Chat  336 upvotes 11 months ago
      David Dobrik uses Minoxidil and possibly Finasteride for hair loss but applies them incorrectly. Users suggest he consider surgery due to his financial capability.

      community If PP405 goes systemic this would be quite catastrophic

      in Research/Science  4 upvotes 1 year ago
      Concerns about the potential systemic effects and safety of PP405 for hair loss, with discussions on its comparison to existing treatments like finasteride and minoxidil. Users express skepticism about untested research chemicals and emphasize the importance of clinical trials to ensure safety and efficacy.

      community If dutesteride and oral minoxidil doesn’t work that’s it right?

      in Treatment  41 upvotes 2 years ago
      A user is experiencing ongoing hair loss despite using 0.5mg dutasteride and 2.5mg oral minoxidil for several years and is seeking advice. Suggestions include ensuring correct diagnosis, checking for other health issues, considering finasteride, trying topical antiandrogens, and consulting a dermatologist.

      community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

      in Research/Science  739 upvotes 3 years ago
      A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.

      community 22 years since the last major development

      in Technology  51 upvotes 5 years ago
      The conversation discusses the lack of significant advancements in hair loss treatments since the introduction of finasteride 22 years ago, with many expressing frustration over the failure of new projects and skepticism about future developments. Some users mention hair transplants and other potential alternatives like Alfatradiol and Fluridil, but acknowledge finasteride's dominance in the market due to its effectiveness and affordability.

      community 6 years on Fin. This shit is goated.

      in Finasteride/Dutasteride  140 upvotes 3 months ago
      Finasteride is effective for maintaining hair and stopping hair loss, with many users experiencing long-term success and minimal side effects. Some users consider switching to Dutasteride or adding Minoxidil for additional regrowth.

      community Has anyone seen the data on this 539% boost breakthrough?

      in Technology  867 upvotes 5 months ago
      Topical Clascoterone showed a 539% improvement in hair count compared to placebo, but its effectiveness and safety are debated. Users compared it to minoxidil and finasteride, with mixed opinions on its potential release in 2026 or 2027.

      community Not feeling very optimistic about progress

      in Is this regrowth?  19 upvotes 8 months ago
      A 19-year-old is using finasteride, dutasteride, and minoxidil to combat hair loss, seeing improved hair density but minimal hairline regrowth. Users suggest patience, continued treatment, and possibly considering a hair transplant in the future.

      community My Theory Of Androgenic Alopecia

      in Research/Science  20 upvotes 8 months ago
      Hair loss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.

      community Why didn’t Justin Bieber boof his finasteride

      in Satire  723 upvotes 8 months ago
      Justin Bieber's hair loss and his choice not to use finasteride or other treatments like rectal injection are discussed, with reasons speculated to be side effects or lack of concern. The conversation also mentions his past hair transplant and suggests his wealth and fame might make appearance less of a priority.

      community Completely Lost with my hair 20M

      in Progress Pictures  35 upvotes 10 months ago
      A 20-year-old experiencing hair loss uses minoxidil, Nizoral shampoo, vitamin D, and biotin. They are considering finasteride or dutasteride and are advised to consult a doctor for diagnosis and possible oral treatments.

      community Dht kills hair, but no one says why?

      in Finasteride/Dutasteride  40 upvotes 10 months ago
      DHT affects hair follicles, contributing to hair loss, but the exact mechanism is unclear. Treatments like finasteride and minoxidil are used to manage hair loss, though they may have side effects and varying effectiveness.

      community 8 months apart - got all my hair back.

      in Update  4799 upvotes 1 year ago
      A user successfully regrew their hair over 8 months using topical minoxidil, finasteride, a healthy lifestyle, and derma stamping. They emphasize the results are genuine and not from hair transplants.

      community 8 months on oral minoxidil. No sign of regrowth.

      in Minoxidil  14 upvotes 1 year ago
      The user has been taking 2mg oral minoxidil and 1mg finasteride but has seen no hair regrowth after 8 months, leading to concerns about being a non-responder. They are considering increasing the minoxidil dosage or switching to dutasteride, while also using keto shampoo and microneedling, but remain skeptical about the effectiveness of minoxidil.