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      community Sooo whats the consensus about pp405 now?

      in Chat  75 upvotes 2 months ago
      PP405 may help with hair regrowth, especially when combined with minoxidil and finasteride, but its long-term effectiveness is unclear. Phase 3 trials are expected to begin soon, with results in a few years.

      community Reducing Fibrosis in Hair Loss: Topical Pirfenidone

      in Research/Science  58 upvotes 2 months ago
      Topical pirfenidone is highlighted as an effective anti-inflammatory and anti-fibrotic treatment for hair loss, particularly in addressing perifollicular fibrosis, which may enhance the effectiveness of standard treatments like finasteride and minoxidil. The user also uses calcipotriol, MCT oil, ciclopirox shampoo, and benzoyl peroxide shampoo as part of their regimen.

      community I just got one of these. Let's see how it goes...

      in Technology  263 upvotes 3 months ago
      Red light therapy for hair loss is controversial, with mixed results reported. Its effectiveness may depend on device quality and proper wavelength, and it is often used with minoxidil and finasteride.

      community 2 months of nightly 5% minoxidil

      in Progress Pictures  485 upvotes 4 months ago
      A 25-year-old user shared progress after two months of using 5% minoxidil nightly on their scalp and beard. Many users suggest combining minoxidil with finasteride or dutasteride to prevent hair loss due to DHT, while others express concerns about potential side effects of these DHT blockers.

      community When results are great, but you're looking for excellent

      in Chat  3 upvotes 4 months ago
      The user improved hair density from 45% to 70% using dutasteride and minoxidil, but still uses hair fibers for a fuller look. They added a topical mix of minoxidil, finasteride, and bimatoprost, but doubt further significant improvement.

      community 2 months in, I think it's working

      in Progress Pictures  817 upvotes 4 months ago
      The user reported positive progress in hair regrowth after two months using finasteride, topical minoxidil, microneedling, and ketoconazole, later switching to dutasteride. Some users doubted the authenticity of the results, while others were impressed and encouraged by the progress.

      community Alternatives/unorthodox hairloss protocols to the big three

      in Chat  1 upvotes 5 months ago
      The conversation discusses alternative and unorthodox hair loss treatments, including RU58841, nandrolone, and dianabol, as well as theoretical approaches involving high doses of estrogen and selective estrogen receptor modulators. These methods are considered extreme and potentially harmful but are explored for those unable to tolerate traditional 5-alpha reductase inhibitors.

      community Alternatives to Minox for pet safety

      in Minoxidil  2 upvotes 5 months ago
      The conversation discusses alternatives to minoxidil for beard growth, focusing on a product called Neofollics Beard Growth Serum, which claims to be effective without using minoxidil. Concerns are raised about its ingredients and effectiveness, especially considering pet safety.

      community Clascoterone 5% solution infographic

      in Update  132 upvotes 6 months ago
      Clascoterone 5% solution is discussed as a potential new treatment for hair loss, offering an alternative for those who can't use finasteride or need additional options beyond minoxidil. Concerns about cost, effectiveness, and safety compared to existing treatments like RU58841 and finasteride are highlighted.

      community Thoughts on the future of pp405?

      in Research/Science  43 upvotes 7 months ago
      PP405 is considered a promising hair loss treatment, potentially replacing minoxidil but not finasteride. Users are hopeful for future treatments like GT20029 and VDPHL01, while remaining cautious about effectiveness and side effects.

      community It's so over. Im beyond cooked

      in Update 7 months ago
      The user is experiencing hair loss despite using Dutasteride and plans to try RU58841, considering adding Oral Minoxidil. They express frustration with diffuse thinning and seek advice on managing hair loss.

      community Using a Dermaroller saved my hair

      in Microneedling  456 upvotes 7 months ago
      Using a dermaroller with topical minoxidil and oral finasteride regrows hair and improves temple areas. Users highlight the benefits of microneedling tools and stress the importance of consistency and proper sanitation.

      community Is Vitamin D the cause of my baldness or slow regrowth?

      in Is this regrowth?  1 upvotes 7 months ago
      The conversation discusses hair loss treatments, including oral finasteride, topical minoxidil, and microneedling, and the potential impact of Vitamin D and folic acid deficiencies on hair regrowth. It suggests that while male pattern baldness is the primary cause, addressing vitamin deficiencies may aid in improving regrowth.

      community Running Gear- Preemptive Treatment

      in Product 8 months ago
      A 51-year-old on TRT plans to use steroids and is concerned about hair loss, considering topical treatments like Hair Rescue with RU58841 and finasteride, along with Nioxin shampoo. They are cautious about using oral DHT blockers due to potential interactions with steroids like Tren and Anavar.

      community 5+ years on meds, still losing

      in Progress Pictures 8 months ago
      The user has been on finasteride and minoxidil since 2020 and increased dutasteride and minoxidil doses in June 2024, but still experiences hair loss. Despite trying pyrilutamide without success, opinions vary on whether the hair loss is significant, with some suggesting it might be due to lighting, angles, or a regular shedding cycle.

      community The amazing fast pace of PP405.

      in Chat  327 upvotes 8 months ago
      PP405 is a new hair loss treatment advancing quickly in trials, generating excitement and skepticism about its effectiveness and marketing claims. Some see it as a potential alternative to minoxidil and finasteride, but concerns about long-term effects and the need for DHT blockers persist.

      community 34M - 11 years on finasteride 9 months 5mg oral minoxidil

      in Chat  179 upvotes 9 months ago
      The user successfully maintained and regrew hair using finasteride for 11 years and oral minoxidil for 9 months, experiencing no significant side effects. They plan to continue these treatments to prevent hair loss.

      community Should I risk changing to Dutasteride?

      in Finasteride/Dutasteride  10 upvotes 9 months ago
      The user is considering switching from Finasteride to Dutasteride for better hair regrowth, despite concerns about potential shedding and side effects. Opinions vary, with some suggesting the switch for stronger results and others advising caution due to possible side effects and the importance of consulting a doctor.