The conversation is about frustration over the delay in phase 2 results for a hair loss treatment called GT20029. One user suspects the treatment may have failed.
A 30-year-old male with thinning hair and an itchy, oily scalp found that hydrocortisone cream eliminated dandruff and itching and seemed to thicken his hair. He avoided minoxidil and finasteride due to potential side effects and noted that Nizoral and Head & Shoulders worsened his symptoms.
The importance of lighting when taking progress pictures and discussing hair growth, as dramatic changes can be seen even without real improvements. The users also discussed methods such as Fin min and dermarolling for treating hair loss.
Hair loss discussion includes potential HMI-115 treatment. Topical mucuna pruriens shows good results, blocking prolactin possibly more important than blocking DHT.
The conversation discusses using GHK-Cu for hair loss, with one user suggesting subcutaneous administration for better control. The effectiveness of topical application is questioned due to a lack of reliable reviews.
A 38-year-old male with stress-induced Telogen Effluvium is seeking advice on using oral finasteride and minoxidil, as well as vitamin regimens, for hair loss. He is considering these treatments after a dermatologist ruled out male pattern baldness and prescribed ketoconazole shampoo.
Treatments for hair loss, specifically the use of minoxidil, finasteride and RU58841. Replies to this post suggest that users should share relevant information publicly rather than through direct messages.
2 Deoxy D Ribose may promote hair growth and aid wound healing, potentially enhancing microneedling effects. Users discuss its combination with microneedling for better hair growth results.
Switching milk brands cleared scalp inflammation and other symptoms, but hair shedding continues. The user hopes shedding will stop as hair cycles progress.
Follistatin, known for inhibiting myostatin and promoting muscle growth in mice, is being discussed as a potential treatment for hair loss. Specific treatments mentioned include Minoxidil, Finasteride, and RU58841.
Hmi115, a prolactin receptor blocker, showed promise for hair growth, but results from Phase 2 trials have not been published. ABS-201, an AI-based analog, is expected to begin trials in December 2025, while commercialization of treatments like PP-405 is anticipated around 2027.
Finasteride and minoxidil are effective for hair growth, but increasing testosterone, even naturally with ashwagandha, may increase DHT, potentially affecting hair loss if predisposed to male pattern baldness. Testosterone replacement therapy (TRT) can be beneficial for energy and muscle gain but may expedite hair loss if already prone to it.
The conversation discusses the potential effectiveness of a Sult1a1 enzyme booster in enhancing the results of minoxidil for hair loss. Users express interest in the booster, hoping it will improve the effectiveness of oral minoxidil, especially for those who struggle with topical application.
A 24-year-old male experienced an increase in estradiol levels and symptoms like gynecomastia and excessive sweating after using Minoxidil for hair loss. His estradiol levels decreased after he stopped using Minoxidil.
Volume boost shampoos, specifically Schwarzkopf Professional Bonacure Collagen Volume Boost Micellar Shampoo, may potentially impact hair due to creatine's effect on DHT. The user likes the shampoo for its gentle nature and thickening effect but is concerned about long-term use.
The conversation discusses the use of peptides C60 and GHK-Cu for hair growth. Participants are sharing their experiences or knowledge about these treatments.
A user experienced burning, itching, and soreness on their scalp after a perm in 2021, despite using oral finasteride, oral minoxidil, and ketoconazole shampoo. They are seeking advice on whether to pursue further medical tests or consult a neurologist for nerve pain.
The conversation is about a user seeking advice on adding GHK-Cu to RU58841 for hair loss treatment, while already using oral minoxidil, dutasteride, ketoconazole shampoo, and considering LLLT. They are unsure about the concentration and carrier solution for GHK-Cu.
Stem cell hair restoration lacks scientific evidence and is often considered a scam. Effective hair loss treatments include hair transplants, Minoxidil, and Finasteride, but stem cell treatments are not proven.
Hair loss treatment involves gland treatment with iodine, liver extract, wild American ginseng, and black cohosh, along with crude oil scalp massage. The approach aims to stimulate hormones and improve blood circulation to promote hair growth.
White rice may lower DHT and potentially cause symptoms similar to post-finasteride syndrome. The user experienced muscle wasting, depression, and other symptoms after consuming large amounts of white rice.
The user is experiencing reduced hair shedding and increased hair density after using finasteride, minoxidil, derma rolling, granactive retinoid, and Nizoral, while also taking testosterone and aromatase inhibitors. They question if they are a hyper responder to the treatments, despite mixed feedback from others about visible progress.
The user has been using finasteride, dutasteride, and RU58841 for hair loss without success and feels extremely uncomfortable with their appearance, including being bald and short. They express deep unhappiness and social isolation. Suggestions from others include adopting stoicism, focusing on personal development, considering a hair system, improving fashion, working out, and seeking therapy for mental health.
The user started using oral minoxidil and estradiol in August 2025, added finasteride in December, and experienced significant hair shedding in February/March. They switched to estradiol injections and are considering their hair washing routine, while another user suggested consulting a dermatologist and possibly trying dutasteride.
Stopping finasteride may reduce water retention or alter fat distribution, leading to a leaner face. Hormonal changes, like reduced DHT or increased estrogen, could cause these effects.