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      community Topical rapamycin, metformin, a-kg grow hair

      in Research/Science  14 upvotes 5 years ago
      The conversation discusses the potential of topical rapamycin, metformin, and alpha-ketoglutarate (a-KG) for hair growth, with skepticism expressed about their effectiveness based on personal experience and existing use. It also mentions AICAR, known as cardarine or GW, which is not suitable for long-term use due to cancer risks in animal studies and its similarity to metformin.

      community Autoimmune issue?

      in Question  2 upvotes 8 years ago
      The user experienced severe hair loss, itchy scalp, and skin issues after trying no-shampoo, and wonders if it's male pattern baldness or an immune issue. They have a history of eczema, dermatitis, and jock itch, and have tried various treatments like coconut oil, peppermint, pumpkin seed, and onion.

      community About GT20029's Efficacy and Strength

      in Chat  8 upvotes 3 years ago
      The conversation is about the effectiveness and production of GT20029, a drug being developed as a topical androgen receptor degrader for hair loss, and whether it can fully degrade androgen receptors or only partially. It also discusses the drug's potential unique working mechanism and synthesis by a company called Anagen.

      community Potential role of TB-500 Thymosin Beta-4

      in Technology  8 upvotes 1 year ago
      The conversation discusses hair loss treatments, specifically mentioning Minoxidil, finasteride, RU58841, and TB-500 Thymosin Beta-4. It critiques the credibility of biohacking claims.

      community Anyone heard of Exosome stem cell treatment?

      in Treatment  1 upvotes 1 year ago
      Exosome stem cell treatment for hair loss, which is expensive and reportedly effective, but its popularity has declined. The conversation also mentions Minoxidil, finasteride, and RU58841 as treatments.

      community My Hair loss/regrowth Journey Since 2017

      in Progress Pictures  9 upvotes 1 year ago
      The user shared their hair regrowth journey since 2017, using treatments like finasteride, minoxidil, dutasteride, RU58841, microneedling, and later feminizing HRT. Significant progress was noted after starting HRT, with continued improvement in hair texture and regrowth.

      community Androgen degraders for hair loss

      in Research/Science  60 upvotes 1 year ago
      The conversation discusses androgen receptor degraders for hair loss, highlighting their potential advantages over traditional AR blockers like RU58841 and pyrilutamide. Concerns about the safety and cost of these treatments are also mentioned.

      community 14 Week Progress - Bald spot--gone! Hair much darker this month... Hairline going from rounded to pointed at the temples

      in Progress Pictures  73 upvotes 8 months ago
      A 29-year-old is using 5% topical minoxidil, 5 mg oral minoxidil, 1 mg finasteride, Nizoral shampoo, and weekly microneedling to treat hair loss, reporting significant progress in hair regrowth and hairline improvement. The routine includes applying minoxidil twice daily, managing dead skin with shampoo, and using a baseball cap to maintain hair appearance.

      community 18 month crown update progress pictures

      in Progress Pictures  424 upvotes 1 year ago
      The user has seen significant hair regrowth using a routine of minoxidil, finasteride, microneedling, scalp massage, and Nizoral. They are considering adding red light therapy and PRP to their regimen.
      The story of RU58841/ PSK3841

      community The story of RU58841/ PSK3841

      in Research  622 upvotes 1 year ago
      RU58841, a potential hair loss treatment, was not commercialized due to marketability issues and lack of long-term safety data. Concerns about its formulation and delivery methods further complicate its use.

      community Micronutrient testing, deficiencies, etc.

      in Treatment  4 upvotes 3 years ago
      Micronutrient testing and deficiencies related to hair loss, particularly androgenetic alopecia (AGA). Discussion includes the impact of iron, selenium, zinc, copper, folate, B12, vitamin E, vitamin D, amino acids, and fatty acids, alongside treatments like dutasteride or finasteride.

      community My dermatologist gave me Ell cranell?

      in Treatment  4 upvotes 2 years ago
      The user is seeking advice on a hair loss treatment called Ell Cranell, which contains Alfatradiol. Another user shared information from a study stating that Alfatradiol only slows down or stabilizes hair loss, but does not increase hair density or thickness.

      community 6 months progress, 4600 grafts in Turkey

      in Progress Pictures  200 upvotes 2 years ago
      The user is happy with their 6-month hair transplant progress of 4600 grafts in Turkey and has been using finasteride for 5 years and minoxidil for 4 years. The donor area is in good condition, potentially allowing for future hair reinforcement.

      community 12 months of progress (min+ fin)

      in Progress Pictures  97 upvotes 2 years ago
      Hair loss progress after 12 months using minoxidil, finasteride, and microneedling. Goal is to maintain and improve hair until old enough for hair transplant.

      community Forgotten 'Total Revival' Stack

      in Research/Science  42 upvotes 11 months ago
      Cyclosporine A is discussed as a powerful hair growth stimulant, potentially more effective than minoxidil, but concerns about safety and side effects, including cancer risk, limit its use. The conversation highlights the need for further research and experimentation with topical application, despite its risks.

      community What do we actually know about HMI-115?

      in Chat  16 upvotes 2 years ago
      The post and conversation are about HMI-115, a potential treatment for hair loss. The conclusion is that HMI-115 is not a 5ar-inhibitor and is instead a prolactin receptor inhibitor. Some users are skeptical about its effectiveness and believe that baldness will still be a problem in the future.

      community Clascoterone for hair loss. Promising study.

      in Treatment  12 upvotes 4 months ago
      A new topical medication, Clascoterone, shows promise for hair loss, improving hair count significantly. Trials for Breezula are ending, but sign-ups for PP405 trials are available for 2026.

      community Female male-pattern AGA- seeking help

      in Female  1 upvotes 2 years ago
      A female with male-pattern hair loss (AGA) is seeking help after unsuccessful treatments with spironolactone and supplements, and is considering oral minoxidil and finasteride despite concerns about medication side effects. She has ruled out hormonal birth control and PRP/PRFM, and is looking into further medical advice due to abnormal lab results.

      community Bloodflow/Natural Remedies for receding hairline

      in Research/Science  5 upvotes 1 year ago
      A 30-year-old male successfully stopped hair loss and improved hair density using red light therapy, saw palmetto, vitamins, L-Arginine, fish oil, derma rolling, and specific shampoos, after experiencing negative effects from minoxidil and finasteride. He emphasizes focusing on blood flow and natural remedies, noting significant improvements in hair and beard fullness.

      community Counter-update: Cbum's transplant DOESNT look super good now

      in Transplants  221 upvotes 11 months ago
      Cbum's hair transplant is criticized for looking unnatural and not blending well, with some suggesting better results were expected given his resources. Discussions also cover the effects of steroids and finasteride on hair loss and muscle growth.