The user shared their one-year transformation using finasteride 1 mg daily and topical minoxidil once a day, noting initial side effects like reduced sex drive that later subsided. They observed hair improvement after 3-4 months, with no significant shedding beyond normal hair loss during detangling.
The user's first hair transplant failed, and they are preparing for a second one. They are considering whether to continue multivitamins and B complex before the surgery, and are asking for advice on supplements to take for hair loss that do not include DHT blockers, finasteride, minoxidil, or high-dose biotin, and are contemplating iron, folic acid, vitamin C, and NAC for before and after the surgery.
Hair loss discussion involves experimenting with Sulforaphane from broccoli sprouts and possibly procyanidin b2. People seek updates on progress and if it's worth adding to treatment stack like microneedling.
A user's successful hair regrowth journey using a cocktail of finasteride, minoxidil, and ketoconazole. The user started seeing noticeable results after 8 months and also incorporated saw palmetto, biotin, keratin, and dermarolling into their routine.
A user received a prescription for a topical solution with Minoxidil 7%, Finasteride 2%, and Tretinoin 0.01%, to be used twice daily for three months. They are concerned about the safety of these dosages compared to commonly recommended lower dosages.
PP405 is a potential hair loss treatment that inhibits mitochondrial pyruvate carriers, increasing lactate dehydrogenase activity and stimulating hair follicle stem cells. In a phase 1 trial, 31% of participants showed over 20% hair density increase with PP405 treatment.
The conversation discusses switching from finasteride to dutasteride due to side effects, with some users experiencing fewer side effects on dutasteride. It also mentions using liposomal topical finasteride and ketoconazole shampoo as alternative treatments.
The user has been using oral finasteride daily, topical minoxidil twice a day, tretinoin once a week, and 2% ketoconazole twice a week since February 5th. They shared progress pictures showing hair improvement over two and a half months.
A user's journey to treat hair loss with a combination of oral medication, topical treatments, microneedling and different shampoos and supplements. It includes warnings about an OGX biotin shampoo potentially causing further hair loss.
Reducing the dose of Pyrilutamide from 5mg to 2.5mg may still maintain hair loss results, but effectiveness can vary. Users discuss the cost and dosage implications, with some cautioning against reducing the dose due to its dose-dependent nature.
Tae147 has shared results of using pyrilutamide, a 5% concentration topical solution applied twice daily, in combination with minoxidil, to reduce scalp itchiness and hair shedding. Other users have shared their experiences with the treatment, as well as questions about its availability on the market.
Dutasteride and finasteride are not effectively stopping hair loss for some users, despite long-term use. Some are considering or using RU58841, pyrilutamide, and other treatments like microneedling, while also managing seborrheic dermatitis with diet and topical solutions.
An 18-year-old has been using minoxidil and finasteride for hair loss since age 15, recently adding dutasteride and GHK-Cu, but sees no significant improvement and is considering a hair transplant. Concerns are raised about using hormone suppressors at a young age, with suggestions to explore other treatments like dermarolling, diet changes, and checking for deficiencies.
Dutasteride Mesotherapy for hair loss is discussed, noting its potential to lower scalp DHT without side effects. Concerns include the inconvenience of injections, lack of reputable studies, and availability issues.
The user is experiencing side effects like light-headedness and breathlessness from taking Dutasteride, Minoxidil, and Biotin orally. They are considering taking the medication at night to alleviate these symptoms.
A user from China is participating in a clinical trial for Pyrilutamid, a potential hair loss treatment originally developed for prostate cancer. They've experienced no side effects except initial scalp itchiness, and will share results after the year-long trial.
A user's 2.5 year transformation of using 0.5mg finasteride and RU58841 to combat hair loss, with the possibility of increasing the RU for further regrowth.
Some people have side effects from finasteride and dutasteride due to hormonal predisposition, especially if DHT dominant. Alternatives like RU58841, Pyrilutamide, and Breezula are suggested to target scalp androgen receptors without altering overall hormones.
A user is using a Finoxidil topical spray and is curious if oral Finasteride would be more effective, considering they are already on a DHT blocker called Cyproterone. They are concerned about the potential impact of oral Finasteride on their transition.
Finasteride was intentionally developed to treat BPH and later approved for male pattern baldness (MPB) due to its 5AR inhibition effects. The delay in MPB approval was due to concerns about off-label use for female hirsutism and the prioritization of treating a more debilitating condition.
The user healthydudenextdoor starting a new topical anti-androgen hair loss treatment, Pyrilutamide, and discussing their current regimen of finasteride and minoxidil.
A 26-year-old male shared progress photos showing hair improvement after nearly 5 months on oral Minoxidil (4mg), Dutasteride (0.5mg), and biotin (4mg). The photos show noticeable hair growth over time.
A peptide from Japanese water chestnut fruit may help with hair loss by suppressing DHT's effect on hair follicle cell death, potentially serving as a finasteride alternative. The treatment's effectiveness and safety in humans remain uncertain.
A 21-year-old user has been using finasteride 1mg daily since March 11 and ketoconazole 1% 2-3 times a week since April 22, with no significant side effects. They are questioning if they are seeing early hair regrowth after 2.5 months of treatment.
The user shared progress on hair loss treatment between September and November using oral finasteride, topical minoxidil, dermarolling, a LaserComb, caffeine shampoo, Nizoral, scalp massages, and both oral and topical biotin. The conversation discusses the effectiveness of these treatments.
A user experienced increased testosterone and estradiol levels after starting finasteride/dutasteride and is asking if these levels will return to normal over time. The conversation focuses on whether these changes are temporary.
A user shared their 5-month hair loss treatment progress, using 1mg finasteride, daily GHK-CU injections, keratin/biotin/MSM supplements, Pura D’Or shampoo and conditioner, Ayurvedic oil, ketoconazole thrice weekly, and weekly microneedling with topical GHK-CU. The post includes progress pictures.
A user is seeking advice on treating a chin scar with Verteporfin, noting that higher doses were more effective. Another user responds that they do not use it, without providing further explanation.
Pyrilutamide's 0.5% solution showed minimal improvement, while the 1% solution appears more promising but costly. The user is currently using finasteride and oral minoxidil and considering adding Pyrilutamide if effective and affordable.