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      community PP405 Might Be the Closest We Have to a Upcoming Cure

      in Technology  237 upvotes 1 year ago
      PP405 is considered a promising potential cure for hair loss, with phase 2 trial results expected in February 2025. Hair cloning is also discussed as a potential ultimate solution, despite significant scientific challenges.

      community Dermatitis and Nizoral

      in Ketoconazole 6 years ago
      A 27-year-old male experienced hair loss and dermatitis, which improved with tea tree oil and neem extract. He is considering using a 2% Ketoconazole solution for further treatment.

      community Shiseido RCH-01

       7 upvotes 7 years ago
      Shiseido RCH-01 and Replicel's upcoming trial data release. Users discuss expected release timelines and clarify quarter dates.

      community Hair theory Scar tissue and Verteporfin

      in Chat  25 upvotes 1 year ago
      A user suggests that deeper microneedling with Verteporfin injections might help regrow hair in areas with scar tissue, alongside a DHT blocker. Another user explains that hair loss might be due to reduced Wnt/β-Catenin signaling and suggests that treatments like Minoxidil, Finasteride, and microneedling could potentially reverse it.

      community Shedding on pyri (KX-826) is this normal?

      in Update  8 upvotes 1 year ago
      A user experienced increased shedding after adding KX-826 to their long-term finasteride and minoxidil regimen. Another user reported mild side effects from KX-826, such as stomach and testicle pain.

      community Quote from Pelage (PP-405) Spokesperson...

      in Research/Science  120 upvotes 5 months ago
      Pelage is developing a topical hair follicle stem cell therapy, PP405, for non-scarring alopecias like androgenetic alopecia, with Phase III trials planned and a potential market launch by 2027. The treatment may not require continuous use after initial regrowth.

      community PP405 Hair Loss Drug: Phase 1 Human Results & Biopsy Insights

      in Research/Science  213 upvotes 1 year ago
      PP405 is a potential hair loss treatment undergoing trials, with discussions on its effectiveness and comparison to existing treatments like finasteride and minoxidil. There is skepticism about its status as a cure, with hopes for future advancements in genetic treatments like CRISPR.

      community Before, and my last 3 hair styles over 2 years. (Hair system)

      in Hair Systems  537 upvotes 1 year ago
      A user shared their experience with hair loss, initially using finasteride and minoxidil without satisfactory results, and later switching to hair systems, which they plan to use indefinitely. The user and others discussed the positive reactions, maintenance, and normalization of hair systems for men.

      community My experience and a discourse on “DUPA”

      in Chat  46 upvotes 3 years ago
      How diffuse unpatterned alopecia (DUPA) is not an invitation to self-diagnose oneself with aggressive AGA and that seeking a specialized dermatologist may help people experiencing hair loss. Treatment options discussed include topical clobetasol propionate, oral minoxidil, and discontinuing finasteride.

      community Anyone have experience with GHK-CU

      in Product  7 upvotes 2 months ago
      GHK-Cu is being considered for hair growth, but users report mixed results. Some use it alongside other treatments like 5AR inhibitors, making it hard to determine its effectiveness.

      community Microneedling + topical fin/min: how to structure the routine?

      in General  78 upvotes 6 months ago
      The user is using a topical spray containing finasteride, minoxidil, ketoconazole, and biotin for hair loss and plans to add weekly dermastamping, starting with a needle length of 0.6mm. They seek advice on the safety of combining these treatments, the impact of skipping one dose weekly, and the frequency of replacing the dermastamp.

      community The mystery of Azelaic Acid

       5 upvotes 10 years ago
      The conversation discusses using Rogaine (Minoxidil) and ketoconazole for hair regrowth, with interest in trying a formulation with Azelaic Acid for potentially better results. Concerns about Azelaic Acid's effectiveness and safety, including skin sensitivity to sunburn, are mentioned.

      community RU58841 KB Solution vs PG + Ethanol

      in Research/Science  5 upvotes 2 years ago
      The conversation discusses the differences between KB solution and PG + Ethanol solution for RU58841 in treating hair loss. It compares the effectiveness and properties of these two solutions.

      community Hair loss whodunit: help me find the culprit!

      in Treatment  9 upvotes 3 years ago
      The user is experiencing hairline thinning despite using finasteride, minoxidil (solution and foam), dermastamping, and tretinoin. They suspect minoxidil or tretinoin might be causing the issue but are unsure.

      community New Hair Loss Cure: AMP-303 Is Back. It’s what PP405 should have been.

      in Research/Science  1 upvotes 1 week ago
      AMP-303 and AMP-601 are new hair loss treatments targeting dermal papilla cells, with AMP-303 showing early efficacy in transitioning vellus hairs to terminal hairs after one injection. Further clinical trials are planned, and these treatments are seen as promising due to their biologic approach and less frequent application compared to daily treatments.

      community Has anyone tried hair+me topicals? (UK)

      in Treatment  1 upvotes 6 months ago
      The user is trying Hair + Me's 5% minoxidil and 0.1% finasteride topical, which has a different carrier and pleasant smell compared to traditional alcohol-based formulas. They are seeking feedback on its effectiveness compared to classic formulas.

      community 5% capixyl 3%redensyl+procapil

      in Product  5 upvotes 2 years ago
      The conversation is about a hair loss serum mix containing 5% capixyl, 3% redensyl, and procapil. The user is asking for recommendations or opinions on the effectiveness of this product.

      community Sharing what worked for me (PCOS related hair loss)

      in Female  35 upvotes 2 years ago
      A user with PCOS experienced hair loss and found success using a triple dose of O.N.E Omega by Pure Encapsulations after discovering low Omega fatty acids. Biotin provided minimal improvement, but the Omega supplement significantly restored hair.

      community Another blow to the cursed baldness

      in Research/Science  91 upvotes 6 months ago
      A South Korean company, Therazyne, has developed a promising hair loss treatment using a WNT chain surrogate that binds to Frizzled 7, with human follicle testing expected soon. Current treatments like minoxidil and finasteride are not seen as cures, and while optimism exists for future solutions like PP405, approval processes are lengthy.