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    Did you mean Diastolic Blood Pressure?
    GlossaryDiastolic Blood Pressure

    pressure in arteries when heart rests between beats

    Diastolic Blood Pressure (DBP) is the pressure in the arteries when the heart is at rest between beats. It is the lower of the two numbers in a blood pressure reading, with the other being systolic blood pressure. For example, in a reading of 120/80 mmHg, the 80 represents the diastolic pressure. This measurement is crucial for assessing cardiovascular health, as consistently high diastolic pressure can indicate an increased risk of heart disease and stroke.

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      community Is oral minoxidil f***ing me up?

      in General  269 upvotes 5 months ago
      Oral minoxidil is causing significant blood pressure fluctuations and increased heart rate, leading the user to consider switching to topical minoxidil and tretinoin. The user plans to consult a cardiologist and is likely to stop using oral minoxidil.

      community The Fear of Oral Minoxidil is Overblown

      in Research/Science  272 upvotes 11 months ago
      Low-dose oral minoxidil is a safe and effective hair loss treatment with fewer side effects than previously feared. Users often prefer it over topical minoxidil for better results, though some experience side effects like increased body hair and cardiovascular issues.

      community My Journey on Fin + Min (19M giving up)

      in Finasteride/Dutasteride  20 upvotes 1 year ago
      A 19-year-old tried oral minoxidil and finasteride for hair loss but experienced side effects like fatigue, dry eyes, and lack of motivation, leading to discontinuation. Suggestions included trying topical treatments, dutasteride, or accepting hair loss.

      community P-1075: a BETTER version of Minoxidil

      in Research/Science 7 months ago
      P-1075 is a more potent hair growth agent than Minoxidil, but it poses significant heart risks, making it unsafe for use. Despite promising results in macaques, concerns about its cardiotoxicity in rats have halted its development.

      community Lowering dose of Oral Minoxidil?

      in Minoxidil  108 upvotes 1 year ago
      The user plans to lower their oral minoxidil dose from 5 mg to 2.5 mg to reduce side effects like puffiness and hypertrichosis, while also using finasteride and accutane. They are considering caffeine serums for puffiness and discussing dietary changes or switching to topical minoxidil to address bloating.

      community 2 year progress with Dut after a decade of Fin

      in Finasteride/Dutasteride  150 upvotes 3 weeks ago
      A user shared their hair loss journey, using finasteride since age 18 and adding dutasteride at 30, which halted hair loss and promoted regrowth. They take finasteride daily and dutasteride three times a week, experiencing reduced libido and drier skin as side effects.

      community Anyone read oral minoxidil's leaflet?

      in Minoxidil  4 upvotes 1 year ago
      Oral minoxidil is discussed, highlighting potential cardiovascular risks at high doses, but users note that lower doses commonly used for hair loss are generally considered safe. Monitoring by doctors is advised, and some users report taking it without issues, comparing its risks to those of common medications like ibuprofen.

      community Why is regrowth impossible for me? What else can I do?

      in Progress Pictures  23 upvotes 1 year ago
      The user is frustrated with hair regrowth despite using finasteride, minoxidil, dutasteride, RU58841, ketoconazole shampoo, and dermastamping. Others suggest improvement, advise against overmedication, and recommend consulting a doctor or considering a simpler regimen or hair transplant.

      community New 2025 study: high dose oral minoxidil (up to 10mg)

      in Research/Science  80 upvotes 8 months ago
      High-dose oral minoxidil (>5 mg/day) can increase hair density in some men with androgenetic alopecia, but side effects like extra body hair and heart issues are common. Gradual dose increase is advised, but adverse effects may lead to discontinuation or dose adjustments.

      community High blood pressure issue with Dr?

      in General  93 upvotes 9 months ago
      A 48-year-old male is experiencing hair loss despite taking finasteride for four months. He is considering oral minoxidil but is concerned about high blood pressure and is unsure about taking spironolactone.

      community High Estrogen and Test on Dut 5x a week

      in Finasteride/Dutasteride  6 upvotes 1 year ago
      A user experienced increased pimples and cysts after two years on dutasteride, possibly due to hormonal changes. Suggestions included seeing an endocrinologist, using supplements like boron and DIM, adjusting diet, and reducing body fat to manage side effects.

      community High Nicotine use and Hair Loss

      in Chat  91 upvotes 1 year ago
      Heavy nicotine use can lead to hair thinning and loss, but quitting can reverse these effects. The user noticed significant hair regrowth after quitting vaping.

      community high bloodpressure and crown thinning in early 20s

      in Is this regrowth?  9 upvotes 2 years ago
      A user with kidney disease and high blood pressure experienced hair thinning, especially around the vertex. They are currently using finasteride and oral minoxidil but are considering whether to resume blood pressure medication despite managing symptoms with diet and exercise.

      community High DHT with finasteride. Help!

      in Finasteride/Dutasteride  6 upvotes 2 years ago
      Despite using 5% minoxidil, 0.1% finasteride, and other treatments like microneedling, MK-677, and Cialis, hair loss continues with high testosterone and DHT levels. Considering oral dutasteride but concerned about further increasing testosterone levels.

      community High Estrogen causing hair loss?

      in Treatment  16 upvotes 2 years ago
      A 24-year-old male using topical finasteride for hair loss is experiencing thinning despite treatment and has high estrogen levels. He is seeking advice on whether high estrogen could be causing hair loss and how others with high estrogen levels have addressed it.

      community high estrogen levels after 10month fin

      in Finasteride/Dutasteride  9 upvotes 2 years ago
      A user experienced high estrogen levels after 10 months of taking 1mg oral finasteride but is happy with hair regrowth. They are considering switching to topical finasteride and are also taking DIM and Zinc supplements.

      community High testosterone and diffuse hairloss

      in Treatment  6 upvotes 5 years ago
      The user is experiencing diffuse hair loss due to high testosterone levels and has tried various treatments including finasteride, minoxidil, nanoxidil, keto/caffeine shampoo, dermarolling, and RU-58841 with limited success. They are seeking advice on safely lowering testosterone levels to manage hair loss.

      community High Dose Niacin Update

      in Update  5 upvotes 8 years ago
      High dose niacin (1000mg daily) seems to have halted hair loss but did not regrow lost hair. The user plans to continue due to additional benefits like lower stress and higher good cholesterol.

      community High stress causing more shedding perhaps balding? 21(M)

       4 upvotes 12 years ago
      A 21-year-old male is experiencing hair shedding, possibly due to stress from a breakup, and is using minoxidil and drinking green tea to address it. Others suggest stress as a cause and recommend consulting a dermatologist if it persists.

      community Hair regrow idea: High dose Testosterone + RU58841

      in Satire  2 upvotes 1 month ago
      Using high doses of testosterone with RU58841 to create an androgen-free environment for hair regrowth is suggested, but concerns about heart health and the effectiveness of this approach are raised. Alternatives like topical estrogen, progesterone, and other treatments like finasteride and dutasteride are discussed.