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      community What's the deal with Zinc and DHT?

      in Chat  48 upvotes 2 years ago
      The conversation discusses the conflicting information about Zinc's effect on DHT and its role in hair loss. It mentions that Zinc can act as a 5AR inhibitor at high doses but may increase DHT if taken to correct a deficiency, and highlights the importance of nutritional balance for hair health.

      community Hair follicle dermal papilla exosomes

      in Treatment  2 upvotes 11 months ago
      The conversation discusses using hair follicle dermal papilla exosomes for hair loss treatment. It inquires about purchasing options for this treatment.

      community 16 months finasteride & minoxidil progress

      in Progress Pictures  605 upvotes 1 year ago
      User shared 16-month progress using finasteride 1 mg/day and minoxidil 5% solution once/day, noting significant regrowth, especially in temporal peaks. Users discussed shedding, side effects, and positive feedback from others.

      community 4 years apart (17-21) on treatment

      in Progress Pictures  40 upvotes 1 month ago
      A user shared their hair loss journey, starting treatments with topical minoxidil and finasteride at 17, and later adding oral versions and dutasteride by age 20, but still experiencing hair loss. Others suggested that the treatments have likely slowed the progression, and some recommended considering a hair transplant or adjusting medication, while expressing concerns about the potential side effects of starting such treatments at a young age.

      community KX-826 (Pyrilutamide) on Amazon

      in Treatment  9 upvotes 1 year ago
      The conversation is about purchasing KX-826 (Pyrilutamide) on Amazon, now called Koshine. A user mentioned their order is expected to arrive between August 22 and September 13.

      community H&W Topical Finasteride

      in Finasteride  7 upvotes 8 years ago
      Efforts to find a Canadian dermatologist in the US to prescribe H&W's topical finasteride for hair loss. The user is willing to fund a crowd-share effort to identify prospects.

      community Anyone tried adenosine for hair loss? Share your experience

      in Treatment  3 upvotes 3 months ago
      A user is seeking experiences with adenosine for hair loss, asking about its effectiveness, usage duration, and combination with treatments like minoxidil, finasteride, or RU58841. Another user mentions difficulty sourcing adenosine and comments on the mixed quality of research.

      community 4 months progress using 2.5mg min, 1mg fin and 10mg biotin.

      in Progress Pictures  42 upvotes 4 months ago
      A user shared their 4-month progress using 2.5mg minoxidil, 1mg finasteride, and 10mg biotin, noting slight testicular discomfort initially but no significant hairline changes yet. Another user reported similar treatment results, with hair darkening at the scalp center and small temple hairs.

      community 8-9 Month Update. 24M Korean Diffuse Thinner

      in Progress Pictures  311 upvotes 2 years ago
      The conversation discusses a 24-year-old Korean man's progress with hair loss treatments over 8-9 months, with specific treatments not mentioned due to redacted information. Users are commenting on the effectiveness and inquiring if Asians have better results with hair loss treatments.

      community Ketoconazole shampoo for early-stage shedding looks like working!

      in Ketoconazole  33 upvotes 10 months ago
      Ketoconazole shampoo may help with early-stage hair loss by stopping hair regression and promoting new hair growth, though its effectiveness as a DHT blocker is debated. Users report varying results, with some experiencing dryness and others seeing improvement when used 2-3 times a week.

      community Microneedling included as part of Big 4?

      in Question  7 upvotes 8 years ago
      Microneedling is considered an important addition to hair loss treatments like Finasteride, Minoxidil, and Nizoral, with evidence suggesting it enhances Minoxidil's effectiveness and can improve hair growth on its own. Users discuss various microneedling techniques, including heavy weekly sessions and lighter daily sessions, while expressing concerns about potential scalp damage and discomfort.

      community We already know how to permanently fix hair loss. The science is done. The only thing missing is the funding to run one experiment.

      in Technology  613 upvotes 1 month ago
      A permanent hair loss solution could involve reprogramming hair follicles to resist DHT using mRNA and siRNA. However, high costs, safety concerns, and the pharmaceutical industry's preference for ongoing treatments over one-time cures are major obstacles, with finasteride and minoxidil remaining standard treatments.

      community Kintor develop GT20026 Anti-Androgen receptor drug with NO SIDES

      in Treatment  18 upvotes 5 years ago
      The conversation discusses GT20029, a new topical drug for hair loss and acne without notable side effects, which has been accepted for investigational use in China. Some users express skepticism about the legitimacy of the company and the potential for other drugs like RU58841 to be developed due to patent expiration and lack of profitability.

      community 1 year Fin/2 months GHK-CU update

      in Update  128 upvotes 1 month ago
      The user has been using oral finasteride for over a year and recently added GHK-CU for two months, seeing progress but seeking further improvement, especially on the hairline. They discuss sourcing GHK-CU, its effects, and the importance of third-party testing, while considering additional treatments like dutasteride and hair transplants for better results.

      community A hill on which I will die: The DHT itch absolutely exists

      in Research/Science  210 upvotes 2 years ago
      The DHT itch is linked to hair loss and persists despite finasteride use; switching to dutasteride helped alleviate the itch and promoted regrowth. Some users suggest seborrheic dermatitis as a cause and recommend treatments like medicated shampoos, vitamin D, and minoxidil.
      18M: Oral Finasteride for 4.5 Months

      community 18M: Oral Finasteride for 4.5 Months

      in Journals / Progress Pictures  32 upvotes 7 months ago
      An 18-year-old has been using oral finasteride for 4.5 months to address hair thinning noticed since Fall 2022. They report the back of their head feels thicker, but are unsure if it's due to actual progress or placebo effect.

      community Progress since October 2023 to current

      in Treatment  5 upvotes 1 year ago
      A 40-year-old user shared their hair loss treatment progress since October 2023, using exosome treatment, minoxidil, finasteride, and microneedling. They started slacking on microneedling in February after stopping minoxidil.

      community 4 months progress – Fin, min, dermaroll, and nizoral

      in Progress Pictures  49 upvotes 3 years ago
      A 20 year old male's four month progress in treating his hair loss using finasteride, minoxidil, dermarolling and nizoral shampoo, as well as taking daily supplements such as Vitamin D, Zinc and Fish Oil. Replies were made expressing admiration for the results achieved.

      community 2021 vs 2024. Consistency is key.

      in Progress Pictures  1910 upvotes 1 year ago
      The user shared progress pictures showing significant hair regrowth from using finasteride, RU58841, and liquid minoxidil, emphasizing the importance of consistency. They noted that RU58841, a research chemical not FDA-approved, was effective when applied topically but warned of potential heart-related side effects.

      community Pp405 full presentation on new topical

      in Product  105 upvotes 2 months ago
      A new topical treatment, PP405, shows promising results for hair regrowth, potentially outperforming existing treatments like finasteride and minoxidil. However, it may still need to be combined with DHT blockers for optimal results, and its long-term effectiveness remains uncertain.