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      The story of RU58841/ PSK3841

      community The story of RU58841/ PSK3841

      in Research  622 upvotes 1 year ago
      RU58841, a potential hair loss treatment, was not commercialized due to marketability issues and lack of long-term safety data. Concerns about its formulation and delivery methods further complicate its use.

      community 18m 2.5 mg dut + topical min + 5 mg injectable ghk-cu progress. caught agressive loss early seemingly. may i have a few more years of handsomeness upon me.

      in Is this regrowth?  24 upvotes 8 months ago
      An 18-year-old is using a high-dose treatment for hair loss, including 2.5 mg dutasteride, topical minoxidil, and injectable GHK-Cu, despite minimal hair loss. Many users suggest reducing the dutasteride dose due to potential side effects and recommend starting with finasteride instead.

      community EMA is re-examining Winlevi (clascoterone at lower concentration)

      in Treatment  8 upvotes 9 months ago
      Clascoterone in Winlevi, a topical AR antagonist, is being re-examined due to concerns about HPA axis suppression in adolescents, but it's unlikely to be banned for adult use in androgenetic alopecia (AGA). The European Medicines Agency recommended refusing Winlevi for acne vulgaris, but this may not affect Breezula's approval for AGA.

      community Does low HGH leading to hairloss?

      in Research/Science  12 upvotes 2 years ago
      The user experiencing diffuse hair loss is using various treatments including RU58841, finasteride, minoxidil with tretinoin, anti-hair loss shampoo, and microneedling, and is considering adding peptides TB500, BPC157, and GHK-Cu. They have low growth hormone levels and are questioning its impact on hair loss, while another user suggests androgenic alopecia and androgens are likely the main cause of hair loss.

      community The mechanism of androgenic alopecia

      in Research/Science  34 upvotes 6 months ago
      DHT may inhibit hair growth by affecting mitochondrial function, leading to hair follicle miniaturization. Treatments like minoxidil and PP405 may promote hair growth by altering metabolic pathways, potentially counteracting DHT's effects.

      community 8.5 month transplant + meds update - 2,689 grafts

      in Transplants  378 upvotes 2 years ago
      Ibrox1972 shared an 8.5-month update on their 2,689-graft hair transplant by Dr. Raghu Reddy in London, along with using oral finasteride, oral minoxidil, and microneedling. Users praised the natural-looking results and discussed the importance of choosing a skilled doctor.
      Smp density or 2nd hair transplant?

      community Smp density or 2nd hair transplant?

      in Hair Transplants  103 upvotes 9 months ago
      The user is considering a second hair transplant or scalp micropigmentation to address thinning in the crown area and hide scars from a previous transplant. They have been using finasteride and minoxidil for three years but are concerned about the appearance of their donor area and the effectiveness of scalp micropigmentation.

      community My Experience and a Discourse on "DUPA"

      in Treatment  9 upvotes 1 year ago
      The user discusses their hair loss experience, exploring various hypotheses including thyroid levels, vitamin D, DHEA, nutritional deficiency, diabetes, seborrheic dermatitis, lack of nutrition to hair follicles, chronic inflammation, female pattern hair loss causes, cortisol, and prolactin levels. They are currently using finasteride, beta-sitosterol, and have tried topical dutasteride and microneedling therapy.

      community Got a 3,5K graft hair transplant at 22.

      in Transplants  120 upvotes 1 month ago
      A 22-year-old had a 3,500 graft hair transplant to restore his original hairline and improve density, while using dutasteride and oral minoxidil to manage hair loss. He believes being proactive with medication prevented further loss and allowed for a successful transplant.

      community 2 years of dut, great result i’ve seen, hairline is coming back

      in Is this regrowth?  137 upvotes 1 year ago
      The conversation is about a user sharing positive results from using dutasteride for hair regrowth over two years, with others discussing the effectiveness and experiences with hair loss treatments like finasteride and minoxidil. Some users request before-and-after photos to assess the effectiveness of the treatment.

      community Vitamin D deficiency hair loss

      in Chat  10 upvotes 2 years ago
      A 20-year-old male has been experiencing hair loss for three years due to a vitamin D deficiency and has seen no improvement after 3.5 months of taking supplements. Another person suggested that if the hair loss follows a pattern, it might be regular baldness rather than due to the deficiency.

      community What is the cause of "DHT itch"?

      in Research/Science  7 upvotes 11 months ago
      The conversation discusses the effects of using Tongkat ali and dioscorea to raise DHT levels, leading to increased body hair growth and an itchy scalp, without causing hair loss. The discussion also debates the role of DHT in male characteristics and its impact on sexual function, with differing opinions on its importance and effects.

      community Follicum releases some data from previous phase 2a trial

      in Research/Science  13 upvotes 2 years ago
      Follicum discovered that their drug FOL-005 increased hair count by 12 hairs per cm2 in patients with less than 255 hairs per cm2 and is planning a phase 2b trial. They are currently fundraising for the trial, and the drug may also be effective for women.

      community Pelage Recruiting Now for Phase 2

      in Research/Science  10 upvotes 1 year ago
      Pelage is recruiting for phase 2 trials, showing promise for treating bald regions. The discussion highlights its potential effectiveness based on its mechanism of action.

      community Results from 272 diode Red Light Therapy hat exclusively.

      in Is this regrowth?  248 upvotes 2 months ago
      A user reported noticeable hair regrowth using a 272 diode red light therapy hat over 11 months without Minoxidil or Finasteride. Opinions vary on its effectiveness compared to traditional treatments, with some suggesting combining therapies for better results.

      community Will we ever hear about HMI -115

      in Update  20 upvotes 2 years ago
      Hair loss discussion includes treatments Minoxidil, Finasteride, and RU58841. Update on HMI-115 clinical trial expected in July or August.