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      community It is what it is with some people

      in Satire  162 upvotes 4 months ago
      Hair loss treatments like finasteride and dutasteride are discussed, with concerns about side effects such as depression and brain fog. Some users argue about the necessity and impact of DHT on libido and other bodily functions.

      community 1 year progress 5% topical minoxidil daily and 1mg fin daily

      in Is this regrowth?  462 upvotes 5 months ago
      The user experienced positive hair regrowth using 5% topical minoxidil daily and 1mg finasteride daily but had to stop finasteride due to side effects like depression, anxiety, and gynecomastia. They are considering alternatives like topical finasteride or dutasteride and are currently using only topical minoxidil.

      community Minoxidil works amazingly, you just need to give it time.

      in Minoxidil  326 upvotes 5 months ago
      Minoxidil can effectively promote hair regrowth with consistent use, but results differ among individuals. Some recommend combining it with finasteride for better long-term results, though OP chooses to use only minoxidil and accepts the possibility of going bald.

      community My Theory Of Androgenic Alopecia

      in Research/Science  20 upvotes 5 months ago
      Hair loss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.

      community Someone please explain the Dut horror stories

      in Finasteride/Dutasteride  9 upvotes 6 months ago
      Dutasteride is often blamed for worsening hair loss, but initial shedding may lead to improvement, requiring patience. Some users find success with dutasteride, finasteride, and minoxidil, while others experience side effects or no improvement.

      community Don’t do like me. Don’t take a long break from Fin and Min

      in Chat  124 upvotes 6 months ago
      Stopping finasteride and minoxidil can cause significant hair shedding, so they should be continued indefinitely. Concerns about finasteride affecting fertility or causing birth defects are mostly unfounded, but some stop for personal reasons.

      community Why you may be taking Dutasteride wrong

      in Finasteride/Dutasteride  63 upvotes 6 months ago
      Dutasteride is more effective than finasteride for hair loss, with optimal dosing at 0.5mg once or twice a week to minimize side effects. Topical application may further reduce side effects while effectively lowering scalp DHT.

      community Can be this a new game changer? What's your Opinion about it

      in Treatment  521 upvotes 6 months ago
      The conversation discusses skepticism about new hair loss treatments, with many users expressing doubt about their effectiveness compared to existing treatments like minoxidil and finasteride. Some users mention natural oils like olive and macadamia oil, but overall, there's a consensus that these are unlikely to be game changers.

      community Is Finasteride the only way to reduce scalp DHT?

      in Chat  28 upvotes 6 months ago
      A 24-year-old male experienced side effects like low libido and ED after starting finasteride post-hair transplant and is seeking alternatives to reduce scalp DHT. Suggestions include topical finasteride, Xpecia, DHT-reducing shampoos, and switching to dutasteride, with some users reporting fewer side effects with these alternatives.

      community P-1075: a BETTER version of Minoxidil

      in Research/Science 6 months ago
      P-1075 is a more potent hair growth agent than Minoxidil, but it poses significant heart risks, making it unsafe for use. Despite promising results in macaques, concerns about its cardiotoxicity in rats have halted its development.

      community One year on finasteride has reversed some aging

      in Chat  198 upvotes 7 months ago
      Finasteride and minoxidil use resulted in a more youthful appearance and improved skin. There is debate about their effects on collagen and skin aging, with no solid evidence supporting significant changes due to finasteride.

      community 200 days on dut + min, what do you think?

      in Is this regrowth?  602 upvotes 7 months ago
      The user reports significant hair regrowth after 200 days using dutasteride and minoxidil, attributing changes to hair dye. Others doubt the authenticity and discuss treatment effectiveness and side effects.

      community The mechanism of androgenic alopecia

      in Research/Science  34 upvotes 7 months ago
      DHT may inhibit hair growth by affecting mitochondrial function, leading to hair follicle miniaturization. Treatments like minoxidil and PP405 may promote hair growth by altering metabolic pathways, potentially counteracting DHT's effects.

      community 5 months on dut/fin/min progress

      in Progress Pictures  175 upvotes 7 months ago
      The user experienced significant hair regrowth after 5 months using finasteride, dutasteride, and oral minoxidil, despite initial side effects like erectile dysfunction, which resolved after switching from finasteride to dutasteride. The user reports full recovery of hair density and improved skin condition, though the right temple remains slightly recessed.

      community One year off fin/min and I regret it

      in Update  413 upvotes 7 months ago
      The user regrets stopping finasteride and minoxidil due to side effects but plans to resume treatment. They consider using finasteride every other day and continuing topical minoxidil to manage side effects while maintaining hair.

      community Federal Grant Cuts have impacted PP405 related research

      in Technology  457 upvotes 8 months ago
      Federal funding cuts have delayed PP405 research, affecting hair loss treatment progress, though clinical trials will continue. The discussion highlights PP405's potential compared to minoxidil and finasteride and stresses the importance of government-funded research.

      community Yes your lifestyle and diet has its role in hair loss.

      in Chat  296 upvotes 8 months ago
      Diet and lifestyle changes can reduce hair shedding but won't regrow hair lost to genetic male pattern baldness. Treatments like finasteride and dutasteride are necessary for significant hair regrowth.

      community Do studies say Finasteride shed is real?

      in Finasteride/Dutasteride  12 upvotes 8 months ago
      Finasteride may cause hair shedding as part of the regrowth process, but there are no controlled trials confirming this. The shedding idea is mostly based on anecdotal reports and comparisons to how minoxidil works.

      community JXL082 is not PP405 and Everychem followed the wrong lead

      in Research/Science  41 upvotes 9 months ago
      JXL082 is not the same as PP405, leading to a halt in sales and a plan to synthesize the real PP405. There is skepticism about the safety and effectiveness of JXL082 and PP405, with concerns about patent issues and the long-term impact on hair growth.

      community Dutasteride power compared to finasteride

      in Finasteride/Dutasteride  15 upvotes 9 months ago
      Dutasteride is generally considered more effective than finasteride for hair regrowth, with some users experiencing better results, especially at higher doses. However, individual responses vary, and some users report side effects or no response to either treatment.

      community 6 months on dutast and minoxodil, hair growing like weeds now!

      in Progress Pictures  618 upvotes 10 months ago
      A woman experienced significant hair regrowth after six months of using dutasteride and minoxidil, despite initial hair loss due to androgenetic alopecia. She reported minimal side effects and highlighted the effectiveness of these treatments for women, despite doctors' hesitancy to prescribe them.

      community Why do we get bald from evolutionary perspective

      in Chat  213 upvotes 10 months ago
      Baldness is not an evolutionary disadvantage because it occurs after reproductive age. Treatments like Minoxidil and Finasteride are used for androgenetic alopecia but don't address the root cause.

      community Dutasteride Users, do you Still Take Creatine?

      in Finasteride/Dutasteride  11 upvotes 10 months ago
      The conversation discusses the potential impact of creatine on hair loss, with some users sharing personal experiences of increased shedding while others argue there's no scientific evidence linking creatine to hair loss. The original poster switched from finasteride to dutasteride and is considering resuming creatine after monitoring its effects on hair loss.