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      community HMI-115 update: Chime Biologics and Hope Medicine Enter Manufacturing Agreement to Speed up the Launch of First-in-class Antibody Drug HMI-115 Targeting Endometriosis and Androgenic Alopecia

      in Research/Science  109 upvotes 2 years ago
      Chime Biologics and Hope Medicine are speeding up the launch of a first-in-class antibody drug, HMI-115, for endometriosis and androgenic alopecia. The treatment involves a series of subcutaneous injections, has shown promising results in phase 1, and continues to promote hair regrowth even after the treatment is stopped.

      community What is your opinion on HMI-115?

      in Treatment  16 upvotes 3 years ago
      HMI-115, a potential treatment for hair loss that has been reported to produce significant regrowth in bald areas. It is the closest thing to a cure currently available and has raised hope that it could make hair transplants obsolete.

      community Hope Medicine HMI-115 got 28M$ investment

      in Research/Science  59 upvotes 2 years ago
      Hope Medicine received a $28M investment for HMI-115, a monoclonal antibody in phase II trials for treating androgenetic alopecia. Some users are skeptical about its effectiveness, while others find the investment and trial results encouraging.

      community (17M) Hair loss and Cystic Acnes / Dutasteride

      in Finasteride  109 upvotes 4 months ago
      A 17-year-old is using Finasteride and Minoxidil for hair loss, experiencing hair shedding and cystic acne. They are considering Dutasteride for acne but are concerned about potential side effects on genital development.

      community Shiseido RCH-01

       7 upvotes 7 years ago
      Shiseido RCH-01 and Replicel's upcoming trial data release. Users discuss expected release timelines and clarify quarter dates.

      community M[16] Thinning Hair Advice (Desperate)

       5 upvotes 11 years ago
      A 16-year-old is experiencing thinning hair at the front and shedding during showers. He is concerned about potential early baldness and is considering seeing a doctor and taking multivitamins.

      community The likely cost of HMI-115, when it comes out

      in Technology  11 upvotes 3 years ago
      A new potential hair loss treatment called HMI-115, and the cost of this treatment which may be expensive due to production costs but could be competitive with other treatments such as hair transplants.

      community My summation of PP405 - looks promising

      in Research/Science  208 upvotes 1 year ago
      PP405 shows promise for hair regrowth by manipulating stem cell characteristics and lactate dehydrogenase, with Phase 2a trials pending. Google Ventures' $15M investment suggests confidence, but results and market availability remain uncertain.

      community 17 months dut + min + 2800 grafts (5 months)

      in Progress Pictures  80 upvotes 9 months ago
      The user shared progress on hair restoration using dutasteride, oral minoxidil, and 2800 grafts, noting significant improvement in hair thickness and coverage. They discussed the importance of continuing DHT blockers like finasteride or dutasteride post-transplant to prevent further hair thinning.
      104 days of .5mg dut at 17 (read desc)

      community 104 days of .5mg dut at 17 (read desc)

      in Journals / Progress Pictures  81 upvotes 9 months ago
      The user has been using oral Dutasteride (.5mg) for 104 days and oral Minoxidil (.5mg) for about 2 months to address hair loss. Changes in hair appearance are noted, influenced by haircuts and dyeing, which affect the visibility of thinning areas.

      community What do we actually know about HMI-115?

      in Chat  16 upvotes 2 years ago
      The post and conversation are about HMI-115, a potential treatment for hair loss. The conclusion is that HMI-115 is not a 5ar-inhibitor and is instead a prolactin receptor inhibitor. Some users are skeptical about its effectiveness and believe that baldness will still be a problem in the future.

      community if hmi-115 truly works, we can just get off off fin?

      in Chat  19 upvotes 3 years ago
      A potential new hair loss treatment, HMI-115, and the possibility of discontinuing finasteride in favor of it. The conversation also includes discussion about other benefits of using finasteride.

      community 17 month finasteride update (title)

      in Progress Pictures  51 upvotes 1 year ago
      The user has been using finasteride since November 2023, which improved their hair and confidence, and they plan to switch to dutasteride and get a hair transplant. They noticed hair thickening after 3-4 months on finasteride and are considering oral dutasteride and minoxidil for further improvement.

      community TDM-105795 phase 2 results are in!

      in Research/Science  29 upvotes 2 years ago
      TDM-105795 showed promising hair growth results, with higher efficacy than placebo and minimal side effects. It activates dormant hair follicle stem cells and may maintain gains without immediate loss, unlike minoxidil.

      community Wuhan Hengheda Pharm WHP CB-03-01 Scam

       14 upvotes 6 years ago
      The conversation is about a user who experienced negative side effects and poor sleep after using an impure hair loss treatment 'CB' from Wuhan Hengheda Pharm, which did not offer a refund or proper customer service. The user had the product tested, confirming its impurity.

      community losing hair as a female 17-18 years old feels terrible

      in Female  15 upvotes 5 years ago
      A female, aged 17-18, is experiencing significant hair loss, feeling hopeless despite trying various treatments like leave-in conditioners, omega-3s, supplements, sulfate-free shampoo, and biotin. She is distressed as her hair continues to thin, affecting her body image and self-esteem.

      community Whats the deal with TDM-105795?

      in Research/Science  4 upvotes 1 month ago
      TDM-105795 is a potential hair growth stimulant that works differently from minoxidil and could be used alongside it for enhanced growth. It completed phase 2 trials in 2024, with a medium to high chance of release in 2026, but lacks recent updates or phase 3 trial information.

      community Nuking DHT at the age of 17 - My Hairloss StackπŸ’ͺ🏼

      in Treatment  6 upvotes 11 months ago
      A 17-year-old shares their hair loss treatment, using oral finasteride, dutasteride, stemoxydine, alfatradiol, and a placebo product, but cannot use minoxidil due to an allergic reaction. Others discuss similar treatments and question the use of dutasteride at a young age.

      community Finasteride to Dutasteride 6 months teenager 17M AMA

      in Progress Pictures  313 upvotes 1 year ago
      A 17-year-old is using oral dutasteride, finasteride, and topical minoxidil for hair loss, with plans to increase dutasteride and consider surgery. They report significant regrowth but are worried about side effects and the effects of blocking DHT at a young age.

      community M46 - 3 week progress on HIMS serum

      in Progress Pictures  12 upvotes 2 years ago
      A 46-year-old male shared his 3-week progress using HIMS serum with Finasteride 0.3% and Minoxidil 6%, showing improvement without noticeable shedding. His routine includes vitamins, a healthy diet, and specific hair care practices like microneedling and using caffeine solution.