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      community How You Can Help Speed Up the Verteporfin Trials

      in Research/Science  185 upvotes 2 years ago
      The post discusses speeding up verteporfin trials for hair loss treatment. The original poster, involved in the trials, requests help in crowdsourcing doctor emails to spread awareness and gather more support for the trials.

      community How many of you have significant others?

      in Shaved/buzzed  105 upvotes 2 years ago
      The conversation revolves around the experiences of different individuals with hair loss treatments like Minoxidil, Finasteride, and RU58841. The discussion includes various perspectives on the effects of these treatments, the importance of hair for self-esteem and attractiveness, and the influence of significant others on the decision to use or stop using these treatments.

      community PSA: If you're prone to MPB dont take creatine

      in Update  106 upvotes 2 years ago
      Creatine might speed up hair loss in those prone to male pattern baldness, possibly due to increased DHT levels. Some users experience no issues when using creatine with treatments like finasteride, minoxidil, or dutasteride.

      community POV: You Ask A Tressless User If It's Safe To Drink Minoxidil

      in Satire  769 upvotes 3 years ago
      This conversation is about how topical treatments for hair loss, such as Minoxidil and Finasteride, can be replaced by drinking oral versions of the same medications to achieve better results with less hassle. Some users have already been doing this with positive results.

      community Physician here AMA – 30M oral Fin 1-1.25 mg daily

      in Update  47 upvotes 3 years ago
      Hair loss treatments, specifically the use of finasteride, microneedling and potentially oral minoxidil. People discussed their experiences with finasteride, its effects on sexual behaviors, as well as potential solutions such as tadalafil or using other growth factor signal peptides for hope in curing male pattern baldness.

      community 2nd shed Update: Lost everything and still losing like crazy.

      in Update  176 upvotes 1 year ago
      The user experienced significant hair loss after initially successful treatment with minoxidil and finasteride, leading to a second shedding phase. They are considering switching to oral minoxidil for convenience and are advised to continue treatment despite the shedding, as regrowth is expected.

      community Why do barbers never mention if you’re balding?

      in Chat  317 upvotes 2 years ago
      People are discussing why barbers often don't mention their clients' hair loss, with some sharing personal experiences where barbers did suggest treatments like finasteride (Fin) or mentioned the possibility of hair transplants. Some barbers avoid the topic to not offend clients, while others openly discuss it and recommend treatments or acknowledge the issue when asked.

      community Being Safe on Oral Minoxidil: tl;dr on the literature.

      in Research/Science  49 upvotes 1 year ago
      Oral minoxidil is effective for hair loss but can cause cardiovascular side effects, such as pericardial effusion, especially in those with genetic predispositions. Starting with low doses and monitoring cardiovascular health are advised to reduce risks.

      community Anyone here get results from topical melatonin?

      in Research/Science  11 upvotes 4 years ago
      A user has been using finasteride and minoxidil for hair loss but is experiencing increased shedding and is considering using topical melatonin with a product called Rizn. Another user is skeptical about the effectiveness of topical melatonin due to issues with the research and lack of replication of results, while a third user expresses interest in the outcome of using Rizn after not seeing results from topical finasteride and minoxidil.

      community 3 months update on 3mg Dutasteride

      in Chat  98 upvotes 1 month ago
      The user saw no significant changes in hair loss after three months on 3mg Dutasteride, having previously used Finasteride and 0.5mg Dutasteride. They plan to continue the high dose for a year despite concerns about side effects and diminishing returns.

      community Regrowth with only Nizoral and Lifestyle Changes; focusing on scalp health & nervous system

      in Is this regrowth?  86 upvotes 2 months ago
      The user reported subtle hair regrowth by focusing on scalp health and lifestyle changes, using Nizoral shampoo and methods to reduce inflammation and cortisol, without using finasteride, minoxidil, or other common treatments. Opinions in the conversation varied, with some skeptical of the results and others acknowledging the potential benefits of addressing scalp health and inflammation.

      community Suffer so bad I want it to end

      in Chat  111 upvotes 1 year ago
      A 23-year-old is distressed about hair loss despite using dutasteride and oral minoxidil and is considering a hair transplant in Turkey. Many suggest therapy, hair systems, or acceptance, emphasizing mental health over appearance.

      community Verteporfin and Microneedling

      in Treatments 1 year ago
      Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.

      community Clascoterone 5% solution infographic

      in Update  130 upvotes 4 months ago
      Clascoterone 5% solution is discussed as a potential new treatment for hair loss, offering an alternative for those who can't use finasteride or need additional options beyond minoxidil. Concerns about cost, effectiveness, and safety compared to existing treatments like RU58841 and finasteride are highlighted.

      community You would never even know - Matthew McConaughey

      in Chat  1373 upvotes 4 months ago
      Matthew McConaughey likely maintains his hair using finasteride, minoxidil, hair transplants, and possibly a hair system. Products like Reginix or rosemary oil are not considered as effective as these treatments.

      community The amazing fast pace of PP405.

      in Chat  327 upvotes 6 months ago
      PP405 is a new hair loss treatment advancing quickly in trials, generating excitement and skepticism about its effectiveness and marketing claims. Some see it as a potential alternative to minoxidil and finasteride, but concerns about long-term effects and the need for DHT blockers persist.

      community The mechanism of androgenic alopecia

      in Research/Science  33 upvotes 6 months ago
      DHT may inhibit hair growth by affecting mitochondrial function, leading to hair follicle miniaturization. Treatments like minoxidil and PP405 may promote hair growth by altering metabolic pathways, potentially counteracting DHT's effects.

      community 7 months using Dutasteride Horror, before and after

      in Minoxidil  51 upvotes 6 months ago
      The user experienced significant hair loss after starting dutasteride, despite improved libido and gym performance. They previously used finasteride but stopped due to side effects and are considering combining treatments or a hair transplant.

      community 23M Couldn’t go bald for fear of my Girlfriend leaving me.

      in Is this regrowth?  1096 upvotes 8 months ago
      A 23-year-old man uses a topical spray with minoxidil, finasteride, and tretinoin for hair loss, experiencing improved hair growth but occasional heart palpitations. He worries his girlfriend might leave him if he goes bald, but commenters advise that if she would leave over hair loss, she isn't worth it.