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      community [Nov 2019] The peptide AC 2 isolated from Bacillus-treated Trapa japonica fruit extract rescues DHT (dihydrotestosterone)-treated human dermal papilla cells and mediates mTORC1 signaling for autophagy and apoptosis suppression

       22 upvotes 6 years ago
      A peptide from Japanese water chestnut fruit may help with hair loss by suppressing DHT's effect on hair follicle cell death, potentially serving as a finasteride alternative. The treatment's effectiveness and safety in humans remain uncertain.

      community DHT blocking ingredients

      in Treatment  6 upvotes 5 years ago
      The conversation discusses DHT blocking treatments for hair loss, specifically mentioning Minoxidil, Finasteride, and organic flaxseed oil containing omega-3 fatty acids. It highlights skepticism about alternative treatments and emphasizes the proven effectiveness of Finasteride and Dutasteride.

      community Ben Greenfield Podcast : CHK-Cu & C-60

      in Research/Science  5 upvotes 4 years ago
      CHK-Cu (copper peptide) and C-60 (branched carbon chain) are discussed as potentially more effective than minoxidil for hair regrowth. Some users are skeptical about the claim that DHT isn't the root cause of hair loss, and others are trying these products to see if they work.

      community How long are Pelage going to milk the phase 2a results of PP405?

      in Chat  21 upvotes 4 months ago
      PP405, a potential hair loss treatment, is facing delays in releasing Phase 2 results, causing frustration among users who compare it to past failed treatments. Despite skepticism, some remain hopeful about PP405's future, while others discuss alternative treatments like Clascoterone and its expected market release.

      community PP405 (Everychem 3HP) Users - Assemble and share your story!

      in Chat  19 upvotes 1 month ago
      Users discussed the effectiveness of Everychem's solution, similar to PP405, with some reporting improved hair thickness and new growth. Concerns were raised about safety and the legitimacy of the product, with some users advising against purchasing research chemicals.

      community treatment: oil your scalp, for dryness

      in Treatment 1 year ago
      A user asked if applying oil (olive, coconut, etc.) to the scalp for dryness and hair loss is effective, as recommended by a dermatologist. They expressed doubt about the advice and sought opinions on its usefulness.

      community Min + fin + dermastamp + botanical

      in Research/Science  2 upvotes 4 months ago
      The conversation discusses using minoxidil, finasteride, a dermastamp, and botanical oils like peppermint, rosemary, and pumpkin seed oil for hair growth. The user is considering using Alpha Infuse, which combines microneedling with plant oils, to enhance results.

      community Hair loss++ oil for hair growth

      in Product 10 months ago
      The conversation discusses hair loss treatments, specifically using rosemary oil and biotin hair oil. Users suggest that medication might be more effective than these oils.

      community What supplements or extra dtuff do you guys do for your hair?

      in Product  2 upvotes 1 year ago
      OP uses multivitamins, collagen, biotin, keratin, omega-3, satin bonnet, dandruff shampoo, oil moisturizer, and sun exposure for hair care. Users suggest adding antioxidants, probiotics, pumpkin seed oil, vitamin D, iron, and dermastamping.

      community Peppermint oil for Hair Thickness

      in Research/Science  2 upvotes 6 months ago
      Peppermint oil may increase hair thickness more effectively than minoxidil, but its effects are mostly studied in animals. Users report mixed results, with some seeing no regrowth and others noting slight improvements when combined with other treatments.

      community Can't find 2% keto in my region

      in Ketoconazole  21 upvotes 3 years ago
      User can't find 2% keto shampoo in their area and asks about ketoconazole BP20. Replies confirm that 20mg/ml means 2% ketoconazole and BP stands for British Pharmacopoeia, ensuring purity and quality standards.

      community Rosemary oil's potency as a dht blocker

      in Research/Science  65 upvotes 2 years ago
      Rosemary extract showed high inhibitory activity against DHT, similar to finasteride and dutasteride, but the conversation includes skepticism about its effectiveness in humans since the study was done on mice and rosemary oil is often considered ineffective based on personal experiences. Some suggest trying rosemary oil alongside other treatments, while others emphasize the difference between the extract used in the study and the oil.

      community Correct proportion of topical oils - castor, rosemary, peppermint

      in Treatment  8 upvotes 2 years ago
      The conversation is about finding the correct proportions of topical oils for hair loss treatment. The proposed mixture includes 10ml castor oil, 2ml rosemary essential oil, 1ml peppermint essential oil, and 1ml tea tree essential oil, applied three times weekly.

      community RU58841 in Pumpkin Seed Oil (PSO)

      in Treatment  4 upvotes 1 year ago
      A user is seeing good results with RU58841 for hair loss, noting reduced shedding and thicker hair. They plan to use pumpkin seed oil as a solvent to avoid water content, which they believe reduces the effectiveness of anti-androgens.

      community Does anyone here use coenzyme Q10 for hair loss?

      in Chat  2 upvotes 1 month ago
      The conversation is about using coenzyme Q10 for hair loss alongside dutasteride. The effectiveness of coenzyme Q10 for treating androgenetic alopecia is questioned due to a lack of evidence.

      community ghk-cu is potent 5-ar inhibitor?

      in Product  10 upvotes 2 years ago
      GHK-Cu is a potent inhibitor of the type 1 5-alpha reductase enzyme in hair follicles, which may reduce hair loss without the side effects associated with type 2 5-alpha reductase inhibitors. The user previously experienced side effects with 5-alpha reductase inhibitors and is considering GHK-Cu as an alternative.

      community Triple Hair TH-16 released. Thoughts and opinions?

      in Product  33 upvotes 4 years ago
      Triple Hair's TH-16, a product claimed to be more effective than Minoxidil 5%, has been released; it contains melatonin and resveratrol. One user reported success with topical melatonin and dermarolling.

      community for anyone using saw palmetto oil

      in Research/Science  19 upvotes 5 months ago
      The conversation discusses using saw palmetto oil to reduce hair loss, with the user reporting decreased shedding but no regrowth yet. The user plans to try minoxidil and finasteride, noting previous success with minoxidil but concerns about its greasiness.