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      community DIY Topical Fin/Min solution thoughts

      in Research/Science  3 upvotes 2 months ago
      A user is experimenting with a DIY topical solution combining finasteride and minoxidil for hair loss, applying 0.5 mg of finasteride daily. Concerns include absorption issues, potential side effects, and product loss due to hair density, with some users suggesting oral intake for better results.

      community Fluridil degrades the androgen receptor.

      in Research/Science  12 upvotes 10 months ago
      Fluridil degrades androgen receptors, which are prevalent in the scalp and other tissues. People with androgenetic alopecia (AGA) may have higher expression of these receptors and 5AR activity in affected scalp areas.

      community Pyrilutamide ,the molecule’s true nature

      in Research  302 upvotes 1 year ago
      Pyrilutamide is a selective AR antagonist with a high binding affinity, making it effective in competing with DHT for androgen receptors. The 1% concentration is more effective than the 0.5%, but the latter may suffice for mild hair loss; the drug is considered a good option for those avoiding 5AR blockers due to side effects.

      community How to mix Viagra for topical application?

      in Treatment  6 upvotes 3 years ago
      The conversation is about experimenting with topical Viagra or Cialis for hair loss, including methods for dissolving the tablets. The user is also using herbal oil massages and considering using Ethanol/Propylene Glycol for better dissolution.

      community Hair care products and shampoos

      in Product  2 upvotes 5 months ago
      People are discussing hair care products and shampoos, with some using ketoconazole 2% and others mentioning products like NATIVE brand and Dr. Bronner’s peppermint soap. There's a focus on scalp health and the potential benefits of certain shampoos for aiding minoxidil absorption.

      community Fin is killing my eyes. Alternatives?

      in Treatment  6 upvotes 2 years ago
      A user experienced severe dry eyes as a side effect of using topical and oral Finasteride for hair loss and is seeking alternative treatments. They are considering other anti-androgens like Dutasteride, RU58841, Pyrilytamide, and Fluridil, despite mixed results and potential side effects.

      community How dependent will my other hairs get on minoxidil?

      in Minoxidil  12 upvotes 1 year ago
      A user is starting a finasteride and minoxidil routine for diffuse pattern hair loss and is concerned about hair dependency on minoxidil. Responses suggest that new hairs may not survive without minoxidil, but existing hairs won't fall out if minoxidil is stopped, though experiences vary.

      community I’m Quitting ketoconazole shampoo

      in Ketoconazole  2 upvotes 1 year ago
      A user is quitting ketoconazole shampoo, believing it worsened their hair condition, and plans to use clarifying, keratin, and pH balanced moisturizing shampoos instead. Another user suggests using conditioner after ketoconazole to prevent dryness.

      community Nizoral ketaconazole any good for dht reduction

      in Ketoconazole  8 upvotes 4 years ago
      A 17-year-old is looking for alternatives to finasteride for DHT control to preserve hair, considering ketoconazole shampoo for its potential to inhibit 5AR and also thinking about using caffeine-containing shampoos like alpecin or watermans.

      community Can HMI-115 reverse miniaturization?

      in Research/Science  12 upvotes 3 years ago
      HMI-115, a potential treatment for hair loss that can reverse miniaturization and make individual hairs thicker, as evidenced by data from macaques given the treatment and one subject in the phase I trial.

      community Are these all vellus hairs that will go terminal?

      in Is this regrowth?  7 upvotes 6 months ago
      The user is using oral minoxidil, ghk-cu, and HGH for hair regrowth, noticing small vellus hairs on the crown. They avoid traditional DHT blockers like finasteride due to side effects, despite skepticism from others about the effectiveness of ghk-cu.

      community Low level chronic allergies and hair loss

      in Research/Science  5 upvotes 2 years ago
      Hair loss can be influenced by chronic low-level allergies, and treatments like fexofenadine or topical cetirizine may help with regrowth. The user avoids finasteride, dutasteride, and minoxidil, and has tried Regenera Activa and PRF sessions.

      community Best solution for pyrilutamide in UK?

      in Treatment 2 years ago
      The user is looking for a PG-free solvent in the UK or EU to make their own pyrilutamide solution for hair loss and is currently using finasteride, considering minoxidil. They hope pyrilutamide will help stabilize their hair loss.

      community Scalp health/dandruff

       6 upvotes 6 years ago
      User is experiencing a very dry scalp with thick white flakes from using liquid minoxidil twice daily for a year. They use Nizoral every 10 days and are seeking advice for a healthier scalp, with a suggestion to use finasteride instead.

      community Keratin fibers vs. Gossypium Herbaceum Hair fibers

      in Product  1 upvotes 1 year ago
      The conversation is about comparing keratin hair fibers to Gossypium Herbaceum hair fibers for diffuse hair loss. The user prefers keratin fibers for their durability and is seeking a bulk purchase option.

      community I wrote a poem about pp405 (potential treatment)

      in Satire  19 upvotes 1 year ago
      A poem humorously suggests hope for a new hair loss treatment, PP405, while users debate the effectiveness and side effects of current treatments like Finasteride. Concerns are raised about Finasteride's side effects, especially for young users, and skepticism about new treatments is expressed.

      community Fevipiprant 2019!

       15 upvotes 9 years ago
      The conversation discusses Fevipiprant, an asthma drug that may block CRTH2 and potentially stop male pattern baldness (MPB) without inhibiting DHT. It also mentions the use of finasteride and dutasteride for hair loss.

      community is Oleanic acid a DHT blocker ?

      in Treatment  4 upvotes 1 year ago
      A user is experiencing hair thinning and is using a peptide with oleanic acid as a DHT blocker, along with minoxidil, while waiting for topical finasteride. They plan to use a combination of minoxidil, finasteride, dermastamp, ketoconazole, and scalp massages, but are advised to stick to proven treatments like finasteride and minoxidil.
      Thinning hairline. Will treatments work?

      community Thinning hairline. Will treatments work?

      in General  118 upvotes 1 year ago
      The user is experiencing hair thinning and plans to use minoxidil and finasteride spray from Hims, while currently using minoxidil foam. They are advised to treat possible seborrheic dermatitis and consider scalp health for hair loss improvement.