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      community CB-03-01 / Breezula Personal Results

      in Treatment  17 upvotes 3 months ago
      The user shared their experience with CB-03-01 (Breezula/Clascoterone) for hair loss, noting reduced shedding and improved hair appearance but experiencing significant sleep disturbances and low energy due to HPA axis suppression. They decided to stop using it due to these side effects and are waiting for GT20029 as an alternative.

      community Additional supplements / peptides to maximize finasteride benefit

      in Research/Science  3 upvotes 2 weeks ago
      The user is using finasteride, HGH, GHK-CU, BPC-157, KPV, biotin/collagen/keratin vitamins, ketoconazole shampoo, and low-dose naltrexone to address hair loss, avoiding minoxidil due to past shedding experiences. Adenosine is discussed as a potential alternative to minoxidil, though it is noted to be expensive and hard to find.

      community Will pp405 have to be inserted rectally for full benefits?

      in Transgender  31 upvotes 6 months ago
      Pp405 is discussed as a potential hair loss treatment, with humorous suggestions about rectal administration for increased effectiveness. Users joke about unconventional methods and express willingness to try anything for hair regrowth.

      community New molecule PP405 vs exercise

      in Research/Science  38 upvotes 1 year ago
      PP405 targets hair follicle stem cells differently than exercise-induced lactate, suggesting exercise alone may not replicate its benefits. Minoxidil and finasteride are recommended alongside exercise for hair regrowth, with additional suggestions like spicy food and infrared exposure.

      community Extreme regimen and still miniaturized hairs. AGA is just impossible to beat.

      in Insane  35 upvotes 3 years ago
      A user's extreme regimen for hair loss, which includes taking oral and topical medications such as minoxidil, dutasteride, cyproterone acetate and bicalutamide, but still experiencing miniaturization. Suggestions were made to try other treatments such as RU58841 and Pyrilutamide, while also considering mental health treatment and advice on lookmaxxing.

      community Breezula 6 Month Topline Phase III Results Released

      in Research/Science  173 upvotes 6 months ago
      Breezula shows promising hair growth results, with up to 539% increase in hair count compared to placebo, and regulatory submissions are planned in the US and EU. Users are cautiously optimistic, noting the potential for Breezula to replace finasteride by targeting DHT without systemic effects.

      community If PP405 goes systemic this would be quite catastrophic

      in Research/Science  4 upvotes 1 year ago
      Concerns about the potential systemic effects and safety of PP405 for hair loss, with discussions on its comparison to existing treatments like finasteride and minoxidil. Users express skepticism about untested research chemicals and emphasize the importance of clinical trials to ensure safety and efficacy.

      community Rosemary Oil experiment 4 months in

      in Research/Science  46 upvotes 2 months ago
      A user experimented with applying pure rosemary oil to a single hair strand twice daily, observing increased thickness and pigmentation, but questioned if the oil or the application method caused the change. Some users noted rosemary oil might be as effective as 2% minoxidil for hair growth, though others warned about potential harm from using undiluted oil.

      community BREEZULA COVID UPDATE: Filing for Special Protocol Assessment with FDA

      in Research/Science  63 upvotes 6 years ago
      The conversation discusses the progress of Clascoterone (Breezula) for hair loss treatment, noting that COVID-19 delayed female trials by three months but Phase III trials for males are proceeding with a Special Protocol Assessment filed with the FDA. Users express hope for Breezula as an alternative to existing treatments like finasteride and minoxidil, despite concerns about its potential high cost.

      community only microneedling and supplements

      in Progress Pictures  67 upvotes 9 months ago
      The user used microneedling, zinc, vitamin D3, biotin, magnesium, saw palmetto, pumpkin seed oil, and a DHT-blocker shampoo with biotin for hair loss. They are considering adding minoxidil due to stagnation in progress.

      community Post Low-Level Laser Light Therapy Syndrome (PLLLTS )

      in Satire  6 upvotes 3 years ago
      Hair loss discussion includes LLLT treatments and a satirical condition called PLLLTS, causing patients to resemble lighthouses and attract moths. Some users express concern about others taking the satire seriously.

      community PTD-DBM Update: Q&A With Dr. Kang-Yell Choi

      in Treatment  13 upvotes 6 years ago
      PTD-DBM is being explored for hair regrowth by targeting CXXC5, with clinical trials expected after pre-clinical studies. Users express anticipation and skepticism about its effectiveness.

      community I’m taking Veradermics VDPHL01 - AMA

      in Treatment  174 upvotes 1 month ago
      A participant using Veradermics VDPHL01, an extended-release oral minoxidil, experienced significant hair regrowth from Norwood 6 to Norwood 3V without side effects. They plan to use dutasteride after the treatment to maintain results.

      community Does anyone else feel that the hype for PP405 has gone?

      in Chat  25 upvotes 1 month ago
      The conversation discusses skepticism and diminishing excitement around the hair loss treatment PP405 due to unclear trial results. It also mentions other treatments like finasteride, minoxidil, VDPHL01 (extended-release minoxidil), and GT20026 as potential options for hair loss management.

      community Stoped minoxidil 5 weeks ago and still bloated

      in Minoxidil  175 upvotes 1 year ago
      The user stopped using minoxidil 5 weeks ago due to facial swelling, which initially subsided but then returned. Despite a healthy lifestyle and normal test results, the user is concerned about the persistent bloating.

      community topical exosomes - experimenting

      in Treatment  1 upvotes 2 months ago
      The conversation is about experimenting with topical exosomes for hair loss treatment, alongside microneedling, Happy Head's gel-like topical, and Ordinary's hair serum. The user also mentions the availability of treatments like latanoprost and Redensyl.

      community PP405 - hair stem cell stimulation

      in Research/Science  53 upvotes 2 years ago
      PP405, a topical LDH inhibitor, has shown to stimulate hair follicle stem cell proliferation in humans with moderate hair loss. They are advancing to more detailed trials this year.

      community Did anyone tried exosome therapy

      in Treatment  1 upvotes 1 year ago
      Exosome therapy for hair loss is questioned for its effectiveness and authenticity. Users express skepticism, citing manipulated photos and high costs.

      community cant use minoxidil, is there anything else that can mimic the results?

      in Treatment  7 upvotes 1 year ago
      The conversation is about alternatives to minoxidil for hair growth, as the original poster experienced chest tightness from using it. They are currently using finasteride and considering options like rosemary oil, pumpkin seed oil, and other topical treatments, but acknowledge that minoxidil and finasteride are the most scientifically supported treatments.

      community Olympia hair growth formula; experience.

      in Product  2 upvotes 2 years ago
      A user shared their experience using the Olympia hair growth formula for a month and asked for others' opinions on its composition. The conversation focuses on the effectiveness of the formula, which includes Minoxidil, finasteride, and RU58841.

      community Trialing the probiotics BB536, PTA 6475 so you don’t have to

      in Research/Science  73 upvotes 11 months ago
      Probiotics like L. reuteri ATCC PTA 6475 and B. longum BB536 may improve hair growth and density by reducing inflammation and reversing DHT damage. The user is trialing these probiotics personally, ordering them from the U.S. to Canada, and plans to continue if no adverse effects occur.